Nathaniel Martin, Professor of Biological chemistry, wondered what would happen if you take an antibiotic that has been known for 70 years and try to improve it with the latest tools of modern chemistry. Turns out it can become up to a hundred times more potent and prevent the growth of some drug-resistant…

Bringing together chemists and physicists to thoroughly investigate how electrochemical processes work on the smallest scale. That is the goal of the new Advanced Nano-electrochemistry Institute of the Netherlands, or ANION for short. The consortium receives a Gravitation funding of 23.6 million euros…

The dark matter of biology: clumps of sugar molecules that, for example, form sugary webs around pathogens. We know very little about them. Wouter Remmerswaal threw all his talent into the challenge – both in the lab and as a modeller – and succeeded. He received his PhD on 12th September.

The Advanced Nano-electrochemistry Institute Of the Netherlands (ANION) consortium will receive 23.6m euros in Gravitation funding for research on important electrochemical processes for energy transition. An additional four consortia with members from Leiden have also been awarded funding.

How do molecules originate and evolve in space? And how does that ultimately determine the chemical composition of planets and their atmospheres? The Dutch Astrochemistry Network (DANIII) receives 1.6 million euros from NWO to find out. A large group of Leiden astronomers and chemists is contributing:…

Destroying proteins from the Golgi apparatus of the cell in a controlled manner. That is the focus of chemist Marta Artola’s pioneering research. By developing a groundbreaking technology to target specific proteins in the Golgi, Artola aims to unlock new ways for drug development. For this ambitious…

Not experiments and lab coats, but computers and artificial intelligence: this year's Nobel Prize in Chemistry went to the inventors of the groundbreaking AI model, AlphaFold. This programme accurately predicts protein structures based on their genetic code—a crucial step in understanding biological…

After hard work in the lab, Chemist Tirong Guo has developed a group of materials that provide a stable and efficient foundation for artificial photosynthesis. Will this enable the large-scale production of hydrogen and other useful compounds in the most sustainable way possible? Guo will defend her…

AMSTERDAM – On the evening of Tuesday, November 19, the Palace Symposium took place at the Royal Palace Amsterdam, with this year’s theme being ‘Biological Design Through Artificial Intelligence’. His Majesty the King and Her Majesty Queen Máxima hosted the event, and Princess Beatrix was also present…

Storing energy is one of the biggest challenges in the energy transition. Hydrogen could be a solution. Chemist Daan den Boer is researching how to make the chemical reaction needed to store energy in hydrogen as cheap and efficient as possible.

Sebastian Pomplun manages to reach proteins with drugs even where this was thought impossible. That is why he and his research group have been allowed to join Oncode Institute. With nine others, he had been selected from 72 applicants to contribute to Oncode Institute's mission: to accelerate breakthroughs…

On World DNA Day 25 April, Leiden University is pleased to focus the spotlight on Rosalind Franklin, whose name was given earlier this month to the Campus Square on the Leiden Bio Science Park. This square will now be known officially as the Rosalind Franklin Square.

Sebastian Pomplun receives an ERC starting grant of 1.85 million Euros in five years. He wants to develop synthetic transcription factors that can enter cells and activate or deactivate specific genes. For example to disrupt cancer-related processes or to trigger the production of an important missing…

Leiden University has recently received various petitions from students and staff concerning our ties with Israeli universities. We have also held extensive discussions with the University Council in response to questions raised on the subject. We think it important that our partners and research projects…

Video conferencing from your sitting room and algorithms on social media that know your interests: new technology is an increasingly integral part of our lives. At the same time there is a growing call to protect our privacy, and this is causing friction, at the University too. In part because of the…

Leiden patriot Pieter Vreede fought for greater popular influence. Historian Dirk Alkemade reveals how this pioneer used radical means to shape Dutch democracy.

Technology and privacy, trust and mistrust. A discussion about this broke out when the University installed scanners and students protested. On Wednesday 2 February experts from Leiden University will explore this topic at the eponymous symposium. We called Roy de Kleijn, as a computer scientist and…

Researchers from Leiden University have developed a method to predict which sellers will be successful in illegal online marketplaces. This could help the police track down big players on the dark web, the hidden part of the internet.

A CT scanner to treat eye cancer, energy-efficient software for the future and a test to identify male chick eggs. Three projects by researchers from Leiden University are to receive funding from research funder NWO’s Open Technology programme, to which the business sector also contributes.

The universities of Delft, Leiden and Rotterdam are working together to show their students what artificial intelligence (AI) means for their own field. Three AI minors will start in the 2022 – 2023 academic year and will answer questions such as: ‘How best can you use AI in your research discipline?’…

For conducting experiments involving animals, you need a project license and a valid research plan. On this page, you will read what this entails and how to submit these documents. You will also find other relevant information regarding conducting research involving animals here.

Research, Transferable skills

What happens in the brains of people with psychiatric illnesses? With a €23.23 million gravity grant, scientists from different fields will search for biological causes over the next decade. ‘By joining forces, we hope to improve diagnosis and treatment for patients with these diseases.’

PhD candidate Sibel Bahtiri is one of the new Faces of Science. In videos and blogs, she will show what life is like as a young researcher.

Security

In het Leids Universitair Medisch Centrum wordt gewerkt aan de ontwikkeling van een nieuw malariavaccin dat effectiever is dan de huidige vaccins.

Since its discovery thirty years ago, it remained a mystery: how does the body’s own marijuana move between nerve cells in the brain? Mario van der Stelt and his research group have now uncovered the answer. This insight could aid the development of new treatments for pain and neurological disorders…

Collaborating and learning from other fields – that is what bioinformatician Hannah Augustijn enjoys most about doing research. During her PhD at Leiden University, she developed new ways to search within bacteria for the antibiotics of the future.

James Webb life’s building blocks

Michiel Veldhuis received the most public votes for the C.J. Kok Public Award and may therefore call himself Discoverer of the Year. Veldhuis researches how climate change affects savannah ecosystems in Africa and how we can protect them.

How do you engage students? Sander van Kasteren knows how to do that like no other. ‘He compares immune cells to Pokémon and doesn’t just give information; he tells stories,’ students say about their favourite lecturer, Sander van Kasteren. The Professor of Molecular Immunology passionately teaches…

Roll-up solar panels, bendable phone displays, or better computer chips… The EU project STIBNITE investigated the next generation of semiconductors, made from organic materials based on carbon, nitrogen, and boron. The project has now concluded. During the Open Science Debate on 1 July, the group will…

Biological chemist Nathaniel Martin and his team received an NWO grant to examine how blocking a specific enzyme in our body, NNMT, could be helpful in the treatment of some cancers. Trials with mice have been promising, and together with the Netherlands Cancer Institute, Martin wants to take the next…

Cookware handles, electrical plugs, brake pads. Unlike other plastics, these ‘thermosets’ cannot simply be melted down and reshaped, making them difficult to recycle. Chemist Roxanne Kieltyka and her team are now exploring a way to make these materials recyclable, potentially transforming the way we…

Scientific Director of the Leiden Academic Centre for Drug Research (LACDR) Hubertus Irth: ‘We test substances and look for new concepts for treating disease.’

Using the James Webb Space Telescope, an international team of researchers, including Leiden Professor of Molecular Astrophysics Ewine van Dishoeck, has discovered a palette of hydrocarbons in a planet-forming disc around a young, low-mass star. The results confirm that discs around very lightweight…

Bringing your drug candidates to patients is what many academic chemists dream about, but the road to this goal is long and bumpy. Now, Leiden small molecule nizubaglustat is ready for phase 3 clinical trials. This is thanks to a €132 million funding secured by the biotech spin-out Azafaros.

The European Research Council (ERC) has awarded an Advanced Grant to six Leiden researchers. It awards these significant grants to established principal investigators for ground-breaking, high-risk research.

Leiden University has had a turbulent week. There have been protests inside and outside our buildings that have evoked reactions, and students and staff have felt unsafe. We want with this message to look back at the past week and look forward to the future. What happened and how do we now want to move…