Gayathri Jaikamur has been awarded by the Dopper Foundation in the Change Make Challenge. She is a student of Masters Biology (Specialisation: Evolution, Conservation and Biodiversity) from India - working under the supervision of CML-researcher Dr. Thijs Bosker (and co-supervision of Dr. Nadja Brun).…

Understanding the proces of electrochemical reactions is essential to improve the technology for the energy transition. Fuel cell cars, for example use hydrogen produced from the electrolysis of water. Mariana Monteiro did fundamental research on the process and won two prizes with her thesis.

The renovation of the Herta Mohr building (formerly known as Cluster Zuid) is completed. It is the third project in the redevelopment of the Humanities Campus. With the renewal of these buildings, the university ensures a sustainable campus with modern facilities. The university wants to create an attractive…

We would like to present to you a simple guidebook about living a sustainable life as a student in the cities of Leiden and The Hague. Whether you are a first-year student still trying to find your way around or already doing your masters – students wanting to explore more sustainable options and save…

Lecture

PhD defence

PhD defence

PhD defence

It takes years to develop new medicines, from the test tube to trials in humans. During the process it often happens that a drug that seems promising in the initial stage has to be dropped in a later phase. This costs time and money. Leiden University and the LUMC are working closely together to make…

Activity-based protein profiling (ABPP, also termed chemical proteomics), is one of the pillars of chemical biology, and at LED3 we have taken it to the next level. ABPP allows the assessment of protein function in live cells and tissues, which means that the activity of a complete protein family can…

Chronic pain, nausea or vomiting due to chemotherapy. If you suffer from such ailments, medicinal cannabis can be a godsend. Though a downside is that it can make patients high. Therefore, Leiden researchers from the Oncode Institute are investigating alternatives that do not make you high. In Nature…

With cancer, a person’s body cells grow uncontrollably. Putting together a detailed picture of how this comes about makes it possible to develop efficient therapies. Researchers at the Leiden University Medical Centre (LUMC) and Leiden University are working together to gain a better understanding…

Alexander Kros studies supramolecular systems in a biological environment. The unifying theme between the projects in my lab is specific molecular recognition, i.e. the intermolecular interaction between complementary molecules with high affinity and selectivity. Studying, imitating and dissecting processes…

If you are interested in Life Science and you are looking for a programme with ample opportunities to put together your own study path, our Life Science and Technology programme is the right choice. The programme focuses on societal problems at the molecular and cellular level.

Plant Sciences' contribution to the Development & Disease research theme is to unravel the processes that allow plants to adapt to changing abiotic and biotic environmental conditions or stresses, with the aim to contribute to the sustainable production of food, flowers and bio-based products using…

Learning from nature and utilizing microbial biodiversity to identify and characterize enzymes for degradation and upcycling of plastics and other polymeric materials.

Roll your sustainable sleeves! Our students and staff have found various ways to do just that, both at home and at our university.

This minor critically examines the complexities of food sustainability through ecological, socio-economic, political, and cultural systems.

Urban, Food, Water, Biodiversity, Resources and Energy: these are the main research topics of the Institute of Environmental Sciences. We always strive to be a global leader in our field. And make a real impact with both our research programmes.

Ever since the FDA approved the drug bedaquiline, which interferes with the bioenergetics of Mycobacterium tuberculosis by inhibiting the activity the F0F1-ATP synthase, respiratory-chain enzymes have been an active target space for the discovery of new antibiotics. To aid in this pursuit, we aim to…

Supervisor: Indira Nederpelt

Promotor: G.A. van der Marel, Co-promotor: J.D.C. Codée

Large parts of the research described in this Thesis aims at the development of oligopeptide-masked toxins and their in situ immunoproteasome-mediated activation.

The glycosylation reaction is a pivotal reaction in creating new and complex oligosaccharides.

Lysosomal storage disorders (LSDs) are a group of orphan diseases characterized by lysosomal dysfunction or impaired lysosomal catabolism and affect collectively about 1 in 5000 live births.

Promotor: E. Bouwman, Co-promotor: S. Bonnet

Bacteria often experience external challenges, such as changes in environmental conditions or attacks by bacteriophages.

Pancreatic ductal adenocarcinoma (PDAC) is the deadliest common cancer, with only 8% of patients surviving for five years. One reason for this poor outcome is that current chemotherapy treatments are highly toxic, often leaving patients too sick to receive treatment or forcing doctors to lower the dose…

Promotor: H.J.M. de Groot, Co-Promotor: A. Alia

Glycoconjugate vaccines are composed of microbial poly- or oligosaccharides covalently linked to a carrier protein.

Promotor: Prof.dr. G.J. Kroes

Promotor: Prof.dr. J.W.M. Frenken

Nanodiscs are small, disc-shaped structures designed to mimic biological cell membranes, composed of a lipid bilayer stabilized by scaffold proteins. Membrane proteins play crucial roles in essential processes such as nutrient and waste transport, molecular recognition, and cell signalling, making them…

With the powerful electron microscopes at NeCEN we study abnormalities in cells of blood vessels in cardiovascular disease, the interaction between pathogens and hosts in infectious diseases, molecular processes that cause cancer and the interaction between drugs and target proteins. Drug development…

If idioms employed in codes of conduct could be as idiosyncratic as examples suggest, then to what extent did early modern language of vice, too, persist in this genre?

Promotor: M.A.G.J. Orrit

Promotor: H.S. Overkleeft, Co-promotor: B.I. Florea

From surface science towards industrial practice using high-pressure scanning tunneling microscopy.

Bachelor and Master students of all chemistry related studies are more than welcome to take part in our research activities. We have projects on design and synthesis of biologically relevant compounds within an ongoing research project. Supervision, following the apprentice/teacher model, is one of…

Quantum Delta NL, a research programme in which Leiden University participates, has been awarded 615 million euros from the National Growth Fund to help develop the Netherlands into a top player in quantum technology.

Research training projects in the MCBIM group - Bachelor and master students of all chemistry related studies are more than welcome to take part in our research activities. We have various research projects, all in one way or another involving transition metal ions. Daily supervision in the laboratory…

In this research group, headed by Prof. Erik Danen, the aim is to unravel cellular signaling mechanisms in normal and diseased cells, with a long-standing interest in cell adhesion signaling. In complex multicellular organisms such as ourselves, a division of labor emerges where different tissues and…

Source: J Cheminform, Volume 7, Issue 1 (2015)

Engineered nanomaterials (ENMs) are widely used, and nanotechnological innovations grow with rapid pace. Studies on nanotoxicology have demonstrated that chemical toxicology as well as particle toxicology should be accounted for in predicting the safety of ENMs.

Promotores: Prof.dr. J. Zaanen & Prof.dr. K.E. Schalm

The changing status of anatomical collections from the early modern period to date.

Microbial rhodopsins are photosensitive pigments implemented in the growth and adaptation of a large population of microorganisms.

Grants awarded to molecular physiology research