Bringing your drug candidates to patients is what many academic chemists dream about, but the road to this goal is long and bumpy. Now, Leiden small molecule nizubaglustat is ready for phase 3 clinical trials. This is thanks to a €132 million funding secured by the biotech spin-out Azafaros.

Michiel Veldhuis received the most public votes for the C.J. Kok Public Award and may therefore call himself Discoverer of the Year. Veldhuis researches how climate change affects savannah ecosystems in Africa and how we can protect them.

James Webb life’s building blocks

Using the James Webb Space Telescope, an international team of researchers, including Leiden Professor of Molecular Astrophysics Ewine van Dishoeck, has discovered a palette of hydrocarbons in a planet-forming disc around a young, low-mass star. The results confirm that discs around very lightweight…

How do you engage students? Sander van Kasteren knows how to do that like no other. ‘He compares immune cells to Pokémon and doesn’t just give information; he tells stories,’ students say about their favourite lecturer, Sander van Kasteren. The Professor of Molecular Immunology passionately teaches…

Biological chemist Nathaniel Martin and his team received an NWO grant to examine how blocking a specific enzyme in our body, NNMT, could be helpful in the treatment of some cancers. Trials with mice have been promising, and together with the Netherlands Cancer Institute, Martin wants to take the next…

Cookware handles, electrical plugs, brake pads. Unlike other plastics, these ‘thermosets’ cannot simply be melted down and reshaped, making them difficult to recycle. Chemist Roxanne Kieltyka and her team are now exploring a way to make these materials recyclable, potentially transforming the way we…

In het Leids Universitair Medisch Centrum wordt gewerkt aan de ontwikkeling van een nieuw malariavaccin dat effectiever is dan de huidige vaccins.

Since its discovery thirty years ago, it remained a mystery: how does the body’s own marijuana move between nerve cells in the brain? Mario van der Stelt and his research group have now uncovered the answer. This insight could aid the development of new treatments for pain and neurological disorders…

Roll-up solar panels, bendable phone displays, or better computer chips… The EU project STIBNITE investigated the next generation of semiconductors, made from organic materials based on carbon, nitrogen, and boron. The project has now concluded. During the Open Science Debate on 1 July, the group will…

In order to stop a whole range of diseases or disorders at their source, you would have to be able to switch certain genes on or off. Sebastian Pomplun wants to develop substances that can do this very precisely. For example, he wants to disrupt cancer processes and make cells produce an important missing…

Collaborating and learning from other fields – that is what bioinformatician Hannah Augustijn enjoys most about doing research. During her PhD at Leiden University, she developed new ways to search within bacteria for the antibiotics of the future.

Scientific Director of the Leiden Academic Centre for Drug Research (LACDR) Hubertus Irth: ‘We test substances and look for new concepts for treating disease.’

The European Research Council (ERC) has awarded an Advanced Grant to six Leiden researchers. It awards these significant grants to established principal investigators for ground-breaking, high-risk research.

Aukje Beers combined theory and practice, as well as chemistry, biology, and computer models. In this way, she discovered two protein inhibitors during her master’s project that could contribute to the development of a new cancer drug. For her research, Beers received the Unilever Research Prize on…

Leiden University has had a turbulent week. There have been protests inside and outside our buildings that have evoked reactions, and students and staff have felt unsafe. We want with this message to look back at the past week and look forward to the future. What happened and how do we now want to move…

Leiden University has set up two committees to consider issues that are the focus of much attention within our community and society at large. They are the Knowledge Security Committee and the Fossil Fuel Industry Collaboration Committee. Former dean Joanne van der Leun will chair both.

The interdisciplinary AI & Society minor of Leiden University brings together students and lecturers from a wide range of disciplines. Together they look at the impact of AI on society. Students are enthusiastic about this merging of worlds.

Jildau Bouwman has been named as professor by special appointment of the chair ‘Remote Health Monitoring’ at Leiden University. The systems biologist and TNO Digital Health Innovation figurehead will investigate how digital solutions can contribute to better healthcare at home. ‘Home care is often more…

Nine students dove into a challenging iGEM project this summer. With their idea, they aim to make antibodies more efficient - and in the meantime learn at least as much about collaboration, creativity and their own future.

How safe are the nanoparticles in transparent sunscreen, anti-odour socks and bacteria-resistant plasters? Although microbes are present on all organisms, the tools that estimate the safety of nanomaterials still hardly take them into account. Bregje Brinkmann explored the role of these microbes during…

He had been emeritus for 13 years when he suddenly received an email from Poland. Professor of Inorganic Chemistry Jan Reedijk was awarded an honorary doctorate from Nicolaus Copernicus University in Toruń. During the celebration of the 550th anniversary of the birth of patron Nicolaus Copernicus,…

White clouds of ice-cold gas flowing across the floor. Magical, but be careful not to freeze your fingers off. We are of course talking about liquid nitrogen and helium. You may have seen the spectacular Freezing Physics science show by the student organisation Rino. But did you know that this commodity…

'It gave our team a big boost to hear that our work was valuable,' says medical chemist Elmer Maurits about the moment they won the Venture Challenge. With their company Iprotics, they want to develop a drug that can better treat patients with autoimmune diseases and blood cancers. 25,000 euros of prize…

Sometimes an idea seems so logical and elegant at first glance, that you later wonder why no one thought of it before. Two researchers from LACDR have teamed up to develop a completely synthetic alternative to antibodies—one that mimics their size, shape and function, but which is cheaper, more stable,…

When you think of a library, you probably picture books – or students quietly studying. But for subject librarian Rutger de Jong, most of the work happens online. ‘We never throw anything away. Everything produced here in the name of science should remain findable.’

Cramming from a book, making notes or learning summaries. In the past these were about the only ways to memorise your course material. But that has long since changed. Multimedia is the code word. But is it effective?

An international team of astronomers including Leiden professor Ewine van Dishoeck has observed the benzene molecule (C6H6) in a planet-forming disk around a young star for the first time. The observations tell us more about the forming of planets in this disc, like our own Earth. The scientists publish…

Young researchers met this month for the fifth Science Communication Summer School. ‘This is the first time some participants get to meet other researchers who also enjoy science communication. It’s great to see’, says Julia Cramer, one of the coordinators.

Jasper Knoester is the dean of the Faculty of Science. How is he doing, what exactly does he do and what does his day look like? In each newsletter, Jasper gives an insight into his life.

A flu virus could cause a pandemic. And then we would be poorly armed because flu viruses are starting to become resistant to flu medications like Tamiflu. Chemist Merijn Vriends successfully worked on an improved version of such medications. He will be awarded his doctorate on September 12th.

What do you do when you get the chance to meet Nobel Prize winners in your field? You say ‘yes’, of course! Two young chemists from Leiden had the opportunity to attend the Nobel Laureate Meeting in Lindau, Germany. They share what the experience was like.

Students and researches from all faculties at Leiden University are warmly invited to a lunch meeting on Monday 14 October, discussing the rise of AI and the challenges this poses for various governance structures. The event is hosted by Leiden University’s interdisciplinary programmes GTGC and SAIL…

From 1 March 2025, a new university ‘fossil fuel collaboration’ committee will assess potential new collaborations with the fossil fuel industry and determine whether they comply with the Paris Agreement.

How can the Netherlands help secure a peaceful future for Israel and Palestine? At a recent meeting at the university, two remarkable speakers shared their perspectives: Somaya Bashir, a Palestinian woman living in Israel, and Palestinian journalist, Houssam Khadra, who fled Gaza over a decade ago.

How can you ensure that more experimental drugs reach the finish line? At the moment, only one in twenty cancer drugs that are tested on humans makes it to the market. This is an enormous loss for patients and society. With a grant from the National Growth Fund, Oncode-PACT aims to efficiently select…