279 search results for “bioactieve molecular” in the Staff website
-
Flu stops when you block the enzyme that cleaves off virus particles
A flu virus could cause a pandemic. And then we would be poorly armed because flu viruses are starting to become resistant to flu medications like Tamiflu. Chemist Merijn Vriends successfully worked on an improved version of such medications. He will be awarded his doctorate on September 12th.
-
A smarter way to search for antibiotics
Bacteria carry countless hidden treasures in their DNA: fragments that could hold the key to new medicines. But how do you pick out the most promising ones from millions of options? ‘Look at the switches that turn genes on and off,’ says molecular biologist Gilles van Wezel.
-
Awaken sleeping antibiotics with ERC Advanced grant
To facilitate the search for new antibiotics. That is the aim of Gilles van Wezel, professor molecular biotechnology at the Institute of Biology Leiden (IBL). He wants to do this by looking at similarities in the DNA of antibiotic-producing bacteria. Van Wezel has been awarded an ERC Advanced grant…
-
‘Look beyond your own discipline’
Good research means looking beyond disciplinary boundaries, said Professor of Molecular and Cellular Biochemistry Remus Dame in his inaugural lecture on 10 May. Processes that take place on DNA shouldn’t only be researched in a test tube but also in living cells, for instance.
-
Foraging skills may have made the essential difference in the evolution of our huge brain
Hunter-gatherers acquire their food through complex gender-specific foraging techniques for a relatively stable and diverse supply of energy. New research indicates that this specialisation by boys and girls starts at a very young age. Most likely, this enabled the human species to evolve much larger…
-
Versatile antiviral proteins discovered with supercomputer
A single tiny molecule that can destroy flu, corona, HIV and Zika viruses? Yes, it really does exist. Biophysicist Niek van Hilten, who will receive his doctorate on 14 September, contributed to this discovery.
-
Examining DNA molecules one by one: how combining techniques can help us understand diseases such as dementia
‘By cleverly combining new techniques for analysing DNA at the level of individual molecules, we can achieve real breakthroughs in research into conditions such as dementia,’ predicts Professor John van Noort. Together with four leading biophysics research groups, he has written a review article in…
-
First detailed picture of ice in planet-forming disk
An international team of astronomers led by Ardjan Sturm of the Observatory has made the first two-dimensional inventory of ice in a planet-forming disk of dust and gas surrounding a young star. The researches, including Melissa McClure, used the James Webb Space Telescope and publish their findings…
-
Sebastian Pomplun joins Oncode Institute to accelerate breakthroughs in cancer research
Sebastian Pomplun manages to reach proteins with drugs even where this was thought impossible. That is why he and his research group have been allowed to join Oncode Institute. With nine others, he had been selected from 72 applicants to contribute to Oncode Institute's mission: to accelerate breakthroughs…
-
Oncode Accelerator funds preclinical development of cancer therapies
Through its Demonstrator Projects, the Dutch Oncode Accelerator consortium provides grants for preclinical cancer therapy development. The first call for these projects is open until September 2025.
-
From Leiden to Harvard: four questions for Julia Santos
Eight early-career researchers from around the world have been awarded a 51 Pegasi b Fellowship – a prestigious opportunity for astronomers. Julia Santos, a PhD candidate at Leiden Observatory, is one of them. We asked her four questions about this remarkable fellowship.
-
Countering nerve pain caused by chemotherapy with new drug
Nerve pain is one of the most common side effects of chemotherapy. It is therefore one of the biggest reasons for cancer patients to stop treatment early. Darcy Reynolds worked on new drug candidates against this pain during her bachelor's thesis. She developed a new series of molecules that increase…
-
National Growth Fund invests many millions in faster and more sustainable (cancer) drug development
On 14 April, the National Growth Fund awarded million euros in grants to two consortia in which Leiden's science faculty is involved. Pharma-NL will receive 80 million euros and Oncode-PACT 325 million euros. Pharma-NL wants to make medicines available to the patient faster and more sustainably. Oncode-PACT…
-
LACDR PhD-Postdoc event - 12 October 2022
On October 12th, the LACDR PhD-Postdoc event will be organized in castle Oud Poelgeest.
-
Two new programme directors to start in the new year
In early 2026, two new programme directors will begin their roles at FWN. Joost Broekens will take charge of the bachelor’s programme in Data Science and Artificial Intelligence (DSAI), while Sander van Kasteren will become programme director of the MSc in Life Science and Technology (LST).
-
Joke Bouwstra is the first woman to receive the Dr Saal van Zwanenberg Honorary Prize: 'Wonderful to be in a line of distinguished scientists'
Emeritus professor Joke Bouwstra (LACDR) will receive this year's Dr Saal van Zwanenberg Ereprijs: a tribute to her years of fundamental research on the skin and the transport of drugs through the skin. This is the first time the prize has gone to a woman.
-
Renske Donkers wins Young Star Award, students surprise lecturers
Molecular Science & Technology student Renske Donkers has won the second edition of the Young Star Award. During the ceremony on Wednesday 17 February, no less than three teachers were awarded the title 'Teacher of the Year'. Finally, students had a surprise in store for all teachers: with a video they…
-
Funding for Leiden projects that advance open science
Two Leiden projects have been awarded Open Science NL funding to make science more accessible to academia and the world outside. The projects will strengthen the open science infrastructure.
-
The hunt for nanoplastics is on
How do you count the nanoplastics in your body? Leiden researchers published a method in Nature Protocols today that should make this easier. Important for both environmental and medicine research.
-
Wood formation further explored by NWO-XL grant
Leiden researchers, Professor Remko Offringa and co-applicants Salma Balazadeh and Frederic Lens received an NWO-XL grant (2.5 million euros). Together with researchers in Wageningen and Groningen, they will study the genetic and environmental drivers of woodiness. From plant to molecule, the groups…
-
How Oncode-PACT is bringing new cancer medicines closer with 325 million in Growth Fund money
How can you ensure that more experimental drugs reach the finish line? At the moment, only one in twenty cancer drugs that are tested on humans makes it to the market. This is an enormous loss for patients and society. With a grant from the National Growth Fund, Oncode-PACT aims to efficiently select…
-
Why biology students and teachers value the E-learning skills platform
Students of the Biology minor course Molecular Design have successfully boosted their skills in collaboration, research and writing with the recently developed E-learning Skills Platform. The biology students and their teachers greatly value the initiative. ‘Sometimes I couldn’t believe what progress…
-
Werken aan een effectiever malariavaccin
In het Leids Universitair Medisch Centrum wordt gewerkt aan de ontwikkeling van een nieuw malariavaccin dat effectiever is dan de huidige vaccins.
-
Sabine van der Asdonk wins Gratama Science Prize 2021
For her research into complex family problems, an assistant professor in Forensic Family and Youth Care Studies Sabine van der Asdonk has won the Gratama Science Prize 2021, a prize for talented young researchers from the universities of Leiden and Groningen. The jury praised Van der Asdonk’s excellent…
-
New research at the Hortus: the delimitation of the genus Uvaria L.
In the tropical rainforests of Southeast Asia the soursop family (Annonaceae) can be found. The genus Uvaria is a part of this family, but it has not yet been described entirely correctly. That is what Annas Rabbani will be studying during the next four years as a PhD student at the Hortus botanicus…
-
Plastics are causing stress to crops (and biodegradable alternatives do too)
Micro- and nanoplastics cause stress to crops such as lettuce and carrots, PhD candidate Laura Julia Zantis found. This can lead to reduced growth and a lower nutritional value. Biodegradable plastics have this effect too, likely because of chemicals they release during degradation.
-
How drugs work better when encapsulated in nanoparticles
Chemist Tobias Bauer discovered ways to improve drugs by encapsulating them. Packages with iron nanoparticles, for example, can stimulate immune cells. Bauer will receive his PhD on 9 June.
-
AI model accurately predicts endometrial cancer recurrence
Researchers from the Leiden University Medical Center (LUMC) have developed an AI model that accurately predicts the risk of endometrial cancer recurrence.
-
Running Leiden Marathon in a 450th-anniversary t-shirt
Nearly 19,000 runners lined up at the start of Leiden Marathon on Sunday, among them students and staff from the university. For some this was their first race, for others a highlight of their year. This year, in celebration of our 450th anniversary, they ran in a special jubilee t-shirt.
-
Recent PhD defenses
Here we highlight the achievements of our latest PhD graduates, each of whom has made significant contributions to the advancement of the field of (bio)pharmaceutical sciences.
-
‘Using real-world data to enhance our healthcare system’
On 16 May 2022, Professor Michel Wouters from the Department of Biomedical Data Sciences at the Leiden University Medical Centre (LUMC), will deliver his inaugural lecture titled ‘Quality of Cancer Care: why the real world matters’. Wouters will use the opportunity to describe how quality registries…
-
LIBC Publieksdag 2025: hoopvolle inzichten in hersenonderzoek
From historical understandings to new treatments: during the Public Day of the Leiden Institute for Brain & Cognition, curious visitors learned how rapidly research into brain disorders is evolving. ‘I found the neurosurgery and the research on organoids on chips particularly fascinating.’
-
Modified caffeine molecules help medical research move forward
Before researchers can develop targeted drugs, they need to know exactly how a disease works. Biochemist Bert Beerkens created molecules that allow them to find out. He used caffeine as the basis for new molecules that enable research into certain receptor proteins on cells.
-
Post-lockdown ceremonies: corona-proof but festive nonetheless
After the lockdown, it was again possible to receive graduates and guests at the University. In recent weeks, BSc and MSc graduates from various study programmes were festively awarded their diplomas in a special corona-proof setting in the restaurant of the Gorlaeus Lecture Halls building. This resulted…
-
How a bachelor’s student contributed to better chemical simulations
Doğukan Yilmaz chose a study that aligned with his favourite subjects, and it paid off. For his bachelor thesis, he developed a new model to better predict an important chemical reaction. ‘On the edge of what is possible at the bachelor level,’ his supervisors write. Thanks to his impressive achievements,…
-
Antibiotics of the future: looking for a new way to kill bacteria
Current antibiotics only address very few target proteins in bacteria to kill them. Researchers know that there are more possible target proteins to tackle the bacteria. The question is: which ones. Thanks to the NWO Vidi Grant, Assistant Professor Molecular Physiology Stephan Hacker and his team can…
-
Treatment before patients develop rheumatism provides lasting relief
Early treatment benefits patients who have not fully developed rheumatoid arthritis but are in the preliminary stages of the disease. This is what researchers from the Leiden University Medical Centre (LUMC) have reported in The Lancet. Patients in the pre-arthritis stage who were temporarily prescribed…
-
Leiden researchers join forces against tuberculosis
About one and a half million people worldwide die each year from tuberculosis. For thirty years, therapy with antibiotics has been the same, while it takes far too long and can lead to resistant pathogens. Leiden researchers from four institutes are now joining forces to develop more effective and efficient…
-
First MIRI-image by the James Webb Space Telescope
The alignment of the James Webb Space Telescope is complete. The space observatory is able to capture sharp, well-directed images with each of its four powerful scientific instruments on board. The MIRI instrument, on which Professor of Molecular Astrophysics Ewine van Dishoeck also worked, was the…
-
Help your students: offer extra support with the skills platform
A new course is often challenging enough for students. But in addition to the new subject matter, they also face all kinds of additional challenges: how do I write a report, how do I find reliable sources, or how do I pitch a research proposal? The e-learning skills platform offers an online learning…
-
Leiden University Global Fund grants 14 project proposals
On 9 December, a lottery to conclude the first call of the Leiden University Global Fund (LUGF) Seed Fund has granted 14 project proposals €15.000. These projects will be working to enhance the relationship between Leiden University and her partners in Africa, Latin America, North East and South East…
-
Leiden resident Ewine van Dishoeck wants to give something back to the city
In 2022, Leiden will be the European City of Science. The preparations are in full swing, so we would like to give you a look behind the scenes. This time we talk to Ewine van Dishoeck. She is the driving force behind the annual programme at the Faculty of Science. As far as she is concerned, there…
-
Article from 1984 remains a hit: citation count passes 10,000
It was already the most cited publication ever written at our faculty, but now a new milestone has been reached. Last month, a paper by emeritus professor Jan Reedijk and his co-authors surpassed 10,000 citations — and the count keeps rising.
-
Six Leiden researchers receive ERC Starting Grant
Six researchers from Leiden University have received an ERC starting grant. This grant of on average 1.5m euros will enable the researchers to launch their own project, form their own research team and develop their best ideas.
-
How fungi are helping us be more sustainable
Professor of Fungal Genetics and Biotechnology Arthur Ram explains how fungi can help us be more sustainable.
-
Inspired teaching without the administrative hassle
In his inaugural lecture Dennis Claessen will explain how he wants to ensure that lecturers have less admin to do.
-
Huge boost for electron microscopy thanks to NWO grant
Leiden University, together with Utrecht University, the LUMC and 10 other Dutch universities and institutes, has been awarded a grant of more than €30 million in the NWO call Roadmap Large-scale Scientific Infrastructure (GWI).
-
Three innovative research projects awarded Open Competition Science-M funding
Tracking mucus-eating bacteria, mapping the complexity of planetary nebulae and a signalling pathway in cancer. These three Leiden projects have been awarded Open Competition Science-M funding by the Dutch Research Council.
-
Madouc Bergers made her own enzyme inhibitors for her bachelor’s thesis
For her bachelor’s thesis, Molecular Science and Technology student Madouc Bergers synthesized her own molecule that can inhibit the breakdown of sugars. Although most students do not even manage to make one building block, Madouc made three. Partly because of this, she has been nominated for the Science…
-
Medical Delta AI for Computational Life Sciences
The fact that scientists are increasingly better able to access molecular cell and tissue data also brings with it a new challenge: how can scientists find the information they need for research among the vast amount of data available?