Helma de Jong

Leiden PhD candidate Mona Shahab climbed Mount Everest two years ago to raise money for the education of disadvantaged children in Egypt. She made it to the top and posed there with the University flag. She recently presented the flag to Rector Carel Stolker.

A CT scanner to treat eye cancer, energy-efficient software for the future and a test to identify male chick eggs. Three projects by researchers from Leiden University are to receive funding from research funder NWO’s Open Technology programme, to which the business sector also contributes.

Three fundamental research projects at Leiden in physics, chemistry and medical science have received funding from the Dutch Research Council (NWO). They involve research on magnetic fields in the universe, the role of myeloid cells in cancer immunotherapy and the evolution of ancient proteins.

Providing each cancer patient with the right treatment remains a challenge. Oncode Accelerator aims to change this by innovating the way we develop cancer treatments, thus ensuring the patient is at the heart of the process.

The supermassive black hole at the center of the Circinus galaxy is being fed with gas by two spiral arms. This is what PhD candidate Wout Goesaert discovered. But only a small percentage disappears into the black hole, the rest is ejected.

A team of international researchers led by Tomas Stolker in the Netherlands has imaged a young gas giant exoplanet near a 12-million-year-old star. The planet is orbiting a star at which planet formation has finished, while the same-aged companion star still has a planet-forming disk. The researchers…

In the disk surrounding the young star WISPIT 2, not one but two planets are taking shape. Leiden PhD candidate Richelle van Capelleveen played a key role in this discovery, providing a rare glimpse into the early stages of planetary system formation.

From painful joints to intense fatigue: a third of rheumatism patients suffer serious effects from this chronic condition and rely long-term on medication. Leiden psychologists are to receive a subsidy from the Netherlands Arthritis Foundation to investigate whether placebo techniques can help patients…

The doctor suggests opting for a treatment that is better for the environment. How do patients react to this? Doctors and psychologists together discovered that this has little impact on patient confidence in the doctor.

A cancer pill, preferably without severe side effects, is something we’d all welcome. Is it a matter of time before such a pill is a reality? We put this question to three Leiden researchers and asked how they themselves are contributing to new cancer treatments.

Astronomers have captured a new deep field of Pandora's Cluster (Abell 2744) with the James Webb Space Telescope. The images show never-before-seen details. The results are described in four scientific papers. Leiden astronomers Marijn Franx and Mariska Kriek collaborated on the study. 'This opens a…

Working in a laboratory is different from working in an office. Some of the rules that apply when working in or around a laboratory are given below.

Researchers from the Leiden University Medical Center (LUMC) have successfully used stem cell gene therapy to treat a baby with the severe congenital immune disorder SCID. An important milestone: it is the first time stem cell gene therapy of Dutch origin has been administered to a patient, and also…

If doctors could better estimate a patient's chances of survival, this would help in choosing a specific treatment. It would be particularly beneficial for the rare and malignant Ewing sarcoma, which mainly affects children and adolescents. Mathematics professor Marta Fiocco has been awarded a substantial…

As technology transforms healthcare and services come under mounting pressure, one question remains the same: Will the advice or treatment offered help patients lead the lives they want to live? In her inaugural lecture, Professor Maxime Kummeling stresses the importance of quality.

Jasper Knoester startte op 1 januari als onze nieuwe decaan. Hoe gaat het met hem, wat doet hij precies en hoe ziet zijn dag eruit? In elke nieuwsbrief geeft Jasper een inkijkje in zijn leven als decaan.

In the Netherlands, 1.55 million people suffer from cardiovascular diseases. Yet, acute cardiovascular events, such as a heart attack or stroke, often occur unexpectedly. That is because many people do not know they are at risk for such an event. Immunological researcher Amanda Foks and her colleagues…

Could we stop cancer cells by cutting off their energy supply? That’s what Dione Blok, a bachelor’s student in Bio-Pharmaceutical Sciences, aimed to find out during her thesis research. She investigated a compound that affects the tumour cells’ energy metabolism. ‘Hopefully, these insights will provide…

The more data from cancer research we pool, the better we can search for new treatments. But how can we keep patient data safe when sharing it? Leiden researchers will tackle this challenge in a major European project.

One in two people will be diagnosed with cancer. World Cancer Day on 4 February raises awareness of the impact of this devastating disease. Leiden University is conducting various studies aimed at preventing and controlling cancer. Below are just a few examples.

The antibiotic EVG7, developed in Leiden, has proven capable of fighting the dangerous gut bacterium C. difficile with only a minimal dose. What’s more, the bacterium is far less likely to return, a major issue with existing antibiotics. The research was published in Nature Communications.

Nerve pain is one of the most common side effects of chemotherapy. It is therefore one of the biggest reasons for cancer patients to stop treatment early. Darcy Reynolds worked on new drug candidates against this pain during her bachelor's thesis. She developed a new series of molecules that increase…

Statistician Anja Rüten-Budde has won the C.J. Kok Jury Award 2020. Her PhD thesis resulted in an app which helps patients with soft tissue sarcoma and their doctors to make well-considered choices about the treatment. ‘Her work is interdisciplinary and directly relevant for society,’ the jury state…

One of our PhD candidates at the LACDR, Joey Zuijdervelt, recently achieved recognition by winning the first prize in the ‘Schild-De Groen Onderzoeksprijzen’ for cancer research. His award-winning master’s thesis explored glioblastoma multiforme through an innovative orthotopic zebrafish xenograft model,…

As part of the ZonMW Antibiotics resistance funding program, the LACDR cluster Systems Pharmacology was awarded €455.255 for a research project to develop novel clinical biomarkers for bacterial infections.

Last month, the European TIPAT ITN network on personalized antibiotic treatments coordinated by Coen van Hasselt had its first in-person meeting. Two years since the project started, all TIPAT PhD candidates and their supervisors from six European universities came together in Leiden.

A widely publicized research article in Nature Metabolism by scientist from the University of Pittsburgh, suggests a high protein diet which is popular among for instance fitness enthusiasts, may be harmful to the cardiovascular system. National media outlets such as NRC Handelsdagblad and NPO 1 Radio…

The transcription factor MYC is a master regulator implicated in the majority of human cancers. Despite its central role, MYC has long been considered "undruggable" by small molecules, lacking binding pockets and featuring disordered regions. While larger biomolecules could potentially disrupt MYC function,…

To inhibit proteins that contribute to the growth of aggressive cancer cells, that’s the plan of Professor Bob van de Water and his team. They will receive over 700,000 euros from the KWF Dutch Cancer Society for their research. Researcher Maaike Vreeswijk and pathologist Danielle Cohen are affiliated…

A Dutch consortium has received €6.7 million to accelerate the development of nanomedicines together with patients. Researchers from Leiden University play a key role in the project.

Five consortia within the Perspectief programme that include Leiden researchers have received funding to start their research projects. These projects focus on (further) developing technological innovations, with societal and economic impact at their core.

One discovered that arteriosclerosis resembles an autoimmune disease, while the other developed a system to aid in the search for new medications. For these achievements, Marie Depuydt and Jurren de Groot were awarded the Krijn Rietveld Memorial Innovation Award on the evening of Tuesday 4 June.

Organs and tissues grown in the lab may in the future be able to cure people with organ failures. Micha Drukker, professor of Stem Cells, Developmental Biology and Technology for Innovative Drug Research, is convinced that the use of stem cells will make this possible. He will deliver his inaugural…

Is it a coincidence that three chemists from the same department have each independently received a ZonMw grant? 'No,' the researchers agree in unison. 'The role of chemistry in medical biology is becoming increasingly important, and we’ve worked hard to make this happen.'

The Dutch Research Council (NWO) has awarded Vidi grants to Leiden researchers.

Only one in five young people with emotional health problems such as an anxiety disorder receives appropriate professional help. GPs often fail to properly recognise the signals in children and young people, according to psychologist Semiha Aydin. How can we improve this? PhD defence 23 February.

Mathematics can help predict thrombosis. Mathematician Mark Alber has developed models that even aid in suggesting treatments. In the Kloosterman lecture on 27 June, he will explain how this works.

When a bacterium becomes more resistant to one antibiotic, it sometimes becomes more sensitive to another. To better understand this interaction, researchers from the Leiden Institute of Biology (IBL) and the Leiden Academic Center for Drug Research (LACDR) under supervision of Daniel Rozen and Coen…

The promising early results of an international study have shown that insulin-producing cells grown from stem cells can cure the disease. The new Cure One LUMC research centre aims to accelerate this breakthrough.

The Leiden University Medical Center (LUMC), the Danstem Institute from the University of Copenhagen and the Murdoch Children’s Research Institute in Melbourne have received 300m euros from the Novo Nordisk foundation. The aim of this new international consortium is to bring stem-cell based therapies…

Biophysicist Alireza Mashaghi and his collaborators are taking up the fight against muscular dystrophy: genetic disorders that cause muscle weakness. They want to inhibit the clumping of proteins that results in toxic aggregates. For this, the team receives 550,000 euros from Health Holland. The team…

Biological chemist Nathaniel Martin and his team received an NWO grant to examine how blocking a specific enzyme in our body, NNMT, could be helpful in the treatment of some cancers. Trials with mice have been promising, and together with the Netherlands Cancer Institute, Martin wants to take the next…

Four Leiden researchers have been awarded Proof of Concept grants by the ERC. These grants, each worth 150,000 euros, help researchers translate the findings of previous ERC projects into innovative practical applications.

Funded by a ZonMw grant, the LUMC and the Health Campus The Hague will be working with headache patients on research into the use of an electronic headache diary. This resource can help patients gain a better understanding of their migraine attacks and, together with the physician, produce the best…

Bringing your drug candidates to patients is what many academic chemists dream about, but the road to this goal is long and bumpy. Now, Leiden small molecule nizubaglustat is ready for phase 3 clinical trials. This is thanks to a €132 million funding secured by the biotech spin-out Azafaros.

The Dutch Research Council (NWO) has, within the framework of Research along Routes by Consortia (NWA-ORC), awarded the research project Next Generation Immuno-Dermatology (NGID) with a prestigious grant of 11.7 MEuro. NGID is a nationwide, large-scale project to unravel novel biomarkers for six different…

Bacteria whirl around in the mouths of most people, forming dental plaques and sometimes causing nasty gum infections. Treponema denticola might be a dangerous pathogen, but not much is known about this bacterium. It was up to Ariane Briegel and her research group to change that.

Researchers have discovered the most distant Milky-Way-like galaxy yet observed. Dubbed REBELS-25, this disc galaxy seems as orderly as present-day galaxies, but we see it as it was when the Universe was only 700 million years old. This is surprising since, according to our current understanding of…

Astronomers led by Leiden PhD candidate Richelle van Capelleveen have, for the first time, discovered an exoplanet that has carved a bright gap in the protoplanetary disc around its star. This rare observation provides new insights into how young planets shape their surroundings.