619 search results for “lipid chair length” in the Public website
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statistics disagree: two frequentist challenges for the minimum description length principle
Promotor: P.D. Grünwald
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Cleveringa chair
The Cleveringa chair was installed by Leiden University in memory of Professor Rudolph Pabus Cleveringa and the courage he demonstrated in November 1940 during the German occupation . It also commemorates the liberation of the Netherlands in 1945.
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Exploring the potentials of nurture: 2(nd) and 3(rd) generation explant human skin equivalents
BACKGROUND: Explant human skin equivalents (Ex-HSEs) can be generated by placing a 4mm skin biopsy onto a dermal equivalent. The keratinocytes migrate from the biopsy onto the dermal equivalent, differentiate and form the epidermis of 1(st) generation Ex-HSEs. This is especially suitable for the expansion…
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Pascal chair at LIACS
The Leiden Institute of Advanced Computer Science (LIACS) of Leiden University proudly establishes the Blaise Pascal chair. The chair applies for one year and is meant to strengthen the cooperation of the Leiden computer science research with foreign institutes.
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Pascal chair 2023
Peter Flach is Professor of Artificial Intelligence at the University of Bristol. An internationally leading scholar in the evaluation and improvement of machine learning models using ROC analysis and calibration, he has also published on mining highly structured data, on knowledge-driven and explainable…
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EU Chair Holder
Irma Johanna Mosquera Valderrama is Full Professor Global Tax Governance, EU Holder Jean Monnet Chair EUTAXGOV at Leiden Law School (Leiden University), the Netherlands and Lead Researcher of the European Research Council (ERC) Funded Project – GLOBTAXGOV.
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The role of lipids in the barrier function of the skin
The outermost layer of the skin, the stratum corneum (SC), is responsible for the skin barrier function, protecting the body from pathogens, chemicals and other unwanted substances from the external environment. The SC lipid matrix provides the only continuous pathway through the SC and is considered…
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Jean Monnet Chair of Moritz Jesse
Moritz Jesse has been awarded a Jean Monnet Chair by the European Commission. In his MIND-EU Project he will focus on a coherent way to teach Migration, Integration, and Non-Discrimination at Leiden Law School at bachelor and master level.
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Van der Heijden Chair Social Justice
On the occasion of prof Paul van der Heijden’s stepping down as Rector Magnificus and President of the Executive Board of Leiden University in 2013 the Chair bearing his name on Social Justice was established. It was a “farewell present” of the Leiden University to it’s Rector.
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Noëlle van EgmondFaculty of Science
n.van.egmond@lic.leidenuniv.nl | 071 5272727
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UNESCO Chair on Diversity and Inclusion in Global Science
This UNESCO Chair at CWTS aims to contribute to UNESCO’s agenda to foster diversity and inclusion in science. The chair has two main lines of work:
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Karwan Fatah-Black appointed as UNESCO Chair holder
Karwan Fatah-Black, a historian at Leiden University’s Faculty of Humanities and senior researcher at the KITLV/Royal Netherlands Institute of Southeast Asian and Caribbean Studies, has been appointed as the UNESCO Chair holder in Comparative History of Slavery and the Transition to Citizenship.
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Chair Kingdom Relations: Democratic Representation in the Kingdom
The Chair Democratic Representation in the Kingdom focuses on the political relations between the ‘European’ Netherlands and the six Caribbean islands in the Kingdom; so-called Kingdom Relations. Professor Wouter Veenendaal investigates the quality of democratic representation in the Kingdom, both within…
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Oscar Escalona RayoFaculty of Science
o.escalona.rayo@lic.leidenuniv.nl | 071 5272727
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A Model Membrane Approach to Elucidate the Molecular Organization in the Skin Barrier
Promotor: J. A. Bouwstra
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A novel formulation for skin barrier repair : from ex vivo assessment towards clinical studies
The stratum corneum is the outermost skin layer and consists of dead cells embedded in a lipid matrix.
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Chair of UN Studies in Peace and Justice
From 1 August 2018, Alanna O'Malley was appointed as Chair of United Nations Studies in Peace and Justice, focusing on the ‘lesser-known actors’ of the UN: women, the youth, the agents of informal diplomatic networks within the UN and actors from the Global South. This Special Chair has been created…
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An ex vivo human skin model for studying skin barrier repair
In the studies described in this study, we introduce a novel ex vivo human skin barrier repair model. To develop this, we removed the upper layer of the skin, the stratum corneum (SC) by a reproducible cyanoacrylate stripping technique.
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Yifan WangFaculty of Science
y.wang.137@liacs.leidenuniv.nl |
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LUMC researchers: high levels of lipids in blood protect against allergies
People with relatively high levels of lipids in their blood are less likely to develop allergic conditions such as eczema and asthma. These lipids cause genes that play a key role in allergic reactions to be less active. Researchers from the Leiden University Medical Center (LUMC) have published an…
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Photocontrol of Transmembrane Anion Transport
Anionic particles play an important role in biological systems where they fulfil many essential functions for cells.
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Dyslipidemia at the crossroad of the skin barrier and the arterial wall
The research described in this thesis shows that hypercholesterolemia, a well-established risk factor for atherosclerosis, can impact skin lipid pool and barrier function already at young age. In the field of atherosclerosis, we showed that the small peptide Lyp-1 can be used as a targeting molecule…
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Thermostable Nanodiscs for the development of novel biopharmaceuticals
Nanodiscs are small, disc-shaped structures designed to mimic biological cell membranes, composed of a lipid bilayer stabilized by scaffold proteins. Membrane proteins play crucial roles in essential processes such as nutrient and waste transport, molecular recognition, and cell signalling, making them…
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Discrete tomography with two directions
Promotores: R. Tijdeman, K.J. Batenburg
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Research lines
Current research at the Skin Barrier and Vaccination group.
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Professor and Knight: Joke Bouwstra Receives Royal Honor
A memorable farewell symposium and a royal distinction: Professor Joke Bouwstra could not have completed her career at Leiden with more pleasure. On Friday, 14 June, she received a Royal Honor from Leiden Mayor Peter van der Velden, who appointed Bouwstra as a Knight in the Order of the Dutch Lion for…
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Nanoparticles and Microfluidics for Future Tuberculosis Vaccines
Tuberculosis is a major global health problem caused by the Mycobacterium tuberculosis complex, claiming more than a million lives annually.
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Evolutionary molecular dynamics
This thesis introduces the concept of
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In vitro and in vivo delivery of functionalized nanoparticles via coiled-coil interactions
Promotor: A. Kros, Co-promotor: R.R.C.L. Olsthoorn
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Cholesterol metabolism in mouse models of atherosclerosis and adrenal steroidogenesis
Cholesterol influences many pathways, including serving as precursor for adrenal steroidogenesis. Imbalance of cholesterol levels has been implicated in several diseases including cardiovascular diseases and its underlying pathology, atherosclerosis.
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New Owada chair in Leiden and Tokyo
The universities of Tokyo and Leiden are installing a rotating chair named after Professor Hisashi Owada. The Owada chair will focus on interaction between international law and international relations through interdisciplinary approaches. Dominique Moïsi, a professor at King’s College in London, will…
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Launch Owada Chair
On 24 May 2022, the universities of Tokyo and Leiden organized a rotating chair named after Professor Hisashi Owada. The Owada Chair focused on the interaction between international law and international relations in an interdisciplinary perspective. Dominique Moïsi, a professor at Kings College London…
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Manchu ThangaveluFaculty of Science
m.u.thangavelu@lacdr.leidenuniv.nl | 071 5272727
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Sander WezenbergFaculty of Science
s.j.wezenberg@lic.leidenuniv.nl | 071 5274541
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New Kikkoman chair in Leiden
The Kikkoman chair is a new chair in Leiden sponsored by the Kikkoman Foundation and the Association of Friends of Asiatic Art. The chair will address the intercultural dynamics of Asia and Europe.
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Impaired barrier of inflammatory skin diseases
Focus in skin research
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Travelling through the body with graphene
For the first time researchers have succeeded in placing a layer of graphene on top of a stable fatty lipid monolayer. Surrounded by a protective shell of lipids, graphene could enter the body and function as a versatile sensor. The results are the first step towards such a shell, and have been published…
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Microengineered Human Blood Vessels For Next Generation Drug Discovery
Heart failure is a major health care problem with high mortality.
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Novel factors modulating AGC kinase signaling-controlled polar auxin transport
The PID-directed shift in PIN polarity has been broadly accepted as one of the essential mechanisms for the regulation of auxin transport polarity.
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Mesoporous silica nanoparticle-based protein delivery systems for biomedical applications
Promotor: A. Kros
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Survival of the Littlest: Improving Preterm Outcomes through Metabolomics and Microsampling
Preterm birth is a major contributor to neonatal morbidity and mortality and is associated with both acute complications and long-term health consequences.
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Owada Chair should bring together nations, cultures and individuals
Dominique Moïsi, a professor at King’s College London, will be the first holder of the Owada chair. ‘In the present international context of polarisation and divisions within societies and amongst nations, any effort at bringing Asia and Europe closer to each other is truly important.’
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Freya Baetens awarded Francqui Chair
Freya Baetens, Professor of European Law, has been awarded a Chair by the Francqui Foundation in Belgium for the impact of her work on lawmaking and policymaking in Europe and beyond.
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The Role of Linker DNA in Chromatin Fibers
The genetic information of all living organisms is contained in their DNA. Cells modify the degree of DNA compaction by epigenetics, which largely determines what genes are read out and which genes are transcriptionally silent.
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Skin Barrier and Vaccination
The Skin Barrier and Vaccination group is led by Prof. Joke Bouwstra. One of the key functions of the skin is its barrier function, which is located in the uppermost layer of the skin, the stratum corneum. The stratum corneum consists of enucleated dead cells (corneocytes) embedded in a lipid matrix.…
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A novel biofilm for skin barrier repair of patients with atopic eczema
Atopic eczema is a skin disease with increasing incidence currently affecting 25% of the paediatric population. In atopic eczema the skin barrier function is reduced. This barrier is formed by the outermost layer of the skin called the stratum corneum (SC). The SC consists of terminally differentiated…
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Karolina Pomorska awarded Jean Monnet Chair
Political scientist Karolina Pomorska (Institute of Political Science, Leiden University) has been awarded a Jean Monnet Chair. The aim of her chair, entitled The EU and the World, is to promote and strengthen teaching and research in European Studies in Leiden and in The Hague.
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Fourth Session of the Owada Chair
The University of Tokyo hosted the 2024 edition of the Owada Chair. GTGC's Prof. dr. Jan Aart Scholte and Prof. dr. Eric De Brabandere attended the session in representation of Leiden University.
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Anjali PanditFaculty of Science
a.pandit@chem.leidenuniv.nl | 071 5274198