The guardian of our genome, the protein MutS, scans the DNA for spelling errors and makes sure they are corrected. An essential process for our health. Researchers at Leiden University Medical Centre (LUMC) have discovered precisely how this protein works by making MutS visible with cryo-electron microscopy.…

BRAIN Biotech and the Leiden University will jointly develop an Aspergillus based production strain with high yield and thus contribute to a bio-based circular economy. The cooperation is based on BRAIN´s molecular tool BEC.

Imagine scanning lion dung or a mouse dropping and instantly knowing exactly what and how much the animal has eaten. Thanks to new DNA techniques, this is becoming increasingly feasible. PhD student Kevin Groen tested how effective these techniques are at unraveling the diets of wild animals.

To eat or get eaten. It describes the evolutionary race of snakes versus the mammals and birds that prey on these snakes. Muzaffar Ali Khan devoted his PhD to investigating the molecular mechanisms play of the evolutionary arms race, and has his promotion 16 February. What makes mammals and birds successful…

Sander van Kasteren (Professor of Molecular Immunology) makes the invisible visible. He will explain more in his inaugural lecture.

Seven Leiden professors have been elected as members of the Royal Netherlands Academy of Arts and Sciences (KNAW). In total 23 new members will be inaugurated on Monday 13 September.

For over a year now, the James Webb Telescope has been sending stunning images that exceed astronomers’ expectations. The photos are fascinating to see, but what exactly are we looking at? Assistant professor Melissa McClure explains.

How do you fulfill a chairing position during a team meeting? How do you visualise a dataset for a presentation? How do you write the introduction to a scientific article? All Science students can find the answers to these and many more questions in the 100+ skill modules on the digital Science Skills…

Emeritus Professor of Molecular Astrophysics Ewine van Dishoeck has been named a Citation Laureate by Clarivate, a research analytics provider. Clarivate considers her an influential researcher of the calibre to win a Nobel Prize.

During the LACDR Fall Symposium, Niek Kijk in de Vegte received the annual Suzanne Hovinga Award for the best master thesis. Niek performed his RP1 research under the supervision of Dr. Natalia Ortiz Zacarias and Prof.dr. Laura Heitman in the Molecular Pharmacology group at the Division of Drug Discovery…

During the LACDR Fall Symposium, Daan Jiskoot received the annual Suzanne Hovinga Award for the best master thesis. Daan performed his Research Project 2 at the University of California, Irvine at the Prof. David Mobley lab, supported by LACDR supervisor Willem Jespers. The in silico determination of…

Yeast, alpacas, and antibodies. They may seem unrelated, but within the project of the Leiden iGEM students, they come together perfectly. For the international synthetic biology competition iGEM, the team is working on an innovative method to produce nanobodies—a special form of antibodies—using brewer’s…

What started as an idea during a social gathering led to an unexpected breakthrough in research on resistant bacteria. Biologists and chemists from Leiden developed a new substance that proves to be effective against bacteria resistant to antibiotics. They published their discovery in Nature Chemist…

With the aid of physics and a minuscule magnet, researchers have discovered a new structure of telomeric DNA. Telomeres are sometimes seen as the key to living longer. They protect genes from damage but get a bit shorter each time a cell divides. If they become too short, the cell dies. The new discovery…

Plant biologist Pingtao Ding, assistant professor at the Institute of Biology Leiden (IBL), has received a 2.4 million European grant from the European Research Council (ERC). This ERC Starting Grant for promising young researchers allows him to unravel the molecular mechanisms by which plants resist…

The Fritz Zwicky Prize 2022 for Astrophysics & Cosmology has been awarded to Prof. Ewine F. van Dishoeck for her pioneering, decades-long work in astrochemistry and molecular spectroscopy, as well as for her leadership within the astronomical community. The award was announced today by the European…

How do you engage students? Sander van Kasteren knows how to do that like no other. ‘He compares immune cells to Pokémon and doesn’t just give information; he tells stories,’ students say about their favourite lecturer, Sander van Kasteren. The Professor of Molecular Immunology passionately teaches…

Smart drug carriers, uneven cosmic expansion, and solar energy storage in molecules. These are the topics of three newly awarded NWO-XS grants to researchers at the Faculty of Science.

One of our RISE members, Prof. Laura Heitman, has been nominated for the TOPX Females to Follow “Guiding Star” award. TOPX empowers promising and ambitious women, and aims to honour inspirational females with remarkable careers in Life Sciences. TOPX selected her (and 7 other female professionals) because…

For the second year in a row, LACDR organized an international symposium on molecular fold topology. An afternoon program centered around the theme “circuit topology”, inspired and connected mathematicians, physicists and chemists. Scientists from USA, Europe, and Asia participated in this online ev…

From 1 October, two new Directors of Education will start at the Institute of Biology Leiden (IBL). Dennis Claessen as the new director for the master's programme of Biology and Marcel Schaaf as director for the Biology bachelor's programme. Claessen and Schaaf have been appointed for a period of four…

What happens in the brains of people with psychiatric illnesses? With a €23.23 million gravity grant, scientists from different fields will search for biological causes over the next decade. ‘By joining forces, we hope to improve diagnosis and treatment for patients with these diseases.’

Researchers at the Universities of Amsterdam (Uva) and Leiden together with the Netherlands Cancer Institute and Oncode Institute have received a €10,6 million ERC Synergy Grant to develop innovative therapeutic approaches to target glioblastoma. This is a deadly primary brain tumour for which no curing…

Is it a coincidence that three chemists from the same department have each independently received a ZonMw grant? 'No,' the researchers agree in unison. 'The role of chemistry in medical biology is becoming increasingly important, and we’ve worked hard to make this happen.'

On the 6th and 7th of September 2023, the Leiden Academic Centre for Drug Research (LACDR) organized the Leiden Bio-AFM workshop in cooperation with Bruker Nano GmbH (Germany) and Bruker Nederland BV. The organization of this event was led by the Medical Systems Biophysics and Bioengineering group (Alireza…

The Rob Schilperoort Memorial will be unveiled at the Leiden Bio Science Park on Saturday 16 September. This gigantic gate stands at the entrance to the park, which is also named after Schilperoort, its founder.

The 'deepest and sharpest' image of the Universe to date: the first photos from the new James Webb space telescope yesterday mesmerised astronomers and the public alike. Leiden Professor of Molecular Astrophysics, Ewine van Dishoeck, spoke to various media outlets about the first images, which include…

As of 1 September, Marco van Eijk has been appointed Director of Education of the bachelor's programme Life Science & Technology. He succeeds Marcellus Ubbink, who moved to the position of Scientific Director of the Leiden Institute for Chemical Research (LIC). Van Eijk has been appointed for a period…

On Tuesday evening 22 August, our very dear colleague Jo Hermans passed away. Jo had been ill for some time, but continued to enjoy life in good spirits until the very end. He meant a great deal to Leiden University and will be remembered with fond memories by many.

Finally we know for sure that there is a black hole at the centre of our own galaxy. Today, astronomers unveiled the first ever photo of Sagittarius A*, a super-massive object at the centre of the Milky Way. This picture could only be taken thanks to the cooperation of telescopes worldwide.

Bacteria carry countless hidden treasures in their DNA: fragments that could hold the key to new medicines. But how do you pick out the most promising ones from millions of options? ‘Look at the switches that turn genes on and off,’ says molecular biologist Gilles van Wezel.

An international team of astronomers led by Ardjan Sturm of the Observatory has made the first two-dimensional inventory of ice in a planet-forming disk of dust and gas surrounding a young star. The researches, including Melissa McClure, used the James Webb Space Telescope and publish their findings…

Three new initiatives will provide a more diverse view of Leiden’s academic history, literally and figuratively: a historical study on the background of students and scientists, a new book about the Academy Building, and two new sculptures of female scientists, Ewine van Dishoek, Professor of Molecular…

To facilitate the search for new antibiotics. That is the aim of Gilles van Wezel, professor molecular biotechnology at the Institute of Biology Leiden (IBL). He wants to do this by looking at similarities in the DNA of antibiotic-producing bacteria. Van Wezel has been awarded an ERC Advanced grant…

Hunter-gatherers acquire their food through complex gender-specific foraging techniques for a relatively stable and diverse supply of energy. New research indicates that this specialisation by boys and girls starts at a very young age. Most likely, this enabled the human species to evolve much larger…

Good research means looking beyond disciplinary boundaries, said Professor of Molecular and Cellular Biochemistry Remus Dame in his inaugural lecture on 10 May. Processes that take place on DNA shouldn’t only be researched in a test tube but also in living cells, for instance.

A single tiny molecule that can destroy flu, corona, HIV and Zika viruses? Yes, it really does exist. Biophysicist Niek van Hilten, who will receive his doctorate on 14 September, contributed to this discovery.

A flu virus could cause a pandemic. And then we would be poorly armed because flu viruses are starting to become resistant to flu medications like Tamiflu. Chemist Merijn Vriends successfully worked on an improved version of such medications. He will be awarded his doctorate on September 12th.

Molecular Science & Technology student Renske Donkers has won the second edition of the Young Star Award. During the ceremony on Wednesday 17 February, no less than three teachers were awarded the title 'Teacher of the Year'. Finally, students had a surprise in store for all teachers: with a video they…

Eight early-career researchers from around the world have been awarded a 51 Pegasi b Fellowship – a prestigious opportunity for astronomers. Julia Santos, a PhD candidate at Leiden Observatory, is one of them. We asked her four questions about this remarkable fellowship.

On October 12th, the LACDR PhD-Postdoc event will be organized in castle Oud Poelgeest.

Sebastian Pomplun manages to reach proteins with drugs even where this was thought impossible. That is why he and his research group have been allowed to join Oncode Institute. With nine others, he had been selected from 72 applicants to contribute to Oncode Institute's mission: to accelerate breakthroughs…

Through its Demonstrator Projects, the Dutch Oncode Accelerator consortium provides grants for preclinical cancer therapy development. The first call for these projects is open until September 2025.