Can small molecule drugs restore the immune system’s ability to fight tuberculosis by boosting autophagy?

The Collective Experience of Empathic Data Systems (CEEDs) consortium developed novel integrated technologies that support experiencing, analysing and understanding of very large datasets.

In this book liposomes are explored as delivery system for allergen-specific immunotherapy. Both cationic and anionic formulations are prepared with Bet v 1, one of the allergens in birch pollen.

Food waste is a defining inefficiency of the modern food system, with profound implications for resource use, climate change, and circular economy transitions. This dissertation examines food waste through two complementary lenses: the prevention of avoidable food waste and the valorization of unavoidable…

Promotor: F.H.J. Redig, Co-Promotor: W.T.F. den Hollander

The first objective is to create a catalogue raisonée, i.e. a structured database that will store the main attributes of each town in a standardized format database, which will be freely accessible when completed; the second objective is to exploit theories and methods that can help us to understand…

On 25 January 2018 Yannick van den Brink defended his doctoral thesis titled ‘Voorlopige hechtenis in het Nederlands jeugdstrafrecht’ (‘Pre-trial detention in the Dutch juvenile justice system’). The doctoral research is supervised by Professor Ton Liefaard and Professor Mariëlle Bruning.

We are developing biology-driven platforms to measure metabolites based on liquid chromatography-mass spectrometry (LC-MS), gas chromatography-MS (GC-MS), and capillary electrophoresis-MS (CE-MS).

Promotor: Prof.dr. M. Ubbink

Exploring the integration of AI and quantum computing, this study adapts Knowledge Representation and Reasoning (KRR) to enhance quantum circuit simulation and optimization.

Inflammatory skin diseases such as psoriasis and atopic dermatitis can severely impact both the physical and social aspect of a patient’s life. Aberrant inflammatory responses are thought to be a major causative factor in these disorders, but an abundance of different factors contribute to the development…

To what extent is the legislation and use of pre-trial detention of juveniles in the Netherlands in compliance with international children’s rights standards?

On 17 December 2018, Dejian Kong defended his thesis 'Civil Liability for Damage caused by Global Navigation Satellite System'. The doctoral research was supervised by Prof. dr. P.M.J. Mendes de Leon.

Generations of Leiden students and academics have done archaeological research into the early medieval history of Oegstgeest. This makes this old settlement one of the best-documented sites from that era. In a new book, Leiden researchers take stock.

This thesis focuses on two processes involved in fighting infections: metabolism and immune cell motility and navigation.

Cardiovascular diseases are the primary cause of death in the world with atherosclerosis as primary underlying cause.

Intelligence of the crowd, or in other words, intelligence of a large, random collective, exists mostly in social media platforms such as twitter. The collective does not comprise (at least not necessarily) experts on crises, just regular people mostly. Nevertheless, there is valuable intelligence to…

DSE 2.0 concerns research on DSE techniques for complex dCPS

This is a study of Plateau Shimakonde, a sub-dialect of the Makonde language which is spoken on the Makonde Plateau in northern Mozambique.

You can ask virtual assistant Siri about the weather, but you can’t have a real conversation with it yet. You can’t refer to anything that’s been said before, or ask the system why it says what it says. Stephan Raaijmakers, Professor by Special Appointment from TNO, hopes to change this.

The research in my group addresses a range of topics related to quantum many-body physics.

The aim of the project is the development of polypept(o)ide-based delivery systems to use siRNA as systemic applicated therapeutic agent against e.g. solid tumors

This project aims to develop a portable, real-time intelligent system tailored for speech disorder therapy.

Promotor: S.M. Verduyn Lunel

Promotores: W.T. de Groot, M. Tchuenté, Co-promotor: J.P. Cheylan

On 24 September 2020, Bernardo Ribeiro de Almeida defended his thesis 'Building land tenure systems: the political, legal, and institutional struggles of Timor-Leste'. The doctoral research was supervised by Prof. A.W. Bedner. Co-supervisor was Dr. C.I.M. Jacobs.

Xinrong Ma defended her thesis on 13 February 2018

On Friday 7 March 2025 Adam Knight successfully defended a doctoral thesis and graduated.

This thesis consists of two main parts. The first part (Chapters 2 and 3) deals with a class of Markov process called Quasi-Skipfree (QSF) processes.

My ERC Starting Grant, funded with €1.5 million for 5 years as part of the Horizon 2020 research and innovation program, is focused on building the early warning system WARN-D to reliably forecast depression in young adults before it occurs. Why depression, and why prediction?

In December 2024, the book Redressing Fundamental Rights Violations by the EU: The Promise of the ‘Complete System of Remedies', edited by Melanie Fink, was published fully open access with Cambridge University Press. The EU prides itself on having created a legal system that puts the individual at…

Growth and development affect the metabolism of drugs administered to neonates, infants, and children.

This is the first special issue of any organisation studies journal on food labour. Why is this a big deal? In this Introduction, we argue that the field should pay much more attention to the agri-food system and the work that goes into producing, distributing and consuming foodstuff. Food is such an…

The focus of this thesis is how stars like our Sun and planets like Jupiter, Saturn, and Earth are formed.

Analysis of drug adversity

The upscaling of Life Cycle Assessment (LCA) data is recognized as one of the main challenges in the ex-ante LCA of emerging technologies. This challenge arises since industrial-scale system specifications for these technologies are unknown and industrial data is lacking.

Students with learning problems experience difficulties in reading, writing, and content-area learning into and throughout their secondary-school years

Using artificial intelligence is more complicated for the government than for companies. Bram Klievink, Professor of Public Administration, aims to identify the problems and find solutions.

Promotor: S.M. Verduyn Lunel

Even though more than 4000 extra-solar planets are known today, only a small fraction of these has been captured in an image. To better understand the planet formation mechanisms in solar-like environments we started the Young Suns Exoplanet Survey (YSES).

Homicide engenders broad moral concerns in society, and its aftermath can be understood as a barometer for criminal justice policy. Of all homicides committed, however, only some lead to arrest, to prosecution and ultimately to conviction in court.

Grasseni's contribution to this special feature on food cultures, food systems, and agriculture in Europe builds upon her ongoing project Food citizens? Collective food procurement in European cities: solidarity and diversity, skills and scale.

Clinical development of drugs for central nervous system (CNS) disorders has been particularly challenging and still suffers from high attrition rates.

Pectin is a plant cell wall polysaccharide made of mainly D-galacturonic acid (GA) subunits. The potency of the filamentous fungus Aspergillus niger to naturally secrete high amounts of pectinases to degrade pectin has been utilized for the industrial production of pectinases.