1,514 search results for “brain functions and dysfunction” in the Public website
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The role of lipids in the barrier function of the skin
The outermost layer of the skin, the stratum corneum (SC), is responsible for the skin barrier function, protecting the body from pathogens, chemicals and other unwanted substances from the external environment. The SC lipid matrix provides the only continuous pathway through the SC and is considered…
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Inventing anchors? The function of ‘Greek models’ within the process of innovation in Early Roman Drama
To what end and how does Plautus constantly underline the Helleni(sti)c provenance of his art? How does this aspect relate the author’s originality?
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Cognitive control in context: Neural, functional, and social mechanisms of metacontrol.
To argue that people can control the relative contributions of goal-driven and stimulus-driven processes to decision-making and action selection.
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Form and Function in Greek Grammar. Linguistic Contributions to the Study of Greek Literature
Form and Function in Greek Grammar. Linguistic Contributions to the Study of Greek Literature is a new book, written by Albert Rijksbaron. Rijksbaron is internationally known as one of the leading scholars of the Ancient Greek language, whose work has exerted a strong and lasting influence on the scholarly…
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persistence of space: formalizing the polysemy of spatial relations in functional elements
On the 20th of June, Camil Staps successfully defended a doctoral thesis. Leiden University Centre for Linguistics congratulates Camil on this achievement!
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Functions of leptin in tuberculosis and diabetes: multi-omics studies across species
In this thesis, I study 1) metabolic alterations in tuberculosis related to wasting syndrome in human patients as well as in rodent and fish animal models. 2) effects of the mutation of the leptin gene on cachexia and diabetes in rodent and zebrafish animal models.
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Functionalizing monolayer graphene as a proton-selective membrane for direct methanol fuel cells
This thesis focused on the exploration of monolayer graphene as a membrane in direct methanol fuel cell (DMFC) applications, with improvements achieved through plasma exposure or damage- free chemical functionalization.
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Metabolism and Lipid Mediators as Regulators of Innate Immune Cell Function
PhD defence
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Double inaugural speech: how social context influences processes in the brain
It’s not a regular occurrence at Leiden University: two professors giving their inaugural lecture on the same day. Berna Güroğlu and Ellen de Bruijn specialise in related disciplines: they both research the influence of social context on processes in the brain – Güroğlu in adolescents and De Bruijn…
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Language and self-regulation in XXY
The role of language in self-regulation and social behavior in children with an extra X chromosome
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house or birdhouse? Research on compounds gives insight into how our brain works
When we hear the word ‘bird house’, do we process it as a whole or does our brain see it as ‘bird’ and ‘house’? PhD student Jiaqi Wang explored this for speakers of Mandarin Chinese.
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Physics and Engineering Approaches to Biomedicine and Pharmacology
Mashaghi lab conducts research at the interface of physics, engineering and biomedicine. We develop and use theoretical and experimental approaches to address basic and applied research problems.
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Research lines
Physics and Engineering Approaches to Biomedicine and Pharmacology
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Research
The Institute of Psychology is responsible for innovative and interdisciplinary research and education within psychology and related disciplines.
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Finally solved: how the body's own marijuana spreads through the brain
Since its discovery thirty years ago, it remained a mystery: how does the body’s own marijuana move between nerve cells in the brain? Mario van der Stelt and his research group have now uncovered the answer. This insight could aid the development of new treatments for pain and neurological disorders…
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Dietsje JollesFaculty of Social and Behavioural Sciences
d.d.jolles@fsw.leidenuniv.nl | 071 5272727
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Nuclear Quantum Effects in Solid Water
Ice, the solid state of water, plays an important role on our planet as well as the entire universe.Despite the fact that an individual water molecule has a very simple structure, its chemical bonding in the solid phase can be surprisingly complex.
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Child abuse from generation to generation: what role does the brain play?
‘We didn’t find any mechanisms in the brain for transmitting child abuse from generation to generation. What we did find is that experiences of neglect and abuse affect the brain differently,’ concludes Lisa van den Berg (Clinical Psychology). PhD defence 30 June.
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Lukas KunzFaculty of Social and Behavioural Sciences
l.kunz@fsw.leidenuniv.nl | 071 5272727
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Hinke EndedijkFaculty of Social and Behavioural Sciences
h.m.endedijk@fsw.leidenuniv.nl | 071 5271435
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Natural brain opioids help us “see the bigger picture” after rewards
Feeling good doesn’t just lift our mood—it also helps us stay flexible and resilient. A new study by an international team of neuroscientists shows that natural brain opioids released after rewards play a key role in broadening attention, offering fresh insights into stress, cognition, and well-bein…
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Daredevil behaviour of young people due to active reward centre in the brain
Young people tend to take more risks than children or adults. This trend is related to the reward centre in the brain, which is much more active when they are rewarded, PhD candidate Barbara Braams discovered. Personality, testosterone levels and social context also play a role in risk-taking.
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Doctors discover a simple method to predict the risk of brain tumour recurrence
The risk of a brain tumour recurring can be predicted more accurately by counting the number of immune cells in the tumour under a microscope. These are the findings from research conducted by LUMC, Erasmus MC and Heidelberg University.
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Berna GürogluFaculty of Social and Behavioural Sciences
bguroglu@fsw.leidenuniv.nl | 071 5272727
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Me, My Fiends, and I
A neuro-ecological perspective on adolescent prosocial development
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A look at music in the brain at the LIBC public symposium
How does music affect a test subject’s brain? That was just one of the questions on the minds of the people who came to the LIBC public day to hear Rebecca Schaefer’s talk, as well as to hear from other top researchers about their investigations into music. The five woodwind players in the Calefax reed…
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Reinoud Kaldewaij awarded Veni grant to measure brain and body reactions to touch
Part of our social contact is currently online, with no physical proximity. Does digitalisation mean that we are losing an effective way of making contact with one another? This is what Reinoud Kaldewaij will be studying with a Veni subsidy from the Dutch Research Council (NWO). 'An issue that will…
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may have made the essential difference in the evolution of our huge brain
Hunter-gatherers acquire their food through complex gender-specific foraging techniques for a relatively stable and diverse supply of energy. New research indicates that this specialisation by boys and girls starts at a very young age. Most likely, this enabled the human species to evolve much larger…
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Bibi van den Berg about the Dutch brain drain in Cyber security
Bibi van den Berg, Professor of Cyber Security Governance at the Institute of Security and Global Affairs (ISGA), has been interviewed by Financieel Dagblad (FD) and BNR Nieuwsradio about the considerable shortage of cyber security specialists in the Netherlands. Van den Berg warns of a brain drain,…
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Review paper on the potential impact drug-metabolizing enzymes on brain exposure
PhD candidate Mengxu Zhang (Division of Systems Pharmacology and Pharmacy) published a comprehensive and important review on “The potential impact of CYP and UGT drug-metabolizing enzymes on brain target site drug exposure” in Drug Metabolism Reviews.
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NWO grant for early dementia detection
NWO honoured Leiden psychologist Jeffrey Durieux with a Research Talent Grant for early dementia detection by identifying differences in resting-state networks.
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Destroy, Create, Transform and Sublimate. Laboratory Dissociation Studies on Polycyclic Aromatic Hydrocarbons and Analogues
The aromatic infrared bands (AIBs) seen throughout the interstellar medium (ISM) are generally thought to be carried by polycyclic aromatic hydrocarbons (PAHs) and their nitrogen analogues (PANHs).
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Microbial footprints of tomato domestication
Although plant domestication has significantly altered crop genetics and phenotypes, its effects on the taxonomic and functional diversity of plant-associated microbiomes are not well understood.
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Career prospects
A master's degree in Psychology at Leiden University combines theoretical knowledge with academic and professional skills, making you an attractive candidate for many employers.
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Quantum computing, norms and polynomials
In this thesis, Quantum computing, norms, and polynomials, we investigate the interplay between quantum mechanics, complexity theory, and functional analysis, three central areas of physics, computer science, and mathematics, respectively.
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Bruijn: ‘Hormonal fluctuations in women have been ignored for too long in brain research’
Psychologist Ellen de Bruijn studies the effects of hormonal fluctuations on behaviour and on the brain over a woman's life course. With an ERC Consolidator grant, she and 3 PhDs and a postdoc will further her EEG research on the different stages at which girls and women experience strong hormonal f…
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Geert-Jan WillFaculty of Social and Behavioural Sciences
g.j.will@fsw.leidenuniv.nl | 071 5272727
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RESOLVED: Restoration of login functionality on multiple services
The functionality to log in to multiple services has been fully restored after a brief interruption.
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Genetic risk & atypical development: 22q11 Syndrome
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Organisation
The programme group Forensic Family and Youth Care Studies is one of the six programme groups within the department of Child and Education Studies at Leiden University.
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Michelle AchterbergFaculty of Social and Behavioural Sciences
m.achterberg@fsw.leidenuniv.nl | 071 5272727
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stratum corneum lipid chain length relates to an impaired skin barrier function in patients with atopic dermatitis
Source: British Journal of Dermatology, Volume 170, Number 6, pp. E18-E19 (2014) ISBN:0007-0963
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New ecological maps show a wider range of functional diversity
Together with a large international team of scientists, researchers Peter van Bodegom and Nadia Soudzilovskaia of the Leiden Institute of Environmental Sciences (CML) have created maps of variability in plant trait distribution across the globe. The new maps have been published in Proceedings of the…
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Young thinkers pit their brains on the circular economy
How can we speed up the transition from large cities to a circular metropolis? This is the question that Leiden students and former students Elsemieke, Fabian and Eveline are getting their teeth into. They and seventeen other young academics are taking part in the National ThinkTank and they have four…
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Nanoparticles: shapeshifters that pass along the food chain and end up in the brain
Nanomaterials can pass much further along the food chain than was previously thought. The particles can change shape and size in each organism, enabling them to pass on to the next one in the chain. Researchers from the Institute of Environmental Sciences discovered this accidentally when using a novel…
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Zeta-values of arithmetic schemes at negative integers and Weil-étale cohomology
This work is dedicated to interpreting in cohomological terms the special values of zeta functions of arithmetic schemes.
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Interstellar Catalysts and the PAH universe
Organic molecules in interstellar space are important as they influence the structure of galaxies and star formations. Studying catalytic processes in space allows us to understand how molecular species are formed and chemically evolved in the interstellar medium and solar system objects.
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Global distribution patterns of mycorrhizal associations
Mycorrhizas are symbiotic associations between soil fungi and most plant species.
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Application of zebrafish and murine models in lipoprotein metabolism and atherosclerosis research
Cardiovascular diseases are still a major concern for the global health.
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Advances in computational methods for Quantum Field Theory calculations
In this work we describe three methods to improve the performance of Quantum Field Theory calculations.