178 search results for “cognitieve impairment” in the Public website
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Type design for visually impaired children
This doctoral research project in design seeks to shed a light on legibility in the context of visually impaired beginning readers.
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acquisition of verbal morphology in cochlear-implanted and specific language impaired children
This dissertation aims at enhancing our knowledge of whether a CI provides sufficient access to auditory speech input to acquire verbal morphology by comparing outcomes of CI children to those of their normal hearing peers and to those of children with specific language impaired (SLI).
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Impaired barrier of inflammatory skin diseases
Focus in skin research
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empathic mind in children and adolescents with Specific Language Impairments (SLI)
The ‘empathic mind’ in children with Specific Language Impairments (SLI); what can children with SLI understand of other people’s minds and emotions?
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unravelling host-gut microbiota changes in different stages of cognitive impairment
The investigation into the bidirectional communication between the gut and its host is a rapidly growing area of research, attracting considerable attention for its potential to provide crucial insights into health and disease.
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in the hippocampus is sufficient to trigger CREB phosphorylation and impair memory
Source: Mol Psychiatry (2015)
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Development of human skin equivalents to unravel the impaired skin barrier in atopic dermatitis skin
Promotor: J.A. Bouwstra Co-promotor: A. El Ghalbzouri
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Investigations on the role of impaired lysosomes of macrophages in disease
The research described in this thesis combines the latest insights in lysosomal function with lysosome centred cell signalling.
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David BezpalecFaculty of Social and Behavioural Sciences
d.b.bezpalec@fsw.leidenuniv.nl | 071 5272727
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Jennifer BeckerFaculty of Social and Behavioural Sciences
j.m.becker@fsw.leidenuniv.nl | 071 5272727
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Reduced stratum corneum lipid chain length relates to an impaired skin barrier function in patients with atopic dermatitis
Source: British Journal of Dermatology, Volume 170, Number 6, pp. E18-E19 (2014) ISBN:0007-0963
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Zijian LiSocial & Behavioural Sciences
z.li.20@fsw.leidenuniv.nl | 071 5272727
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Shannon YuenFaculty of Social and Behavioural Sciences
s.yuen@fsw.leidenuniv.nl | 071 5272727
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Hanneke HulstFaculty of Social and Behavioural Sciences
h.e.hulst@fsw.leidenuniv.nl | 071 5272727
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PhD Thesis: Development of human skin equivalents to unravel the impaired skin barrier in atopic dermatitis skin
Recently, the PhD thesis of Lolu Danso Eweje appeared entitled ’Development of human skin equivalents to unravel the impaired skin barrier in atopic dermatitis skin’.
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Between smiles and grimaces
In her book Between Smiles and Grimaces, Mariska Kret shows us what differences there are between humans and animals, and more importantly, what similarities.
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The Acquisition of Personal Pronouns in Cochlear-Implanted Children
This dissertation examines whether a cochlear implant provides congenitally deaf born children with sufficient auditory input to acquire low salient and syntactically and semantically complex functional items such as personal pronouns compared to their hearing peers.
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Music production and its role in coalition signaling during foraging contexts in a hunter-gatherer society
For the first time, a group of international and interdisciplinary researchers led by Karline Janmaat and her former MSc Student Chirag Chittar, have tested the several hypotheses on music simultaneously in a modern foraging society during their daily search for tubers – their staple food. They found…
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Neuropsychology of navigation
What is the neurocognitive structure of human navigation ability? What different types of navigation impairment can be distinguished? How can navigation impairment best be diagnosed and treated? How can tools like serious gaming and virtual reality be used to diagnose and treat navigation impairment…
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Human epidermal lipid biosynthesis in health and disease
How are the epidermal lipid pathways involved in health and disease.
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People
The research team
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Social and emotional competence in children and adolescents who are Deaf or Hard of Hearing (DHH)
How does having limited access to the social world affect Deaf or Hard of Hearing (DHH) children’s emotional development? And in turn, how do impairments in emotional functioning affect social development and the development of psychopathology?
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Focus on Emotions research group
We examine the effect of social learning on emotional competence in children and adolescents with a typical or atypical development.
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Products and downloads
Here you can find products and research tools developed by the Navigation Lab Leiden
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Noonan and LEOPARD syndrome in zebrafish: molecular mechanisms and cardiac development
Promotor: Prof.dr. J. den Hertog
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Optimisation of first clinical studies in special populations: towards semi-physiological pharmacokinetic models
Promotor: M. Danhof, Co-promotores: J. Freijer, A. Yassen
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Student support services
Perhaps you have questions about your studies or could use some extra help? Or maybe you’d like some support of a more personal nature? At Leiden University we have people and departments who are glad to help out in any and all of these areas.
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Cell-autonomous and host-dependent CXCR4 signaling in cancer metastasis: insights from a zebrafish xenograft model
Promotor: A.H. Meijer, Co-promotor: B.E. Snaar-Jagalska
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PAIR: The Journal
PAIR, Psychoeducational Assessment, Intervention and Rehabilitation, is the online Open Access journal associated with ENPAIR.
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Fusing Electrical Stimulation and Wearable Robots with Humans to Restore and Enhance Mobility (Book Chapter)
Eduard Fosch-Villaronga, Associate Professor at eLaw, contributed to 'Cyber–Physical–Human Systems', a book exploring the latest developments in interactions between cyber–physical systems and humans.
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OortNiels Bohrweg 2, Leiden
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Measuring emotional competence across cultures in children and adolescents from 1 to 15 years old
Development and validation of instruments that can measure different aspects of emotional competence in children with normal and atypical development, and in different cultures
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Topic: Self-management in chronic diseases
Having a chronic somatic condition can result in a variety of impairments in patients’ daily lives, including not only physical complaints such as pain, itch, and fatigue, but also problems of negative mood and impairments in social relationships. Next to disease characteristics, individual difference…
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Cognitive Emotion Regulation Questionnaire (CERQ)
CERQ is a questionnaire measuring cognitive coping strategies developed by Dr. Nadia Garnefski and Dr. Vivian Kraaij.
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Contact
Contact Institute of Environmental Sciences (CML)
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Monounsaturated fatty acids reduce the barrier of stratum corneum lipid membranes by enhancing the formation of a hexagonal lateral packing
The effectiveness of the skin barrier underlies the outer layer of the skin: the stratum corneum (SC). However, in several skin diseases this barrier is impaired. In two inflammatory skin diseases, atopic eczema and Netherton syndrome, an increased level of monounsaturated fatty acids (MUFAs) has been…
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Translational Neuroscience
Within the LUMC medical research profile Translational Neuroscience innovative multidisciplinary research is performed on a number of severe disorders of the brain, nerves and muscles.
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Rapid and profound rewiring of brain lipid signaling networks by acute diacylglycerol lipase inhibition
Diacylglycerol lipases (DAGLα and DAGLβ) convert diacylglycerol to the endocannabinoid 2-arachidonoylglycerol. Our understanding of DAGL function has been hindered by a lack of chemical probes that can perturb these enzymes in vivo.
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The important role of stratum corneum lipids for the cutaneous barrier function
The skin protects the body from unwanted influences from the environment as well as excessive water loss. The barrier function of the skin is located in the stratum corneum (SC).
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Lecture HallEinsteinweg 57, Leiden
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Research lines
Current research at the Skin Barrier and Vaccination group.
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Controlling anxiety in late life (CALL)
Primary Objective: The primary aim of the proposed RCT is to evaluate whether LF-TLP in blended form as an indicated prevention for anxiety complaints is more (cost-) effective than TAU according to the NHG guideline Anxiety. We hypothesize that in comparison to TAU, LF-TLP will result in a significantly…
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Development and evaluation of evidence based self-help and online programs for people with a somatic stressor and depressive symptoms
What is the effectiveness of (booklet or online) self-help programmes for people with somatic stressors and depressive symptoms? What works best for whom? How to improve motivation and adherence?
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Topic: Psychosocial consequenses of ICU treatment
In case of serious illness, treatment in the Intensive Care Unit (IC) may be necessary. Intensive care treatments has improved over the years and more and more seriously ill patients are surviving admission to the ICU. This favorable development however has a downside since long-term consequences of…
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Pre- and perinatal risk factors
Effects of maternal smoking, premature birth, intra-uterine growth retardation and asphyxia on child development.
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Neurofibromatosis Type I
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How to get there
Route descriptions to CML by public transport or car
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The importance of free fatty acid chain length for the skin barrier function in atopic eczema patients
An important feature of atopic eczema (AE) is a decreased skin barrier function. The stratum corneum (SC) lipids - comprised of ceramides (CERs), free fatty acids (FFAs) and cholesterol - fulfill a predominant role in the skin barrier function.
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Nanomaterial safety for microbially-colonized hosts: Microbiota-mediated physisorption interactions and particle-specific toxicity
The external tissues of plants and animals are colonized by microbial communities termed microbiota. When organisms are exposed to environmental pollutants, these substances will therefore encounter microbiota at the exposure interface.
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Calcium-dependent regulation of auxin transport in plant development
The plant hormone auxin regulates plant growth and development through polar cell-to-cell transport-generated maxima and minima. PIN FORMED (PIN) auxin efflux carriers determine the direction of this auxin flow through their asymmetric placement on the plasma membrane (PM).