The doctor suggests opting for a treatment that is better for the environment. How do patients react to this? Doctors and psychologists together discovered that this has little impact on patient confidence in the doctor.

A cancer pill, preferably without severe side effects, is something we’d all welcome. Is it a matter of time before such a pill is a reality? We put this question to three Leiden researchers and asked how they themselves are contributing to new cancer treatments.

Working in a laboratory is different from working in an office. Some of the rules that apply when working in or around a laboratory are given below.

Researchers from the Leiden University Medical Center (LUMC) have successfully used stem cell gene therapy to treat a baby with the severe congenital immune disorder SCID. An important milestone: it is the first time stem cell gene therapy of Dutch origin has been administered to a patient, and also…

If doctors could better estimate a patient's chances of survival, this would help in choosing a specific treatment. It would be particularly beneficial for the rare and malignant Ewing sarcoma, which mainly affects children and adolescents. Mathematics professor Marta Fiocco has been awarded a substantial…

As technology transforms healthcare and services come under mounting pressure, one question remains the same: Will the advice or treatment offered help patients lead the lives they want to live? In her inaugural lecture, Professor Maxime Kummeling stresses the importance of quality.

Jasper Knoester startte op 1 januari als onze nieuwe decaan. Hoe gaat het met hem, wat doet hij precies en hoe ziet zijn dag eruit? In elke nieuwsbrief geeft Jasper een inkijkje in zijn leven als decaan.

In the Netherlands, 1.55 million people suffer from cardiovascular diseases. Yet, acute cardiovascular events, such as a heart attack or stroke, often occur unexpectedly. That is because many people do not know they are at risk for such an event. Immunological researcher Amanda Foks and her colleagues…

Could we stop cancer cells by cutting off their energy supply? That’s what Dione Blok, a bachelor’s student in Bio-Pharmaceutical Sciences, aimed to find out during her thesis research. She investigated a compound that affects the tumour cells’ energy metabolism. ‘Hopefully, these insights will provide…

The more data from cancer research we pool, the better we can search for new treatments. But how can we keep patient data safe when sharing it? Leiden researchers will tackle this challenge in a major European project.

One in two people will be diagnosed with cancer. World Cancer Day on 4 February raises awareness of the impact of this devastating disease. Leiden University is conducting various studies aimed at preventing and controlling cancer. Below are just a few examples.

Nerve pain is one of the most common side effects of chemotherapy. It is therefore one of the biggest reasons for cancer patients to stop treatment early. Darcy Reynolds worked on new drug candidates against this pain during her bachelor's thesis. She developed a new series of molecules that increase…

Statistician Anja Rüten-Budde has won the C.J. Kok Jury Award 2020. Her PhD thesis resulted in an app which helps patients with soft tissue sarcoma and their doctors to make well-considered choices about the treatment. ‘Her work is interdisciplinary and directly relevant for society,’ the jury state…

As part of the ZonMW Antibiotics resistance funding program, the LACDR cluster Systems Pharmacology was awarded €455.255 for a research project to develop novel clinical biomarkers for bacterial infections.

Five consortia within the Perspectief programme that include Leiden researchers have received funding to start their research projects. These projects focus on (further) developing technological innovations, with societal and economic impact at their core.

To inhibit proteins that contribute to the growth of aggressive cancer cells, that’s the plan of Professor Bob van de Water and his team. They will receive over 700,000 euros from the KWF Dutch Cancer Society for their research. Researcher Maaike Vreeswijk and pathologist Danielle Cohen are affiliated…

A Dutch consortium has received €6.7 million to accelerate the development of nanomedicines together with patients. Researchers from Leiden University play a key role in the project.

One discovered that arteriosclerosis resembles an autoimmune disease, while the other developed a system to aid in the search for new medications. For these achievements, Marie Depuydt and Jurren de Groot were awarded the Krijn Rietveld Memorial Innovation Award on the evening of Tuesday 4 June.

Organs and tissues grown in the lab may in the future be able to cure people with organ failures. Micha Drukker, professor of Stem Cells, Developmental Biology and Technology for Innovative Drug Research, is convinced that the use of stem cells will make this possible. He will deliver his inaugural…

Is it a coincidence that three chemists from the same department have each independently received a ZonMw grant? 'No,' the researchers agree in unison. 'The role of chemistry in medical biology is becoming increasingly important, and we’ve worked hard to make this happen.'

The Dutch Research Council (NWO) has awarded Vidi grants to Leiden researchers.

Only one in five young people with emotional health problems such as an anxiety disorder receives appropriate professional help. GPs often fail to properly recognise the signals in children and young people, according to psychologist Semiha Aydin. How can we improve this? PhD defence 23 February.

Mathematics can help predict thrombosis. Mathematician Mark Alber has developed models that even aid in suggesting treatments. In the Kloosterman lecture on 27 June, he will explain how this works.

When a bacterium becomes more resistant to one antibiotic, it sometimes becomes more sensitive to another. To better understand this interaction, researchers from the Leiden Institute of Biology (IBL) and the Leiden Academic Center for Drug Research (LACDR) under supervision of Daniel Rozen and Coen…

The promising early results of an international study have shown that insulin-producing cells grown from stem cells can cure the disease. The new Cure One LUMC research centre aims to accelerate this breakthrough.

The Leiden University Medical Center (LUMC), the Danstem Institute from the University of Copenhagen and the Murdoch Children’s Research Institute in Melbourne have received 300m euros from the Novo Nordisk foundation. The aim of this new international consortium is to bring stem-cell based therapies…

Biophysicist Alireza Mashaghi and his collaborators are taking up the fight against muscular dystrophy: genetic disorders that cause muscle weakness. They want to inhibit the clumping of proteins that results in toxic aggregates. For this, the team receives 550,000 euros from Health Holland. The team…

Biological chemist Nathaniel Martin and his team received an NWO grant to examine how blocking a specific enzyme in our body, NNMT, could be helpful in the treatment of some cancers. Trials with mice have been promising, and together with the Netherlands Cancer Institute, Martin wants to take the next…

Four Leiden researchers have been awarded Proof of Concept grants by the ERC. These grants, each worth 150,000 euros, help researchers translate the findings of previous ERC projects into innovative practical applications.

Funded by a ZonMw grant, the LUMC and the Health Campus The Hague will be working with headache patients on research into the use of an electronic headache diary. This resource can help patients gain a better understanding of their migraine attacks and, together with the physician, produce the best…

Bringing your drug candidates to patients is what many academic chemists dream about, but the road to this goal is long and bumpy. Now, Leiden small molecule nizubaglustat is ready for phase 3 clinical trials. This is thanks to a €132 million funding secured by the biotech spin-out Azafaros.

Bacteria whirl around in the mouths of most people, forming dental plaques and sometimes causing nasty gum infections. Treponema denticola might be a dangerous pathogen, but not much is known about this bacterium. It was up to Ariane Briegel and her research group to change that.

Researchers have discovered the most distant Milky-Way-like galaxy yet observed. Dubbed REBELS-25, this disc galaxy seems as orderly as present-day galaxies, but we see it as it was when the Universe was only 700 million years old. This is surprising since, according to our current understanding of…

Astronomers led by Leiden PhD candidate Richelle van Capelleveen have, for the first time, discovered an exoplanet that has carved a bright gap in the protoplanetary disc around its star. This rare observation provides new insights into how young planets shape their surroundings.

A patent for what may be a potent, new antibiotic. And: a clear overview of promising approaches to overcome a crucial resistance tactic employed by bacteria. In the span of one week, two researchers from Leiden are receiving their PhDs, each of them on an important step in the battle against bacteria…

An impressive 22 research projects by Leiden researchers have been awarded Veni funding from the Dutch Research Council (NWO).

For the first time, astronomers have observed in three dimensions that gas from spiral galaxies is blown upwards and downwards at high speed, far out of the galaxy. They thereby confirm the theory of galaxy evolution: that star-forming galaxies create intergalactic gas flows by discharging gas along…

Astronomers led by Simon Portegies Zwart used simulations to reconstruct how three stars were ejected from the star cluster R136, 60,000 years ago. The analysis reveals that five stars were involved in the event in the Tarantula Nebula.

The shock wave triggered by one of the five galaxies making up the iconic Stephan’s Quintet appears to be less disruptive than previously thought, with the shock likely being cushioned by dust particles in the surrounding gas. This is according to the analysis of the first scientific observations of…

Researchers from Leiden University Medical Center (LUMC) and the Leiden-based biotech company Ncardia have joined forces to develop a new platform that enables the automated production of 3D cardiac microtissues. This platform will allow large numbers of drugs to be tested quickly

Antibiotic resistance is a common problem among patients. The European Project TIPAT trains pharmacologists, microbiologists and immunologists of six universities in interdisciplinary thinking. The ultimate goal is to develop better treatment guidelines to combat resistance. Coen van Hasselt of the…

Skåne University Hospital, Lund University and Leiden University Medical Center will work together to expand their research, teaching and development relating to Advanced Therapy Medicinal Products. That is the essence of a Memorandum of Understanding signed at SciLifeLab near Stockholm on Wednesday…

Are you a PhD candidate, and is there something you’d prefer to discuss with someone other than your thesis director or supervisor? The confidential counsellor for PhD candidates is here to help. You can speak to him/her in confidence and receive advice. If you experience symptoms of physical or mental…

Our confidential counsellors can provide confidential advice on a range of issues, including bullying, intimidation, sexual harassment, aggression and discrimination. You can also approach them with concerns about your manager or potential breaches of academic integrity.

Are you an international researcher working for Leiden University? Please note that you probably are legally obliged to take out health insurance. Here you will find if you need a public or a private health insurance, and how to apply for it.

For the academic year 2025-2026, nine (teams of) teachers will receive a Grassroots or Grass shoots grant. Here you can read about their projects.