Plant exudates appeared long time ago in the history line of life in the early Devonian. They are typical saps produced by specialized cells.

Dissolving microneedles are a subgroup of microneedle types that completely dissolve within the skin. During this dissolving process the vaccine, stored in the needle matrix, is released into the skin.

Prematurely born neonates require, amongst others, pharmaceutical therapy. Dosing guidelines for these therapies are often based on data from term born neonates or older infants, while these are not necessarily similar to prematurely born neonates.

Immunotherapies for cancer are an emerging class of therapeutic strategies which aim to treat cancer via augmentation of the immune system.

Promotors: Prof.dr. P.G.L. Klinkhamer, Prof.dr. P.M. Brakefield

New and reemerging infectious diseases call for innovative and efficient control strategies of which fast vaccine design and development represent an important element.

Bacteriophages, or phages for short, are the most abundant biological entity in nature. They shape bacterial communities and are a major driving force in bacterial evolution.

Antibiotic-resistant bacteria pose a major health threat. Addressing this challenge requires among others the development of new antibacterial compounds. The research described in this thesis focuses on discovering novel antibiotics from soil bacteria, specifically Streptomyces and Paenibacillus.Despite…

Seasonal influenza vaccines provide protection against matching influenza A virus (IAV) strains mainly through the induction of neutralizing serum IgG antibodies. However, these antibodies fail to confer a protective effect against mismatched IAV. This lack of efficacy against heterologous influenza…

β-Lactamases are enzymes that can break down β-lactam substrates, such as antibiotics, preventing the use of these antibiotics for the treatment of various infectious diseases. However, some compounds, β-lactamase inhibitors, can block these enzymes allowing for possible treatments using a combination…

Addressing the core novel objective of scalably assessing the impact of possible interventions through counterfactual prediction based on spatio-temporal data.

Leiden University seeks to bring knowledge, academic top talents, and resources from Leiden and Latin America and the Caribbean together in mutually beneficial joint research projects that are content-driven, based on existing excellent research. Connecting research and researchers.

Timely, adequate and optimal treatment of infectious diseases is essential for the survival of patients with bacterial infections (Surviving Sepsis campaign).

We perform multidisciplinary research at molecular, cellular, and organismal levels of animal biology to increase fundamental understanding of health and disease.

This dissertation presents the synthesis and evaluation of antibody recognition for various capsular polysaccharide (CP) fragments of Staphylococcus aureus (S. aureus).

Overkleeft

Can the venom of snakes, scorpions and other animals be sources of new antibiotics?

The Children’s Rights Monitor provides a thematic overview of the implementation of the UN Convention on the Rights of the Child in the Netherlands.

The first index to measure product safety, sustainability, and circularity, operationalising the EU’s (SSbD) framework.

The “harpe organisée”, 1720-1840: Rediscovering the lost pedal techniques on harps with a single-action pedal mechanism, is the title of Maria Christina Cleary's PhD thesis. This is the first monographic study on harp pedal techniques, tracing the historical way to pedal on the early pedal harps with…

From Crisis to Critique

De lichtheid van literatuur: Engagement in de multiculturele samenleving (The Lightness of Literature: Engagement in the Multicultural Society) is a plea for the social relevance of literature. The book delves into an age-old debate about literature and social engagement, which has recently been reinvigorated…

This study interrogates contemporary and historical uses of barbarism, arguing that barbarism also has a disruptive, insurgent potential.

The Behavioral Public Administration Lab (BPA Lab) conducts behavioral science to generate, share, and apply insights about human behavior to improve governance, policy, and management in the public sector.

This anthology contributes to a historically grounded understanding of the complex relationship between Christian missions and the roots of humanitarianism and its contemporary uses in a Middle Eastern context.

The Children’s Rights Monitor provides a thematic overview of the implementation of the UN Convention on the Rights of the Child in the Netherlands.

The central inquiry of this thesis revolves around how ontology can adequately accommodate the existence of necessary physical relations. Initially, the thesis demonstrates the imperative acknowledgment of necessary physical relations by showcasing the failure of Neo-Humean theories.

Reconstructing interactions between communities in and out of Cyprus in the early third millenium BC

A main goal of MSBB research is to address the major bottle-necks in combatting viral diseases: the lack of experimental models that are representative of human pathology and are cost effective and versatile. Viral diseases such as those that cause viral hemorrhagic syndromes or severe acute respiratory…

In a new study, we found that when we are exposed to potential harm to the other person, it improves our automatic attentional processes to avoid harm to that person.

Studying the underlying principles of the nature of language.

This collection considers such issues as the cognitive, linguistic and emotional benefits of speaking two languages, the perceptions, attitudes and issues relating to identity in minority language areas, and the number of grammatical aspects amongst those who speak these minority languages.

How to related figures of savages to conceptions of history?

The HOPES study is one of the largest investigations of this kind to date! By studying existing brain scans and data collected form over 4,000 14-25 year olds, the project team hopes to identify specific changes in the brain that make young people vulnerable to suicidal thoughts and behaviours.

In this article, Yannick Veilleux-Lepage and Tommy van Steen, assistant professors at the Institute of Security and Global Affairs, discuss the degree of consensus within the field of terrorism studies regarding the impact of the COVID-19 pandemic on the activities of violent non-state actors.

Pre-modern long-distance trade was fraught with risks which often created conflicts of interest. The ensuing disputes and the ways the actors involved dealt with them belong to the field of conflict management.

In this article, Maria-Elena Kisyova, Yannick Veilleux-Lepage and Vanessa Newby shed some light on how a small but highly visible group of influencers are actively working to promote a dangerous far-right ideology.

Taal als sleutel tot het begrijpen van de mens.

How do speakers adapt to multilingual contexts?

Do you wish to contact us for further information on the collaboration between Leiden University and Indonesia?

Lecture

On this page you will find an overview of awards and prizes granted to our staff and students in 2024, as well as special appointments at Leiden University and other institutions.

Freezing bacteria super fast to gain a true-to-nature image of the internal and external structure. Ariane Briegel Professor of Ultrastructural Biology came to Leiden specially to carry out this research. Leiden University is one of the few institutes in the world to have the necessary equipment. Inaugural…

The current COVID-19 vaccination campaign involves injecting the vaccine into muscle tissue, but injecting a smaller amount of vaccine in the skin might also provide good protection. The #wakeuptocorona crowdfunding campaign has enabled Anna Roukens (LUMC) to examine the safety and efficacy of vaccination…

PhD defence

PhD defence