This thesis aimed to investigate the impact of exposure dynamics, relative contributions of ENPs(particle) and ENPs(ion), and dosing regimens on the toxicity of ENPs varying in different physico-chemical properties, on the composition and functioning of soil microbial communities.

Promotor: J.A. Bouwstra Co-promotor: A. El Ghalbzouri

Continuous optimization is never easy: the exact solution is always a luxury demand and the theory of it is not always analytical and elegant.

Professor Pieter ter Keurs has spent his entire career studying collecting. Now, he is retiring. ‘I hope the focus on collections will carry on.’

Jens Iverson, Assistant Professor of International Law and a Researcher in the Jus Post Bellum Project, defended his Ph.D. dissertation on 21 September 2017.

Evidence and Care-work in a home visiting program to promote maternal sensitivity and parental reflective functioning in Alexandra township, Johannesburg, South Africa.

Despite considerable progress in the design of multifunctionalized nanoparticles (NPs) that selectively target specific cell types, their systemic application often results in unwanted liver accumulation. The exact mechanisms for this general observation are still unclear.

This thesis studies operator-algebraic aspects of subproduct systems, a generalization of product systems of Hilbert spaces.

The polypept(o)ide hybrid material attracted more and more attention over the past decade by combining the multifunctional characteristics of polypeptides with the shielding characteristics of polypeptoid-pSar possessing similar properties as a shielding material as polvethylene glycol(PEG). Polysarcosine…

Papers written on the occasion of the 30th anniversary of the Institute of Prehistory, Volume I.

This perspective addresses four challenges facing theorists whose aim is to make quantitatively accurate predictions for reactions of molecules on metal surfaces, and suggests ways of meeting these challenges, focusing on dissociative chemisorption reactions of H2, N2, and CH4.

Promotor: H.J.M. de Groot, Co-Promotor: A. Alia

Promotores: Prof.dr. H.J.M. de Groot, Prof.dr. J. Matysik (Universitaet Leipzig)

Practical applications for the reconstruction of the past

To what extent did the street patterns in urban districts influence crime patterns?

Cardiovascular diseases are the primary cause of death in the world with atherosclerosis as primary underlying cause.

In the thesis the dynamics of strategies is studied from two perspectives.In the first part of the thesis strategies are considered to be opinions present in a community.

The rise and fall of the cesspit in an urban context

Promotor: Prof.dr. T.J. Aartsma, Co-promotor: R.N. Frese

Due to its economic prosperity, its policy of (relative) religious tolerance, and its large numbers of migrants, the Dutch Republic has long had a reputation of being the prime example of ‘tolerance’, especially during the seventeenth century. Although the great variety of newcomers in the Dutch Republic…

This year, in a three-part symposium series, we are exploring how interdisciplinary collaboration can be promoted at the university. In the second session in March, the attendees discovered that understanding your rhythm and perspective is essential when embarking on an interdisciplinary project.

This thesis investigates how cell shape and collective behavior influence the dynamics and structure of biological tissues, which are crucial for understanding processes like embryonic development, tissue regeneration, and metastasis.

How did a circle of Soviet artists and writers virtually unknown until perestroika turn into Russia’s most influential contemporary art movement? This book reconstructs the cultural history and canonization of a group of painters and poets known as the Moscow conceptualists, who paradoxically did not…

This study looks at population response to government containment strategies during initial stages of the COVID-19 pandemic in four high-trust Northern European countries–Denmark, Germany, the Netherlands, and Sweden–with special emphasis on expressions of governmental trust.

An interdisciplinary cultural analysis of how the Hindustani double migration informs contemporary processes of identification and problematises the juxtaposition of tradition and modernity.

Leiden-Yale collaboration uncovers a tale of samurai same-sex love in a library manuscript.

The work described in this dissertation contributes to a better mechanistic understanding of nanoparticles in vivo. To achieve that goal, we used the zebrafish as a highly predictive pre-screening model of nanoparticles.

Much attention has been paid to the exchange of objects, ideas, and people in the Caribbean. Networks of interaction connected local communities across pan-regional scales, shaping indigenous socio-political integrations and their responses in colonial situations. This work examines the poorly understood…

This book was published in conjunction with an exhibition at the Pera Museum in Istanbul. It contains seven articles on the global panoramic visual history from the early modern to modern times and Istanbul's place within this history.

Nichiran kankei-shi o yomitoku [Revisiting the History of Dutch-Japanese Relations] is a new, two-volume Japanese publication with a chapter written by Wulan Remmelink. Both volumes offer a new look on the historical relations between Japan and The Netherlands during the Edo period by examining various…

Death in all types of melanomas is generally caused by metastasis. Uveal melanoma (UM) is the most common intraocular melanoma, there are currently no (patient-derived) animal models that faithfully recapitulate metastatic dissemination of UM.

Schistosomiasis is an acute and chronic disease caused by blood dwelling parasitic trematodes of the genus Schistosoma, and it is classified as the second most socioeconomically devastating parasitic disease, second only to malaria.

The Centre for Indigenous America Studies (CIAS) at Leiden University is designed to coordinate and promote the teaching and research of Indigenous languages, literatures, cultures and cultural heritage. Our aim is to contribute to an increased acknowledgement, recognition and understanding of Indigenous…

An investigation into how racial stereotypes were created and used in the European Middle Ages.

Promotor: Prof.dr. M. Danhof

Atherosclerosis is a progressive disease resulting in the formation of an arterial plaque. Despite lipid lowering, recurrent cardiovascular events remain a risk. While atherosclerosis is primarily lipid-driven, the immune system plays a critical role in the pathophysiology.

Adenosine is an endogenous ligand which exerts its action by activating adenosine receptors (ARs), while its circulating levels are controlled via a variety of mechanism and proteins, amongst others the equilibrative nucleoside transporters (ENTs).

This research project adresses the question how local and traditional European forms of parrhesiastic theater— events, actions, and performances staged by characters who courageously speak their minds through scenes of excess and laughter, that take place in public view and incite the spectator’s agency…

Social Aspects of Space in the Configurational Architecture of Frankish Castles in the Holy Land, 1099-1291

Our team is committed to the study of knowledge in its broadest sense, encompassing both ideas and practices in all its historical variety. We look at what people regarded as knowledge, how they created, collected, circulated and used it, also why it mattered to them, and how all this was embedded in…

Lecture, Lunch Research Seminar

The lipids in the uppermost layer of the skin, the stratum corneum (SC), play an important role in the skin barrier function. The three main SC lipid classes are ceramides (CER), cholesterol and free fatty acids.

Regular users of cannabis are less aware of their own mistakes, and they are not good at creative thinking. This is the conclusion drawn by psychologist Mikael Kowal from his research on the effects of cannabis. PhD defence 6 October.

PhD defence

This PhD project develops and applies a GIS procedure to use legacy survey data in settlement pattern analysis. As part of the research by the LERC project (NWO, Leiden University, KNIR), legacy data produced by surveys in central and southern Italy are examined in a comparative framework to investigate…

James Shires has contributed a chapter to the proceedings of the 13th International Conference on Cyber Conflict (CyCon 2021), which gathers 20 articles from the law, technology and strategy domains.