A major new study of ancient DNA has traced the movement of people into southern Britain during the Bronze Age. In the largest such analysis published to date, scientists examined the DNA of nearly 800 ancient individuals. Publication in Nature on December 22, 2021.

From malaria parasites as a vaccine to how top-level bureaucrats reach their decisions: seven researchers from Leiden University have received a Vidi grant from the Dutch Research Council (NWO). This 800,000-euro grant will enable them to develop their own innovative line of research over the next five…

SAILS and CAIRELab, the LUMC’s AI expertise centre, recently held an event that gave healthcare professionals and computer scientists the chance to meet. The meeting proved fertile ground for new collaborations.

Does medicine make patients feel better or worse? We are getting better at predicting this from people’s DNA profiles, says Professor Jesse Swen. ‘It never fails to fascinate me how one DNA base pair can have such a huge effect on treatment with medication and the outcome.’

Leiden researchers have found clues to why a rare pregnancy disorder is mild in some babies but life-threatening in others. Their discovery opens the door to a test that could identify severe cases during pregnancy. Fortunately, a treatment already exists.

The Board of Governors is pleased to announce that Professor Cisca Wijmenga has been appointed by outgoing Minister of Education, Culture and Science Robbert Dijkgraaf as its new member.

There seem to be genes that influence how our brains develop over time. A large international consortium has discovered this with an extensive study. The results of the study were recently published in Nature Neuroscience.

Leiden's iGEM team has won high honours at the Grand Jamboree in Paris. The biology students came second in the Overgraduate category with their project PHAse Out. They also took home awards for Best Biomanufacturing Project, Best Wiki and Best Entrepreneurship as well as a Gold Medal. To top it all…

RARE-NL, a new collaboration between university hospitals, hopes to find treatments for rare diseases. Professor Teun van Gelder is representing the LUMC in the initiative.

Leiden professor of molecular astrophysics and astrochemistry Ewine van Dishoeck was presented with the Niels Bohr International Gold Medal on Friday 7 October. The medal, instigated by the Danish Society of Engineers IDA, was awarded by Queen Margrethe of Denmark at a ceremony at the Carlsberg Academy…

Veel mensen denken dat zware metalen giftig zijn en mens en natuur altijd schade aanbrengen. Dat beeld moet genuanceerd worden, vindt hoogleraar Sylvestre Bonnet.

The guardian of our genome, the protein MutS, scans the DNA for spelling errors and makes sure they are corrected. An essential process for our health. Researchers at Leiden University Medical Centre (LUMC) have discovered precisely how this protein works by making MutS visible with cryo-electron microscopy.…

Prof. Marcel Reinders is a data science specialist at Delft University of technology. Using smart algorithms, he searches for links in complex data. For example, he studies patterns in DNA that lead to aberrant cell behaviour. This knowledge will help detect serious diseases such as Alzheimer's and…

Tuberculosis stands as one of the most lethal infectious diseases worldwide. A significant challenge in combatting tuberculosis lies in the emergence of antibiotic resistance triggered by genetic alterations, commonly known as mutations. These mutations can diminish the responsiveness to antibiotics,…

One used 3D cell models to study colorectal cancer, while the other used machine learning for more efficient blood donation. For these achievements, Marieke Vinkenoog and Simon Christian Hansmann were awarded the Krijn Rietveld Memorial Innovation Award on Tuesday 2 September.

Herman Spaink knows of many substances that may help combat tuberculosis. Lab space to study them safely is very limited in Leiden. A brand-new lab at Universitas Gadjah Mada in Indonesia will soon provide a solution. About time, says Spaink, ‘The disease is on the rise and is becoming less sensitive…

Four green research institutes in Leiden are joining forces to integrate evolution and biodiversity research, at local and at the national level. Pivot in this collaboration is Frederic Lens.

If an echo (or ultrasound) shows that a foetus has a heart or other defect, parents face difficult decisions. Then an idea of their child’s shorter and longer-term future is literally a matter of life and death. Haak will argue in her inaugural lecture that the cohort studies of rare diseases that are…

Rapid developments in DNA techniques allow researchers to find out more and more about human genetics. An international group of scientists has drawn up five ethical guidelines to ensure that this DNA research is better regulated. Leiden archaeologist Marie Soressi – one of the signatories - explains…

A group of biology students are working on a solution to the world’s plastics problem by getting bacteria to make biodegradable plastic.

Several consortia in which Leiden University is involved have been awarded Dutch Research Agenda funding. Leiden is the coordinator of five of these consortia. These five consortia will receive grants worth a total of almost 24 million euros. They relate to interdisciplinary projects that will bring…

Sander van Kasteren (Professor of Molecular Immunology) makes the invisible visible. He will explain more in his inaugural lecture.

Leiden biologists have found a mutation in flour beetles that allows them to speed up their development. The study has been published in Nature Ecology and Evolution.

Researchers from Leiden University Medical Center (LUMC) have discovered how malaria parasites escape the immune system of mosquitoes. The so-called QC enzyme changes proteins on the outside of the malaria parasite such that the immune cells are unable to recognise the parasite. As a result, the parasite…

The Leiden University Medical Center (LUMC), the Danstem Institute from the University of Copenhagen and the Murdoch Children’s Research Institute in Melbourne have received 300m euros from the Novo Nordisk foundation. The aim of this new international consortium is to bring stem-cell based therapies…

Microorganisms that temporarily ‘go to sleep’ play an important role in the evolution and survival of a population. Mathematician Shubhamoy Nandan conducted research on the effect of this characteristic called ‘dormancy’ in a novel mathematical model.

Many children experience trauma and if they are unable to deal with it properly, it can have a huge personal and societal effect. Building resilience in vulnerable children and young people should therefore have the highest priority. This is the message of Anne-Laura van Harmelen, Professor of Brain,…

In a new study published in PLOS One, Leiden archaeologist Anastasia Nikulina, together with an international team from France, Denmark, the United Kingdom and the Netherlands, challenges the long-held belief that early humans had minimal impact on their environment before the rise of farming.

For over a year now, the James Webb Telescope has been sending stunning images that exceed astronomers’ expectations. The photos are fascinating to see, but what exactly are we looking at? Assistant professor Melissa McClure explains.

Uncovering ageing processes in the brain and research on the use of the word ‘that’. Thanks to a Rubicon Grant, two Leiden researchers who were recently awarded their PhDs will be able to conduct research at a research institute abroad.

In a one-hour interview on Dutch radio programme Sleutelstad, Anne-Laura van Harmelen talks about her research into the role friendships in adolescents' well-being, the resilience paradox and the role of social, hormonal and genetic factors in stress-levels and resilience.

We are congratulating Maaike van der Lee, PhD candidate at LUMC-KFT, for winning the national PhD competition 2021 at the FIGON Dutch Medicine Days. During this national competition, 8 researchers from the major university cities in the Netherlands present their work in the field of innovative medicine…

How do you fulfill a chairing position during a team meeting? How do you visualise a dataset for a presentation? How do you write the introduction to a scientific article? All Science students can find the answers to these and many more questions in the 100+ skill modules on the digital Science Skills…

Luc Amkreutz, curator of prehistory at the National Museum of Antiquities in Leiden and professor of Public Archaeology at Leiden University, has a mission: to make the past accessible and relevant to a broad audience. He is the new Eugène Dubois Visiting Professor at the Faculty of Science and Engineering…

Emeritus Professor of Molecular Astrophysics Ewine van Dishoeck has been named a Citation Laureate by Clarivate, a research analytics provider. Clarivate considers her an influential researcher of the calibre to win a Nobel Prize.