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BlaC is the β-lactamase of Mycobacterium tuberculosis. We show that it can recover from inhibition by clavulanic acid and that phosphate helps it do so.

In the last decades, activity-based protein profiling (ABPP) has emerged as a powerful chemical tool that may aid the ever-challenging drug discovery process.

This thesis investigates the relations between metabolism and anatomy through the use of Magnetic Resonance Imaging (MRI).

This thesis investigates the evolution and fate of gaseous exoplanets, which are continuously shaped by stellar activity across both short and long timescales.

By growing in a soil plants change the biotic and abiotic properties of the soil in which they grow.

This thesis describes the use of bioorthogonal proteins in immunological settings. It provides an introduction towards the field of protein modification, which was used throughout the thesis for the expression of proteins containing unnatural amino acids.

The adenosine receptors are proteins that reside in the extracellular membranes of cells. Activation of adenosine receptors plays a role in many physiological and pathological processes, such as immune responses and cancers.

Multicopper oxidase, laccase, can efficiently reduce oxygen to water and are mostly used in the enzymatic biofuel cells.

Sander van Kasteren (Professor of Molecular Immunology) makes the invisible visible. He will explain more in his inaugural lecture.

Bacterial biocatalysis constitutes a sustainable alternative for high-value chemicals production by enabling the utilization of renewable feedstocks.

We present our plans on five work areas: Students, Inclusive Education, Staff, Research, and Accessible and Inclusive Learning and Working Environment. For each work area, we explain which topics are relevant and what policy measures we (plan to) take.

This thesis describes the development of a variety of mannosylated conjugates. Antigen presenting cells bear mannoside recognizing receptors that actively transport antigen into the cell. This thesis exploits this feature for the development of improved vaccines.

Decent work involves opportunities for work that delivers a fair income, care for occupational health and safety, freedom for people to organize and equality of opportunity and treatment for all women and men. The Labour Law department at Leiden University conducts research and provides education on…

This dissertation combines the use of defined microenvironments, high-resolution fluorescence microscopy, and time-resolved analysis, to study intracellular and cellular motility.

Through his project we will unravel the global regulatory networks that control gene expression in Streptomyces bacteria and allow them to properly respond to major changes in the environment; we will then harness this knowledge to activate and identify novel antibiotics

Promotor: A.P.IJzerman Co-promotor: A. Bender

How can we understand the material instability of photographic (mixed media) artworks (1960s - present) from an integrated approach of Art History, Conservation Science and Chemistry in order to preserve these works for the future?

The Young Academy Leiden and its workgroups have launched different initiatives in the interest of early-career scholars. To find upcoming events, check out our (social) media channels. Below you can see a selection of the initiatives YAL's workgroups have launched.

This study aims to answer two main research questions: (1) What are the main predictors of work ability in employees with migraine? (2) Can we optimise work ability in employees with migraine using a web-based intervention focused on these relevant predictors?

If you’re experiencing too much work pressure, talk about it to your colleagues and your manager. This is the only way we can jointly work towards a solution. How do you raise the issue of work pressure? And what can you do to prevent work pressure from getting out of hand?

The Grotius Centre Working Paper Series is an occasional series through which researchers in the Grotius Centre can publish the unedited versions of manuscripts that have been accepted for publication by journals and books.

The document below contains the faculty D&I work plan drawn up for Leiden Law School. This work plan is linked to the University work plan of the D&I Expertise Office.

Many students want to find themselves a job during their studies, to help cover their expenses for example, or they might want to stay and work in the Netherlands after graduating. While there are certainly possibilities in both these areas, you’ll need to bear in mind that there are also restrictio…

The purpose of eLaw's Working Groups is to stimulate a productive working environment for cooperation within the Center for Law and Digital Technologies at Leiden University.

You've earned your degree and you’re ready to start your career. But where do you end up?

Make sure you have a suitable place to work or study.

The research connected to this topic is related to Work and health.

Want to work at a top university, with excellent career opportunities? Discover the opportunities at Leiden University.

We strive for FGGA staff to feel sufficiently challenged and recognized with an assigned workload that is realistic within their working hours. Besides that, staff should be transparently and correctly informed about their personal career perspectives and growth opportunities within the faculty / un…

The close interaction between organic chemi stry and biology goes back to the late 18th century, when the modern natural sciences began to take shape. After synthetic organic chemistry arose as a discipline, organic chemists almost immediately began to pursue the synthesis of naturally occurring compounds,…

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Business, international organisations and government – you’ll find them all in The Hague. It’s a place where you can exert influence, expand your network, and enter into unique partnerships.

As a contribution to the changing legislation and evolving societal attitudes concerning environmental issues, this project aims to enhance and manipulate the plants’ own natural defense mechanisms against western flower thrips (WFT).

The human body consists of hundreds, perhaps thousands of different types of cells, each with different morphologies and functions, despite having the same genome.

Leiden University's interdisciplinary research programme SAILS funds young interdisciplinary scientists working at the intersection of AI and other fields. How do these researchers experience the work?

The chemical industry must continue to innovate for a more sustainable, healthier society. The reseachers from the Leiden Institute of Chemistry (LIC) contribute by applying their knowledge to themes such as sustainability, energy and health.

This thesis focuses on developing wafer-scale two-dimensional (2D) materials by combining synthesis, transfer, characterization, and device integration of graphene, hexagonal boron nitride (h-BN), and BN-doped amorphous carbon.

Our faculties present themselves as employer.

There are strict conditions relating to work for third parties.

Develop your skills, create campaigns and activities, and turn ideas into reality. Through Una Europa, you can gain work experience together with an international community.

Inaugural lecture