An all-optical transistor, a molecule-sized sensor and a new kind of single-photon source for quantum communication. All dreamed applications of fundamental physics that are one step closer thanks to Robert Smit. On 12 June, he defended his PhD thesis with distinction.

Why does a medicine work well for one person, but cause side effects in another? Research by Laura de Jong shows that it’s not just our DNA that matters – other medicines and illnesses can also affect how our bodies respond.

An atomic vandal has finally been caught! Scientists from Leiden University and the Department of Energy’s SLAC National Laboratory have uncovered the mysterious cause behind the rapid corrosion of platinum electrodes. This breakthrough paves the way for more affordable green hydrogen production and…

Fascinated by science since high school, Alireza Mashaghi Tabari is driven to explore new ways of thinking in medicine. With a strong academic network, he educates students and gives public lectures. For his research at LACDR, he won the C.J. Kok Public Award 2018, making him the Faculty of Science's…

Nine talented Leiden researchers have been awarded a Vidi subsidy by the Netherlands Organisation for Scientific Research (NWO). Vidis are intended for researchers with several years of research experience who want to set up or expand their own line of research.

Paleobotanist Menno Booi discovered that 250 previously described fossil tree species are objectively not distinguishable; they belong to only one single species.

What dose of medicine do you give a child? That depends to a large extent on how quickly their kidneys remove the drug from the blood. For ethical reasons it is impossible to measure this directly in little patients. PhD candidate Sinziana Cristea combined different types of modelling and lots of data…

Autism, Alzheimer’s, and bipolar disorder: can the development of these mental health conditions be influenced by the ketogenic diet? Increasingly, research suggests it might. 'For those it helps, it can be life-changing,' says neuroscientist Eline Dekeyster.

The team of Alireza Mashaghi at the Leiden Academic Centre for Drug Research has found a way to determine and classify the shape of proteins. Their new theory defines the topology of proteins as a simple and precise barcode that allows the identification of all types of folds. ‘This barcode enables…

Industrial ecologists Stefano Cucurachi and Flora Siebler are part of the new consortium PROGENY, which received 3.6 million euros from the European Commission. PROGENY is an exciting project that will study the possibilities of soap films for innovations, such as ultra-thin screens.

By delivering his inaugural lecture titled ‘Where Science Meets Business,’ Simcha Jong accepted his appointment as Leiden’s first Professor of Science Based Business. In his lecture in the Large Auditorium of the Academy Building, Simcha argued that broad universities with a focus on fundamental research,…

Young researchers met this month for the fifth Science Communication Summer School. ‘This is the first time some participants get to meet other researchers who also enjoy science communication. It’s great to see’, says Julia Cramer, one of the coordinators.

‘Children’s rights are somewhat of a poor relation’, says Professor of Law and Health Mirjam Sombroek-van Doorm. In her inaugural lecture, she will emphasise how more attention needs to be paid to children’s rights in current thinking on law and health.

To facilitate the search for new antibiotics. That is the aim of Gilles van Wezel, professor molecular biotechnology at the Institute of Biology Leiden (IBL). He wants to do this by looking at similarities in the DNA of antibiotic-producing bacteria. Van Wezel has been awarded an ERC Advanced grant…

Two bacterial species team up inside the plant root system to rescue their host from fungal infection. This was discovered by a team of microbiologists and bioinformaticians from the Netherlands Institute of Ecology, Wageningen University, and the Institute of Biology Leiden. They also identified the…

Cancer research generates massive amounts of data, but traditional tools often fail to fully harness their potential. How can we unlock this data to provide better treatments for cancer patients? PhD candidate Marina Gorostiola González explored this by using advanced data analysis techniques to guide…

Martina Huber, Jacqueline Labra Munoz research Alzheimer's disease. They study ferritine, iron storage in the brain. An inbalance of iron could play a role in this form of dementia.

On 29 October, seven innovative lecturers from different faculties will join the existing ten fellows of the Leiden Teachers' Academy. The current fellows have been engaged for the past year in implementing their innovation projects. How are these progressing?

Everything around us is in motion. Students, the University, technology, society, the labour market and the world. These developments provide an impetus to experiment with new forms of education. This article samples a small selection of the many dozens of innovative educational projects. What is striking…

Strengthening a cancer patient's own immune system so that the body itself can better destroy cancer cells. This is at the heart of immunotherapy, the most promising progress in cancer treatment in recent years. In order to drive this development further, the Netherlands Cancer Institute-Antoni van…

A new technique using fluorescent imaging to track the actions of enzymes might aid drug design for new anti-cancer, inflammation and kidney disease treatments. Researchers at the University of York and Leiden University have published these findings in Nature Chemical Biology.

Hundreds of thousands of Dutch people suffer from pain caused by knee osteoarthritis and the number is rising fast. Prof. Jaap Harlaar specialises in clinical biomechanics. His research is helping improve osteoarthritis treatment. Harlaar has been appointed Medical Delta Professor and now holds posts…

For the International Day of Women and Girls in Science, women students and researchers from physics talk about what inspires them about their work. From quantum to cosmology and biophysics, their curiosity about how nature works is what connects these women. What do these 5 scientists want to share…

This project on the role of FoxPs in vocal perception and production learning is part of nine PhD-positions funded by the NWO Gravitation Programme which was granted to the Dutch Research Consortium 'Language in Interaction'

The question of land property titles is a common source of conflict between indigenous communities and federal authorities all over the Americas. A new Panamanian law have led indigenous communities to reach out to archaeologist Dr Natalia Donner. A grant from the Centre for Indigenous American Studies…

A microscope with incredible sharpness that leaves samples unharmed – Guido Stam helped develop one. During his PhD research, he combined light and electrons to study biological samples. ‘We can now measure things that simply weren’t possible before.’

A soap film with chemically distinct sides: it's the latest breakthrough in the research led by chemist Sylvestre Bonnet. This unique soap film, along with an innovative device capable of continuously producing new soap films, forms a crucial piece in the puzzle for the development of artificial pho…

How do opinions form and change in large groups of people? That's not just a sociological question, it's a mathematical one. PhD candidate Federico Capannoli studied opinion dynamics. He defended his thesis on November 19.

How do you ensure that a drug has an effect on the right protein – and nothing else? Chemist Anthe Janssen explored various methods for determining the selectivity of potential medicines. He also looked at the substance BIA 10-2474, after a man died in a French clinical trial in 2016. PhD defence on…

The first of April was the official start of Phase II of the collaborative “PCAD4Cod”-project on the effect of sound on fish populations. Hans Slabbekoorn, associate professor at the IBL, is the principal investigator and collaborates with three PhD-students, Dr. Erwin Winter, (Wageningen Marine Research),…

Whether a microbe is beneficial or harmful to a plant can now be predicted with high accuracy thanks to bacLIFE. This bioinformatic tool with an intuitive interface makes it much easier to unlock the secrets of bacterial genomes. A group of Leiden biologists presented it in Nature Communications.

Lotje Zuur sometimes has to perform disfiguring operations. As a head and neck surgeon, she removes parts of the mouth, throat or face of people with cancer. Now a promising treatment may make such operations unnecessary. What would this mean for patients? This is what her inaugural speech on 19 September…

By measuring proteins in tears, ophthalmologists can more easily diagnose dry eyes (Dry Eye Disease). Peter Raus, a Belgian ophthalmologist and PhD student at the Institute of Biology Leiden, developed a new method for protein determination in tear fluid. The technique is also promising for the early…

Newts of which half of the offspring die before birth. Evolutionary biologist Ben Wielstra is investigating how this can exist in nature. In his research he collaborates with Naturalis Biodiversity Center.

Hans Slabbekoorn is specialised in animal sounds. On 1 July, he was appointed professor of Acoustic ecology and behaviour. A great honour, according to the new professor. ‘This job never gets boring, whether I am investigating the urban jungle or marine noise.’

There are more molecules that could conceivably be candidate drugs than there are stars in the universe. How can we ever efficiently identify those molecules? Professor of AI and Medicinal Chemistry, Gerard van Westen: ‘I’m going to use artificial intelligence as the co-pilot to make an automated search.’…

What are the often invisible cognitive consequences of multiple sclerosis? Maureen van Dam mapped these out during her doctoral research. 'People usually notice the physical symptoms, but the cognitive symptoms deserve at least as much attention.'

Ben Wielstra strives to unravel the evolution of balanced lethal systems. On 1 February he started his own lab at the Institute of Biology Leiden. Wielstra is one of five researchers at Leiden University who has been awarded an ERC Starting Grant in 2018 by the European Research Council. ERC Starting…

In FameLab contestants explain their research to the public in a three-minute presentation – without using PowerPoint or other presentation tools. The Leiden heats of this international communications competition will be held on 7 March. Anyone is welcome to come and watch!

Delft, Nov. 15th, 2022 – Today, eight professors were simultaneously inaugurated as ‘Medical Delta professors’ at Leiden University, LUMC, TU Delft, Erasmus University and/or Erasmus MC. With an appointment of two or more of these five academic institutions, they combine technology and healthcare in…

Thanks to a clever research method, progress is being made in the quest for better tuberculosis medications. Within an American consortium that received a 30 million dollars grant, Leiden researcher Rob van Wijk plays a significant role. ‘The next breakthrough in tuberculosis research will come much…

The adventure of iGEM Leiden has come to an end. The result: prizes for Best Therapeutic Project and Best Model, a gold medal, a successful crowdfunding campaign and of course their open-source research findings, which are available for the scientific community.

Humans have influenced nature since as early as the Ice Age, and over the past century man’s impact has become even greater with our many new technologies and a growing world population. Leiden researchers study this impact and how we can keep it within reasonable limits so that nature can be preserved.…

With his dance routine and YouTube clips, he even manages to make grammar fun. His infectious enthusiasm and innovative teaching methods have won Thijs Porck, a lecturer in Old and Middle English, a nomination for the LUS Teaching Prize.

A team of researchers has managed to recreate the most natural skin cream in existence. Using the DUBBLE beamline (Dutch Belgian Beamline) at the European Synchrotron Radiation produced on the basis of the information identified, has the same properties as vernix caseosa. This cream may have a therapeutic…

Moving an electron microscope of 2000 kg is a delicate challenge. The highly sensitive instrument needed to be moved to a new measurement hall, but even a tiny bump could damage it. After a few nerve-racking weeks of preparing the move and reinstalment, the researchers finally have a verdict: the instrument…

Joost van den Vondel is considered to be the greatest Dutch poet and playwright of his time, but he certainly wasn’t the most popular. The 17th- and 18th-century public preferred to watch ‘Spanish theatre’. University lecturer Olga van Marion has written a book about this, together with Frans Blom (University…

Professor of Ecotoxicology Martina Vijver had planned an eight-week field work course for her students, but the corona virus threw a spanner in the works and Vijver had to come up with a new plan at short notice. ‘Without the help of my own network and that of my colleagues this would have been very…

Discovering effective new drugs is a long, expensive and uncertain process. Laura Heitman wants to improve this by finding out more about how drugs bind to proteins that play a role in disease. She calls it ‘drug discovery 3.0’. Inaugural lecture on 9 December.

Bringing together institutes and research groups, how do you do that? The Faculty of Science set up a joint research theme and financed three PhD positions. After four years, the profiling programme Endocannabinoids expires. ‘It really brought us together, and the collaborations remain.’