Investigating specific language and speech behaviour of people.

Dr. Foks obtained this fellowship for the project “Can promotion of efferocytosis induce regression of atherosclerosis?”, in which she aims to identify novel targets to promote regression of atherosclerosis. This research grant allows her to initiate independent research for the next three years.

A P300-based Brain Computer Interface character speller, also known as P300 speller, has been an important communication pathway, under extensive research, for people who lose motor ability, such as patients with Amyotrophic Lateral Sclerosis or spinal-cord injury because a P300 speller allows human-beings…

This dissertation provides an account of polar questions in Italian dialects from a typological, theoretical and empirical perspective.

The research described in this thesis focused on identifying novel drug targets and synergistic combinations for triple-negative breast cancer (TNBC), a virulent subtype of breast cancer with a dismal prognosis and limited therapeutic options.

In this thesis, we used genetically engineered mouse models to identify genes and pathways that are involved in ILC formation and in the development of resistance to FGFR-targeted therapy.

Promotor: P. J. J. Hooykaas Co-promotor: B. S de Pater

The research described in this thesis has, using the zebrafish as a model system, shed new light on the intricate relationship between TB and DM2, in particular on the role of leptin, SHP-1 and glucocorticoids.

Examining mediation and moderation.

Source: Purinergic Signal., Volume 10, Issue 3, pp. 441-53 (2014)

The master's specialisation Molecular, Cellular and Organismal Biology at Leiden University examines the molecular mechanisms underlying health and disease and how cells and organisms adapt to environmental factors.

PhD defence

The first of April was the official start of Phase II of the collaborative “PCAD4Cod”-project on the effect of sound on fish populations. Hans Slabbekoorn, associate professor at the IBL, is the principal investigator and collaborates with three PhD-students, Dr. Erwin Winter, (Wageningen Marine Research),…

Adva Eichengreen starts a fellowship focusing on enhancing social participation of deaf and hard-of-hearing (DHH) children. Eichengreen has been offered a postdoc position at Leiden University as part of the Marie-Sklodowska-Curie “LEaDing Fellows” Project within the collaboration of the Leiden-Delft-Erasmus…

Hans Slabbekoorn, researcher at the Institute of Biology Leiden, is one of the editors of the latest volume of the Springer Handbook of Auditory Research (SHAR). This book is filled with everything known about the effects of sound on vertebrates. Slabbekoorn’s contribution to the book as a co-author…

The Dutch Research Council (NWO) awarded behavioural biologist Hans Slabbekoorn (Institute of Biology Leiden) a grant of 750,000 euros to study fish and sounds around wind farms in the North Sea.

I think we should go this way. This way! THIS! WAY!! Making yourself heard in a city can be difficult. That is not only the case for humans, but birds seem to be hindered by urban noise as well. Researcher Hans Slabbekoorn of Leiden University already showed that great tits in Leiden communicate differently…

Promotor: P.M. Brakefield

Living systems scale from unicellular microbes to complex multispecies communities that constantly change over time. Within the theme Development & Disease, we enhance our fundamental understanding of development and homeostasis of living cells and systems. We analyze the normal situation and how stresses…

A novel in vivo model system for studies on glucocorticoid resistance

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The goal of hit and lead optimization is to optimize suitable chemical starting points that can modulate a drug target. The methods and technologies used are similar to those in Hit Discovery, but once the compound has shown activity in an animal model, it moves from 'hit' to 'lead.'

This project is aimed at 1) elucidating the role of attention in itch and pain, including orientation, and attentional disengagement (i.e., directing attention away) from itch and pain; and 2) modifiability of these attentional processes.

Herman Berkhoudt (former employee of the IBL, then EEW) organized the course, while Merijn de Bakker and Hans Slabbekoorn spoke about the latest insights in their disciplines.

IBL-researcher Katharina Riebel, together with international collaborators, published a remarkable finding in Nature Communications on the prevalence of female birdsong.

How do dissociative states affect the ability to suppress emotional distraction (in the context of a working memory task) in patients with Borderline Personality Disorder?

Molecular Physiology is a research group at the Leiden Institute of Chemistry dedicated to the design, synthesis and application of chemical tools to study important biological and biomedical questions. The group is headed by Prof. Dr. Mario van der Stelt and includes the research lines of Assistant…

In this research group, headed by Laura Heitman, novel receptor concepts in drug discovery are studied, aiming to increase the effectivity of medicines. Many drugs act via so-called G protein-coupled receptors (GPCRs) and therefore our research is mainly focused on understanding and improving drug-receptor…

The Risk and Regulation Lab from organises events and workshops in Leiden and The Hague. On this page you can read reports of the events that already took place.

When we are in a conversation, how do we know exactly when to respond, and how do we manage to respond so swiftly, yet without interrupting our interlocutors? Can speech melody – in particular utterance final “boundary tones” – help us determine who will speak next, or are these cues too late in the…

What are the genes and molecular mechanisms involved in bacteria-mediated plant drought tolerance?

Can a virtual character’s friendly non-verbal responses stimulate eye-contact in individuals with varying levels of social anxiety?

Research of the Methodology & Statstics unit of the Institute of Psychology at Leiden University.

Supervisor: Gerard van Westen

In this project, we aim to develop mathematical models to mechanistically and quantitatively predict the dynamics of cellular stress pathway activation and its relation with toxic effects when cells are exposed to various toxicants.

Cancer is the leading cause of death in the Netherlands, and, with over 100 different types of cancer, it’s not a simple disease. Today, skin, breast, lung, prostate and colon cancer are the most diagnosed forms. Therefore, the discovery and development of new drugs has the ability to significantly…

Social Information Processing in Children with and without Hearing Loss

This dissertation examines whether a cochlear implant provides congenitally deaf born children with sufficient auditory input to acquire low salient and syntactically and semantically complex functional items such as personal pronouns compared to their hearing peers.

Since the early 1990s, one can isolate the optical signal of a single molecule and single-molecule spectroscopy has quickly grown into an important research field.

Which plant leaf characteristics are involved in thrips resistance in tomato?

How do Chinese language teachers negotiate who they are as teachers when they work abroad? This dissertation offers clear, practice-oriented answers. It examines teacher identity - the everyday answer to 'What kind of teacher am I here?' - as it is reshaped through classroom interactions, institutional…

Key publications of the Medical Systems Biophysics and Bioengineeringgroup (Mashaghi Lab)

Bacteria caught red-handed, deeply frozen just as they were about to cause Lyme’s disease. Ariane Briegel is wildly enthusiastic about the wonders she observes thanks to three elements: a freezing technique, a camera-equipped microscope, and AI. ‘It’s fascinating. Every single cell is different.’

The CIGR comprises research groups from the Leiden Institute of Chemistry (LIC), the Leiden Academic Centre for Drug Research (LACDR) and the Leiden Institue of Physics (LION).

In this project, we plan to combine two strands of research in speech processing: (a) the impact of prosody on speech processing and (b) the impact of musical training on speech processing. In our project we will test 8 year-old children with different degrees of musical training: (a) primary school…

This research area is focused on the development and application of novel concepts and models in the emerging area of quantitative systems pharmacology (QSP).

The Physics and Biological and Soft Matter master's specialisation is one of the two programmes that Leiden University offers in experimental physics. This programme mainly focuses on Biological Physics and Soft Matters Physics.

Sasse, van Breen, Spears & Gordijn demonstrated an anger gap in response to sexism which was larger for women than for men and found evidence that expressed anger was associated with instrumental concerns.