Metastasis is responsible for over 90% of cancer-related deaths and arises from the ability of a small subset of tumor cells to detach from the primary tumor, overcome multiple biochemical and mechanical barriers, disseminate through the body, and colonize distant organs.

How do young adults find their way in an increasingly complex society? In Leiden, as part of the GUTS project, we study how brain development and self-regulation play a role in this process.

On 28 June 2018, Qiuyin Hu defended his doctoral thesis 'Regulating Working Conditions in Times of Globalization'. The doctoral research was supervised by Prof.dr. G.J.J. Heerma van Voss and Prof. dr. B. Barentsen.

The starting point for this research project is the notion that the human brain is susceptible to all kinds of fallacies and biases that affect our perceptions and influence our reasoning outside of our conscious awareness. Indeed, most people think they are merely observing facts and that they process…

This book presents a new framework for regulating human-like machines designed for emotional and sexual engagement, often powered by AI.

Salicylic acid (SA) is a plant hormone, which is involved in the defense responses to pathogens and to abiotic stress, and in the regulation of plant growth and development.

Nucleoid associated proteins maintain the architecture of the bacterial chromosome and regulate gene expression, hinting that their role as transcription factors may involve local three-dimensional chromosome re-modelling.

This book, written by two representatives of Leiden Law School, describes the framework of the European Insolvency Regulation (recast) (‘EIR Recast’), in force since June 2017.

Who had a say in making decisions about the natural world, when, how and to what end? How were rights to natural resources established? How did communities handle environmental crises? And how did dealing with the environment have an impact on the power relations in communities?

What is the role of emotion regulation in coping with interpersonal feedback?

On 18 June 2019, Neta Palkovitz Menashy defended her thesis 'Regulating a Revolution: Small Satellites and the Law of Outer Space'. The doctoral research was supervised by Prof. dr. P.M.J. Mendes de Leon and Prof. dr. G. Molier.

People are less willing to give up an interest when in a negotiation situation than when they can do it of their own free will, as Leiden University psychologist Eric van Dijk discovered. Knowledge of this kind can be used by policy makers, for instance, to motivate people to adopt certain desirable…

Promotor: R.C.M. Pelger Co-Promotor: G. van der Pluijm

A very large part of intravenously administered nanoparticles are cleared through the liver. Within the liver, most nanoparticles are thought to be sequestered by macrophages (Kupffer cells). To achieve effective cell-specific targeting of drugs and non-viral gene delivery vectors, improved mechanistic…

Learning is easiest out of interest. But interest is often multiple, and expands in various directions. How do you organize education accordingly?

On 12 September 2019, Michiel Rhoen defended his thesis 'Big Data, Big Risks, Big Power Shifts: Evaluating the General Data Protection Regulation as an instrument of risk control and power redistribution in the context of big data'. The doctoral research was supervised by Prof. G.J. Zwenne and Prof.…

How and when do interest groups organise themselves as transmission belts and what are the implications for their political relevance among public officials involved decision-making processes?

If a society is to be secure, sustainable and resilient, conflicting interests must be reconciled. Researchers at Leiden University study the behaviour of individuals, groups and states in relation to this issue, and use their knowledge to promote equality within and between communities.

Several so-called Special Interest Groups are linked to DSRP. These groups focus on specialized topics and organize their own group meetings, talks etc. Contact the group leader if you are interested to join. It is possible to be a member of multiple groups.

Are you curious about how health, behaviour and our living environment are connected? At Leiden University, you’ll explore how people grow up, age and live together in a changing world. From mental health to sustainable cities, from lifestyle to healthcare policy: you’ll learn to understand societal…

Are you curious about how health, behaviour and our living environment are connected? At Leiden University, you’ll explore how people grow up, age and live together in a changing world. From mental health to sustainable cities, from lifestyle to healthcare policy: you’ll learn to understand societal…

How do students’ interests develop over time and which interests are subsequently pursued in the higher educational choice of students?

Are you curious about how economics, law and governance shape our society? At Leiden University, you’ll explore financial systems, public administration, international relations and legal frameworks. From international law to public policy, from global diplomacy to financial regulation: you’ll learn…

Are you curious about how economics, law and governance shape our society? At Leiden University, you’ll explore financial systems, public administration, international relations and legal frameworks. From international law to public policy, from global diplomacy to financial regulation: you’ll learn…

How are children’s rights and welfare protected in the Dutch 'gezinslocaties' (family reception centres)?

How do interest groups in the Netherlands use strategic litigation to bring about political, social or legal change, and how does this strategy compare to other, more classical, ways to influence policy?

In this article, the authors explore why there is substantial cross-national variation in the level of regulatory clarity surrounding cryptocurrencies

Are you curious about how health, behaviour and our living environment are connected? At Leiden University, you’ll explore how people grow up, age and live together in a changing world. From mental health to healthcare innovation, from lifestyle to healthcare policy: you’ll learn to understand societal…

Are you curious about how health, behaviour and our living environment are connected? At Leiden University, you’ll explore how people grow up, age and live together in a changing world. From mental health to healthcare innovation, from lifestyle to healthcare policy: you’ll learn to understand societal…

How can we use data to better understand climate change? Can smart algorithms help drive medical breakthroughs? And how do you design technology that contributes to a more sustainable world? If you are curious about how the world works and how to solve complex problems using science, data, and technology,…

How can we use data to better understand climate change? Can smart algorithms help drive medical breakthroughs? And how do you design technology that contributes to a more sustainable world? If you are curious about how the world works and how to solve complex problems using science, data, and technology,…

In the late 19th and early 20th century, hundreds of thousands of Chinese labor migrants crossed the seas to the Dutch East Indies. On the tobacco plantations of northeastern Sumatra and in the tin mines of Bangka and Belitung, they endured long hours and harsh conditions. Their journeys formed part…

This book concentrates on the regulation of political parties in the EU post-communist democracies, and on Bulgaria, Croatia, the Czech Republic, Estonia, Hungary, Latvia, Lithuania, Poland, Slovakia, Slovenia and Romania, in particular.

The focus of the described research in this thesis is on the oxidative stress response (Nrf2 pathway). The aim of the research presented in this thesis is to obtain more information concerning microRNAs which are involved in the Nrf2 pathway, to determine and evaluate the application of microRNAs for…

In this thesis, we used genetically engineered mouse models and a variety of cell-culture based assays to identify genes and pathways that are involved in the development and treatment of invasive lobular carcinoma (ILC).

PhD defence

Are you curious about how societies are governed - and what makes a society just? At Leiden University, you’ll explore democracy, law, safety and public policy in both national and international contexts. From human rights to climate legislation, from elections to ethical dilemmas: you’ll learn to analyse…

Are you curious about how societies are governed - and what makes a society just? At Leiden University, you’ll explore democracy, law, safety and public policy in both national and international contexts. From human rights to climate legislation, from elections to ethical dilemmas: you’ll learn to analyse…

What if you could understand the world in the places where it truly begins – in language, in stories and in culture? In a time when countries clash, technology shapes what we see, and societies are changing fast, one thing is clear: you only really understand the news when you know what lies behind…