Metabolomics has the potential to play a pivotal role in understanding disease onset and progression, and ultimately personalized treatments. One of its major challenges is its large-scale implementation, which is necessary to deal with the high variability of the metabolome. In this work we have developed…

Developing robust and comprehensive analytical methods to size and quantify subvisible particles in biopharmaceutical products.

Whilst government’s ability to design ‘context-specific’ regional innovation policy is generally assumed to depend on the region’s decision-making power, the aim of this study is to investigate how regional government matters. In order to open up the black box of policy design, the study develops a…

Mensen worden steeds ouder. Soms in goede gezondheid, soms zijn er uitdagingen die de kop op steken. Met onderzoek, innovatief onderwijs en co-creatie met oudere mensen werken studenten van de master Health, Ageing and Society aan oplossingen voor deze uitdagingen.

What are the global relationships between environmental conditions and abundance of distinct types of mycorrhizal fungi in soil and plant roots?

This PhD subproject concentrates on 16th-century ichthyology and takes Gessner’s Historia piscium (1558) (further HP) as its point of departure and focus.

Across Europe, the need for a more dynamic governance and a better societal integration of research and innovation is increasingly appreciated. Internal drivers of change (such as the digitalization of science) and political will to better align with societal needs and concerns are bringing about aspirational…

This project aims to further understand the molecular details related to the biosynthesis and function of Galf containing glycoconjugates in fungal Aspergillus spp.

Law

Promotores: Prof.dr. H. van Veen & Prof.dr. W. de Boer (Wageningen University)

The mycorrhizal symbiosis is among the most widespread species interactions on Earth⁠. This thesis focuses on orchid mycorrhiza, a unique mycorrhizal type that has caught scientists’ attention for centuries⁠.

Mycorrhizas are symbiotic associations between soil fungi and most plant species.

Engineering an efficient microbial enzymatic polyethylene degradation pathway via an innovative combination of biochemistry and computational biology tools for enzyme discovery and characterization.

The central aim of LIPQUORUM is to unravel the intricate interkingdom signaling mechanisms between the Bacillus subtilis species complex and the devastating fungal pathogen Sporisorium scitamineum.

On the 12th of May, Stefan Norbruis successfully defended a doctoral thesis and graduated. The Leiden University Centre for Linguistics congratulates Stefan on this achievement!

The GMP Facility facilitates development and production of Advanced Therapy Medicinal Products (ATMPs) and chemical (peptide) synthesis.

A framework for prospective/ex-ante life cycle assessment (LCA) and ecological risk assessment (ERA) of emerging technologies is developed and applied to a case study of III-V/silicon photovoltaic panels.

How did the medieval manuscript develop as a physical object during the Twelfth Century Renaissance and what do these changes tell us about the intellectual culture of the period?

In this dissertation the author digs into the constituent elements of River Plate tango in order to decode how specific musical materials were organized and combined by four outstanding musicians: Pugliese, Salgán, Piazzolla and Beytelmann.

The work described in this Thesis is focused on the assembly of oligosaccharide fragments derived from a fungal polysaccharide, galactosaminogalactan (GAG) and fragments of the exopolysaccharide Pel, generated by Pseudomonas aeruginosa.

History lecturer Giles Scott-Smith is enthusiastic about the new pitch-to-peer programme (P2P), for which students have to make an original, creative assignment and evaluate one another’s work. This is part five in a series of articles about lecturers and innovation in teaching and learning.

Putting our interns to work’ is the third-year slogan for the Master’s Programme in Medicine at Leiden University. After their regular residency periods, students are encouraged to find an internship in demanding sectors where they would like to work after completing their studies. In the MasterMindsChallenge,…

An interdisciplinary photo exhibition about crafts and craftsmanship in different cultures will open at Oude UB on 6 October. At the opening Fridus Steijlen will give an introduction to the Tau Tau puppets that are made in Sulawesi, Indonesia.

Fungal infections pose a significant threat to individuals with compromised immune systems and despite advancements in diagnosis and treatment, they continue to jeopardize patient’s health.

Mycoheterotrophy is a particular mode of life in which plants obtain carbohydrates from their associated fungal partners, instead of by using photosynthesis.

The Leiden University Centre for Innovation and the Leiden University Medical Center (LUMC) have won the Surfnet Innovation Challenge. The team won the prize with an experiment to link a virtual 3D anatomical model to a living human body.

How do lecturer-researchers at Dutch Universities of Applied Sciences perceive their academic identity after expanding their teaching-only work portfolios to include researcher roles, and how do they navigate attached identity-based role transitions, while balancing personal goals, institutional expectations,…

Develop a prototype combined chemical-microbial enzymatical process for the sustainable, green recycling and revalorization of polyamides and polystyrene

Can furan-based resisn be degraded by microbial enzymes in combination with mild pre-treatment?

In order to keep pace with the demands of the 21st century and its rapidly changing work environment, students and professionals need to display a new, specific range of qualities. To cope with the changing job market, you have to be resourceful, resilient and reflective.

Microbial Sciences' contribution to the Bioactive Molecules research theme is to discover new bioactive molecules and enzymes and unravel their mechanisms of action, regulatory networks, and the (bio)synthetic pathways required for their production.

A number of calls for proposals have been launched to finance innovative educational projects. An overview is given below.

Uncover novel antimicrobials with prospective health benefits for sea turtles.

Feeling nostalgic, Professor in Public Administration Science Bernard Steunenberg explains how some years ago he would occasionally show a TV broadcast to his students, first removing the videotape from its big box and putting it in a VHS player. Today, a student from Maastricht, sitting in the train…

How can innovation help or hinder public procurement processes?

The eight ambitions of Leiden University's vision on education - Learning@LeidenUniversity - were the key theme of the packed Education Festival on 19 June. More than 200 lecturers and students came to PLNT, Leiden's innovation hotspot, for inspiration and best practices in the field of educational…

The Master of Medicine at Leiden University Medical Center (LUMC) has won the national biennial award for best educational innovation in medical teaching. It was awarded the prize by the Netherlands Association for Medical Education (NVMO) for its MasterMinds Challenge (MMC).

Attachés from the Innovation Attaché Network (IAN) visited Leiden University to meet with researchers working on Artificial Intelligence (AI) and to become more familiar with what Leiden, Leiden University and the LUMC have to offer to possible partners abroad.

This dissertation presents the results of the importance of creativity for ICT-students of Dutch universities of applied sciences (in Dutch: hogescholen), and the functioning of training courses that aim to promote creative abilities is highlighted.

In the research programme Microbial Sciences we perform state-of-the-art research in the field of biotechnology and microbial sciences.

Studies on the Disappearance of the Amphora Phenomenon

Broad universities that focus strongly on fundamental research have the best chance of contributing to economic innovations, for example in the life and data sciences. This is the message of Professor Simcha Jong in his inaugural lecture on 14 November.