Another research line is the development of a spatial CNS drug distribution model, by ultimately including the 3-dimensional anatomical organization of the CNS.

Stratigraphy, Palaeoenvironment and Archaeology of the Middle and Late Pleistocene Deposits.

Geology and Paleobotany of the Area surrounding the Archaeological Excavation at the Hazendonk River Dune (Western Netherlands).

The dissociative chemisorption of methane on metal surfaces is of fundamental and practical interest, being a rate-limiting step in the steam reforming process. The reaction is best modeled with quantum dynamics calculations, but these are currently not guaranteed to produce accurate results because…

Do medicines arrive in the right amount at the right spot in our brain? By making a model that depicts our brain in small 'brain blocks', Esmée Vendel tries to find an answer to this question. Her new, mathematical model predicts the concentration of medicines in the brain over time and space. Vendel…

Biodiversity is under pressure worldwide, but is essential for our health, food security and well-being. What is the influence of human actions on ecosystems? Can we provide biodiversity-inclusive solutions for our key societal challenges? These questions are central to the Biodiversity research the…

Through our research, we aim to enhance both scholarly understanding and practical knowledge in sustainability governance, while making meaningful contributions to the public debates on these critical issues. To achieve this goal, we embrace diversity in our research topics, methodological approaches,…

Supervisor: P.J.J. Hooykaas

The filamentous bacteria Streptomyces are widespread inhabitants of terrestrial soils.

The increasing resistance of pathogenic bacteria to antibiotics necessitates the discovery of new medicines.

A management strategy has been developed for field margins to reduce pesticide drift to non-target areas and to promote biodiversity on arable land. To this end, 3 and 6 m wide strips along the edges of winter wheat, sugar beet and potato crops have been left unsprayed with herbicides and insecticides…

The overall objectives of my thesis are to investigate the dynamics of the sorghum root microbiome and to explore the beneficial effects of the root microbiome on sorghum growth and stress tolerance.

Promotores: H.A. Udo de Haes, H.H.T. Prins, Co-promotor: H.H. de Iongh

Trust in public institutions in the Tata Steel case and beyond

Promotor: Prof.dr. G.P. van Wezel, Co-Promotor: E. Vijgenboom

Mycoheterotrophy is a particular mode of life in which plants obtain carbohydrates from their associated fungal partners, instead of by using photosynthesis.

Plants are colonized by an astounding number of microorganisms that can provide different life-support functions, including nutrient acquisition and protection against (a)biotic stresses like drought or pathogen attack.

Supervisor: P.J.J. Hooykaas Co-Supervisor: R. Offringa

Fieldwork is an essential part of this research and of course this part of the project is also a joint effort by citizen scientists and professional archaeologists. Discover when fieldwork will take place and how you can participate.

Paul Hudson, Associate Professor of Physical Geography at Leiden University College, examines human impacts on lowland rivers in his new book.

Corrie Bakels & Hans Kamermans (eds) (2009)

It is well-known that humans have significantly transformed ecosystems since their adoption of agriculture. However, in a deeper past, prehistoric hunter-gatherers may already have altered and modified their niche in ways that had major impacts on ecosystems.

The book ‘Pesticides and the Environment’ gives a transparent overview of facts and figures concerning pesticide use in the Netherlands and the impact of pesticides on the environment.

Promotor: G.P. van Wezel, Co-promotor: D. Claessen

Antibiotic-resistant bacteria pose a major health threat. Addressing this challenge requires among others the development of new antibacterial compounds. The research described in this thesis focuses on discovering novel antibiotics from soil bacteria, specifically Streptomyces and Paenibacillus.Despite…

We aim to unravel the molecular mechanisms involved in the transformation of eukaryotic cells by Agrobacterium.

Exploiting the Ecological Role of Natural Products as Novel Biocontrol Agents (LIPQUORUM): The central aim of LIPQUORUM is to unravel the intricate interkingdom signaling mechanisms between the Bacillus subtilis species complex and the devastating fungal pathogen Sporisorium scitamineum.

NIMAR facilitates and stimulates research and cooperation between the Netherlands, Morocco and third countries on the basis of equal partnership.

My PhD thesis investigates the ecological significance of resistance against drought-induced air bubble formation inside the water conduits of plants (embolism), and the plasticity and functional aspects of stem anatomical traits in woody and herbaceous species.

Agrian History, 5300 BC - AD 1000; C.C. Bakels

The Oral History project, as part of the Tell Balata Archaeological Park project, published an arabic-english booklet of local stories about the site of Tell Balata. An archaeological site near Nablus (West Bank).

'Skill, craft, and poiesis-intensive innovation' is written by Cristina Grasseni and is published in FormAkademisk.

The Garden Club is a ProParte sub-group.

The Public Entities of Saba and St. Eustatius commissioned two landscape biographies at the Dutch Cultural Heritage Agency (RCE).

The dissociative chemisorption of a molecule on a transition metal surface represents a rate-limiting step in many heterogeneously catalyzed processes, whereby most chemicals are made. In spite of the importance of this reaction, an accurate first principles approach to modeling it does not yet exist.…

We review the state-of-the-art in the theory of dissociative chemisorption (DC) of small gas phase molecules on metal surfaces, which is important to modeling heterogeneous catalysis for practical reasons, and for achieving an understanding of the wealth of experimental information that exists for this…

Sexuality is a fundamental part of being human. Yet, for many people with disabilities, it remains overlooked, unsupported, and surrounded by stigma. NWO-VIDI Sex, Care & Robots confronts that long-standing neglect with a project that envisions an urgent yet straightforward future: one in which sexual…

On this page you can find information about previous CCLS events.

To goal of this project is to get a deeper, more comprehensive and up to date understanding of the state of University-Business Cooperations (UBC) in Europe, from the perspective of both the Higher Education Institutions and the business sector.

The lysosomal β-glucosidase named glucocerebrosidase (GCase) is a retaining β-glucosidase that hydrolyzes the glycosphingolipid glucosylceramide (GlcCer) to ceramide and glucose at acid pH.

This dissertation investigates A'-dependencies in Standard German, Zurich German and Dutch where the dislocated constituent is indirectly, i.e. not transformationally, related to the position where it is interpreted. The analysis is carried out within the Principles & Parameters framework.

Despite the history of studies on methanol formation from CO2, the dominant elementary reaction steps that constitute the chemical mechanism for this catalyzed process are not determined.

In recent years, the use of primary data in terrorism research has increased. In order to maximise the benefits of this trend, we want to encourage terrorism scholars to implement open science practices more systematically. This article therefore presents different avenues towards open and reproducible…

The lipid membrane is a basic structural component of all living cells. Embedded in this nanometer-thin barrier, membrane proteins shape the membrane and at the same time respond to the shape of the membrane.

The lipid matrix in the stratum corneum (SC), the upper layer of the skin, plays a critical role in the skin barrier. The matrix consists of ceramides (CERs), cholesterol (CHOL) and free fatty acids (FFAs).

This monograph by Robert Ross provides a detailed narrative of the Kat River Settlement in the Eastern Cape of South Africa during the nineteenth century.

Key publications of the Analytical BioSciences and Metabolomics group

Catalysis is of extreme relevance in the production of everyday materials and plays a central role in many aspects of our life.