Promotor: G.F.A. Kersten, W. Jiskoot, Co-promotor: B. Metz

On December 9, 2016 Prof.dr. Ton Koopman will give a lecture 'Bach en zijn zangers' in the Pieterskerk in Leiden.

This thesis focuses on two processes involved in fighting infections: metabolism and immune cell motility and navigation.

Leiden University will be conferring three honorary doctorates in its special anniversary year. They will be awarded to Eliot Higgins, truth finder and founder of Bellingcat, Bonnie Honig, expert in feminist theory and legal theory, and Kelly Chibale, professor of organic chemistry, who works on prevention…

Promotor: C.A.M.J.J. van den Hondel, Co-promotor: Sandra de Weert

Promotores: A.H. Meijer, H.P. Spaink

Er is een nijpend cellen- en personeelstekort in Nederlandse gevangenissen. En dit is niet voor de eerste keer. Miranda Boone, hoogleraar criminologie en vergelijkende penologie, sprak met Trouw over de problematiek: ‘Het aantal gevangenen is het resultaat van beleid.’

In STAYAHEAD data-intensive approaches are being developed to ”decode the human immunome” with a focus on a global vaccine strategy. They have developed a rapid mass spectrometric test to analyse in real-time large numbers of variants of SARS-CoV-2 and the host immune response, and use these data to…

The outbreaks of AIDS and COVID-19 showed clearly how infectious viruses can influence people’s lives. Investigating the changes in the host metabolism may provide a paradigm shift to consider immune-metabolic interactions as therapeutic targets.

El viernes 3 de noviembre a las 11.15 tendremos el gusto y honor de escuchar a la Prof.dr. Sayak Valencia en el marco del X Congreso Internacional de la AHBx. Prof.dr. Sayak Valencia (Tijuana, Mexico, 1980) impartirá la segunda conferencia plenaria del X Congreso Internacional de la AHBx bajo el título:…

Mouse models are commonly used to assess the immunogenicity of therapeutic proteins and to investigate the immunological processes leading to antidrug antibodies. The aim of this work was to develop a transgenic (TG) Balb/c mouse model for evaluating the immunogenicity of recombinant human insulin (insulin)…

Large carnivores and humans, along with their livestock, have co-existed for thousands of years. However, human population growth and an increase in economic activities are modifying the landscape for large carnivores and their prey.

Op donderdag 20 februari organiseert Universitaire Bibliotheken Leiden (UBL) een workshop over prenten en tekeningen uit de collecties. In de workshop toont conservator Jef Schaeps bijzondere, bekende en onbekende prenten en tekeningen. Sommige behoren tot de grootste kunstschatten van de bibliotheek…

We investigate the processes underlying the patterns. We aim to explain biodiversity by investigating the distribution, function, development, and evolution of body forms, as well as physiological and behavioural variety among species. We collaborate with those specialized in describing, archiving,…

Nederlanders met lage inkomens lopen tot 1,5 keer meer risico op het krijgen van een hartaanval of beroerte dan rijkere landgenoten. Bij Surinaamse Hindoestanen is dit risico 1,9 keer hoger. Dat blijkt uit onderzoek van het LUMC en het HagaZiekenhuis. Nederlandse artsen kijken tot nu toe niet naar deze…

The Translational Immuno-Pharmacology group works on translating the efficacy of anti-infective therapy from preclinical (e.g. in vivo) to clinical, and is led by Rob van Wijk. Infectious diseases, such as tuberculosis, are in constant need of new therapies that work better, faster, and with less risk…

Uncover novel antimicrobials with prospective health benefits for sea turtles.

Antimicrobial resistance (AMR) is the phenomenon that pathogens become insensitive to the antibiotics that we use against them. A growing number of pathogens is becoming resistant, with methicillin-resistant S. aureus (MRSA) as the most famous example. But while the threat of AMR represents a slow-moving…

Promotor: Prof.dr. H.P. Spaink, Co-promotor: Prof. dr. A.H. Meijer

In this project, we will study the genetic and environmental drivers of woodiness and stem lignification at the level of plant‐to‐gene‐to‐molecule.

When foreign matter enters our body, our immune system has to make a choice whether or not to go on the attack. There are times when the system goes wrong, and we end up with an illness or an allergic reaction. Researchers at LUMC are trying to steer the immune system. The dossier on Immunity, Infection…

This study describes religion in Java.

De Faculteit Archeologie bestaat dit jaar 25 jaar. Ter ere van dit jubileum opende de faculteit op 1 maart zijn deuren voor het brede publiek.

Vice-President Vance uitte bij zijn recente bezoek aan Groenland kritiek op Denemarken. Trump had eerder al afstand genomen van Europa. Luuk van Middelaar, hoogleraar Grondvesten van de Europese Unie, en oprichter van het Brussels Instituut voor geopolitiek, deed een analyse over de situatie in Nieu…

Het rapport van de Commissie Sorgdrager naar aanleiding van de Hawija-zaak, wijst uit dat Defensie niet transparant is over eigen fouten. Wim Voermans, hoogleraar Staatsrecht, bevestigt in Nieuwsuur dat ‘Defensie een patroon laat zien van verkeerd en onjuist informeren van de Tweede Kamer.’

The Quantitative Pharmacology group headed by Coen van Hasselt focusses on the application of state-of-the-art quantitative pharmacometrics and systems pharmacology modeling combined with translational experimental models to develop personalized treatment strategies for antibiotics and to combat antimicrobial…

Tuberculosis causes 1.5 million deaths yearly and anti-tuberculosis therapies are threatened by emergence of drug resistance. Development of innovative drug combinations should be accelerated with the use of translational pharmacological models. Moreover, host-directed therapies (HDT), which stimulate…

This PhD-thesis analyses the relationship between the parties’ choices in the CPB Netherlands Bureau for Economic Policy Analysis’ assessments of the election manifestos and coalition agreements over the period 1986-2017, and tries to explain this relationship.

How did free agents oppose the monopolies held by the VOC and WIC in court?

This book offers a detailed analysis of social policy in Ecuador, covering its evolution over the past four decades. It examines how social relations and institutional frameworks have influenced concepts of well-being, the implemented policies, and the outcomes achieved.

On Thursday 30 May 2024 Corrie van Maris successfully defended a doctoral thesis and graduated.

How do plants lure microscopically small 'support teams' into their roots for protection against diseases? And what functions are activated in the microbes and the plants?

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Aspergillus niger is an important industrial producer of organic acids and enzymes producing large amounts of spent fungal biomass.

People who have taken antibiotics in the past three months pay more attention to negative facial expressions, according to research by postdoc Katerina Johnson and assistant professor Laura Steenbergen. This may explain how antibiotics increase the risk of developing depression.

The focus of the Antiviral Pharmacology group led by Anne-Grete Märtson is optimizing antiviral therapy for different viral infections by conducting clinical trials and using innovative computational and dynamic laboratory methodologies.

Antibiotic resistance, caused by widespread use of antibiotics, leads to bacterial infections that are difficult, if not impossible, to treat and is a major worldwide health concern.

Supervisor: P.J.J. Hooykaas

Atherosclerosis is a chronic inflammatory disease, and vaccination may be an attractive method to induce long lasting protection against endogenous factors that contribute to the development of atherosclerosis. We have shown that for example vaccination against modified LDL or interleukin-12 limits…