2,151 search results for “drug” in the Public website
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Regulators of integrin α6β4 function
This thesis describes our search to identify and understand possible regulatory mechanisms of integrin α6β4 in cell-matrix adhesion and intracelular signaling.
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Contact
Division contact information & address
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Myrtille Koerselmanm.e.koerselman@lacdr.leidenuniv.nl | 071 5276270
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Kostas Tassisk.tassis@lacdr.leidenuniv.nl | 071 5276302
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Leo Pricelsprice@lacdr.leidenuniv.nl | 071 5272727
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Marc Boefm.a.boef@lacdr.leidenuniv.nl | 071 5272727
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Nada Badrn.badr@lacdr.leidenuniv.nl | 071 5272727
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Bola Khalilb.a.a.khalil@lacdr.leidenuniv.nl | 071 5272727
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Matthijs Vlasveldm.p.vlasveld@lacdr.leidenuniv.nl | 071 5272727
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Linde Schoenmakerl.schoenmaker@lacdr.leidenuniv.nl | 071 5274607
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Daan Jiskootd.a.jiskoot@lacdr.leidenuniv.nl | 071 5272727
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Chiel Jespersm.jespers@lacdr.leidenuniv.nl | 071 5272727
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Rosan Kuinr.c.m.kuin@lacdr.leidenuniv.nl | 071 5272727
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Nasi Liun.s.liu@lacdr.leidenuniv.nl | 071 5276225
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Mark Fonteynem.fonteyne@lacdr.leidenuniv.nl | 071 5272727
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Martijn Moném.j.mone@lacdr.leidenuniv.nl | 071 5276105
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Martin Sichom.sicho@lacdr.leidenuniv.nl | 071 5274206
- Lunch Time Seminar: Applications of Artificial Intelligence in Early Drug Discovery
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Thomas Hankemeierhankemeier@lacdr.leidenuniv.nl | 071 5274226
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Annaloes Fokkelman-Klipj.e.fokkelman@lacdr.leidenuniv.nl | 071 5274496
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Kirsten Veltmanc.h.j.veltman@lacdr.leidenuniv.nl | 071 5272727
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Xiaobing Zhangx.zhang@lacdr.leidenuniv.nl | 071 5272727
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Lukas Wijayal.s.wijaya@lacdr.leidenuniv.nl | 071 5275706
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Sabine de Winters.de.winter@lacdr.leidenuniv.nl | 071 5272727
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Linglu Xul.xu@lacdr.leidenuniv.nl | 071 5276039
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Britt Duijndamb.h.a.duijndam@lacdr.leidenuniv.nl | 071 5272727
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Lucy Sinkel.j.sinke@lacdr.leidenuniv.nl | 071 5276039
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Mick van Schaickm.van.schaick@lacdr.leidenuniv.nl | 071 5272727
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Gerard Mulderg.mulder@lacdr.leidenuniv.nl |
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Arnoud Sonnenberga.sonnenberg@nki.nl | 071 5272727
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Natasha Tahirn.tahir@lacdr.leidenuniv.nl | 071 5275919
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Michiel van Dijkm.van.dijk@lacdr.leidenuniv.nl | 071 5274496
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Tamara Danilyukt.y.danilyuk@lacdr.leidenuniv.nl | 071 5275919
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Klara Beslmüllerk.beslmuller@lacdr.leidenuniv.nl | 071 5272727
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Elpida Lymperie.lymperi@lacdr.leidenuniv.nl | 071 5276039
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Vera van der Noordv.e.van.der.noord@lacdr.leidenuniv.nl | 071 5276225
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Johannes Schimmingj.p.schimming@lacdr.leidenuniv.nl | 071 5272727
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Ine Tijdenstijdens@lacdr.leidenuniv.nl |
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Chantal Pontc.pont@lacdr.leidenuniv.nl | 071 5276302
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Jurjun van der Veldej.j.s.van.der.velde@lacdr.leidenuniv.nl | 071 5272727
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Bart Lenselinke.b.lenselink@lacdr.leidenuniv.nl | 071 5272727
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A yeast screening method to decipher the interaction between the adenosine A2B receptor and the C-terminus of different G protein α-subunits
Source: Purinergic Signal., Volume 10, Issue 3, pp. 441-53 (2014)
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Anti-microbial and Anti-biofilm compounds From Indonesian Medicinal Plants
Promotor: C.A.M.J.J. van den Hondel, Co-promotor: Sandra de Weert
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Highly sensitive analysis using 3D cell culture model
A research goal for ABS is to develop miniaturized platforms for research in (stem)cell, in-vitro systems and application in clinical and preventive research. Combined with the high throughput, this development will make it possible to study the dynamics of pathogenesis in human and cellular models…
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Combined LC/MS-platform for analysis of all major stratum corneum lipids, and the profiling of skin substitutes
Ceramides (CERs), cholesterol, and free fatty acids (FFAs) are the main lipid classes in human stratum corneum (SC, outermost skin layer), but no studies report on the detailed analysis of these classes in a single platform.
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Nanoparticles and Microfluidics for Future Tuberculosis Vaccines
Tuberculosis is a major global health problem caused by the Mycobacterium tuberculosis complex, claiming more than a million lives annually.
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Skin Lipids: Localization of Ceramide and Fatty Acid in the Unit Cell of the Long Periodicity Phase
The lipid matrix of the skin's stratum corneum plays a key role in the barrier function, which protects the body from desiccation. The lipids that make up this matrix consist of ceramides, cholesterol, and free fatty acids, and can form two coexisting crystalline lamellar phases: the long periodicity…
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Liposome-based vaccines for immune modulation: from antigen selection to nanoparticle design
Nanoparticles can be used as delivery systems for both small molecules and macromolecules such as proteins, peptides or oligonucleotides. This thesis focuses on the use of liposomes, nanometric vesicles formed by a lipid bilayer enclosing an aqueous core. Liposomes are highly versatile delivery syst…
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Allosteric modulation by sodium ions and amilorides of G protein-coupled receptors
Promotor: A.P. IJzerman
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The effect of the chain length distribution of free fatty acids on the mixing properties of stratum corneum model membranes
The stratum corneum (SC) plays a fundamental role in the barrier function of the skin. The SC consists of corneocytes embedded in a lipid matrix.