Although exposure therapy is the gold-standard treatment of posttraumatic stress-disorder (PTSD), only half of the patients adequately benefit from it. Based on recent insights into the mechanisms of extinction, this project examines strategies and techniques to improve exposure treatment outcome in…

We present an extensive study of methods for exactly solving stochastic constraint (optimisation) problems (SCPs) in network analysis. These problems are prevalent in science, governance and industry.

Promotor: E.F.A. Deprettere, Co-Promotor: A.C.J. Kienhuis

Vandaag de dag liggen statistische methodes aan de grondslag van beslissingen in allerlei facetten van het leven, van de gezondheidszorg en agricultuur tot de financiële sector en marketing.

PhD defence

PhD defence

We aim to create an innovative e-learning and virtual reality training that helps healthcare providers to optimize placebo effects and minimizes nocebo effects via their communication.

Virtual Reality komt steeds dichter binnen handbereik van docenten en studenten. Hoe zou Virtual Reality kunnen bijdragen aan de leerervaringen van uw studenten? Vrijdag 19 februari, kwam een groep van ruim twintig docenten en experts af op een bijeenkomst over deze vraag in Studiecentrum Plexus. Met…

How can pupils and students learn to get a grip on complex 'swamp situations'? Inaugural lecture in abbreviated form held by prof.dr.ir. Fred Janssen on the acceptance of the post of professor of science education at Leiden University on 19 June 2017.

On December 6th, Bob Schoemaker succesfully defended his doctoral thesis and graduated. The Leiden University Centre for Linguistics congratulates Bob on this great result.

Als vertegenwoordiger behartig je de belangen van promovendi en ReMa-studenten binnen de Onderzoekschool Mediëvistiek. Zo krijg je onder meer de kans om mee te denken over het verbeteren van de onderwijs- en onderzoeksactiviteiten van de onderzoekschool. Interesse? Nog vragen? Neem contact op…

Automated Machine Learning (AutoML) is widely used to automatically build a suitable practical Machine Learning (ML) model for an arbitrary real-world problem, reducing the effort of practitioners in the ML development cycle for real-world applications. Optimization is a key part of a typical AutoML…

Machine Learning is becoming a more and more substantial technology for industry.

Promotor: Prof.dr. A. P. IJzerman, Co-Promotor: Dr. L.H. Heitman

uman skin equivalents (HSEs) are in vitro 3D-skin models that mimic many aspects of the native human skin (NHS) and can be a valuable tool.

Bispecific antibodies with one Fab arm binding to effector cells, such as T-cells and NK-cells, while the other Fab arm recognizing a tumor associated antigen (TAA) can be used to redirect these effector cells for tumor specific killing. Using bispecific antibodies to treat hematological cancers is…

Promoting academic equity for students with ADHD through evidence-based accommodations and inclusive teaching methods in higher education.

In this dissertation several settings in the Online Learning framework are studied. The first chapter serves as an introduction to the relevant settings in Online Learning and in the subsequent chapters new results and insights are given for both full-information and bandit information settings.

In this work we describe three methods to improve the performance of Quantum Field Theory calculations.

On Thursday, 4th October, Director of Education, Joanne Mol, received the qualification SKO (Senior Kwalificatie Onderwijs) This qualification not only recognises strong didactic and educational skills, but also proficiency in educational coordination and innovation. Joanne was the only staff member…

The next generation of high-contrast imaging instruments on space-based observatories requires sophisticated wavefront sensing and control in addition to a high-performance coronagraph.

The 14th International Global Optimization Workshop (LeGO 2018) was hosted by Leiden University in September.

On a structural level, the properties featured by a majority of mechanical metamaterials can be ascribed to the finite number of soft internal degrees-of freedom allowing for low-energy deformations.

Als universitair hoofddocent Ethiek en Digitale Technologie is zij verbonden aan het centrum voor Recht en Digitale Technologie (eLaw) waarvan ze ook hoofd onderwijs is. Daarnaast is Francien initiatiefnemer en coördinator van de universiteitsbrede minor AI & Society en neemt ze deel aan de universitaire…

We strive to address the challenge of constructing a modeling language to write software which can take advantage of recent hardware developments (multicore, cloud) without compromising in its abstraction levels.

This dissertation provides crucial but as yet missing empirical data on the tone accent opposition in the so-called

Promotor: Prof.dr. G.P. van Wezel, Co-Promotor: E. Vijgenboom

This dissertation provides a formal description of the relationship between diatopic/diachronic micro-variation and phonologization through analysis of the phonetic/phonological properties of unstressed vowel reduction and vowel insertion in two Northern Italian dialects.

Promotors: Prof.dr. T.H.W. Bäck, Prof.dr. B. Sendhoff (Technische Universität Darmstadt)

What are ‘missing links’ in research on teacher professional development trajectories? We focus on the role and development of teacher facilitators in designing and implementing (collaborative) professional development trajectories.

How can computers help design optimal buildings? PhD student Koen van der Blom makes algorithms that take into account all kinds of different architectural requirements, in order to reach the best compromise. And that is quite difficult: 'Algorithms do not automatically understand that a building that…

This thesis consists of two main parts. The first part (Chapters 2 and 3) deals with a class of Markov process called Quasi-Skipfree (QSF) processes.

NWO awarded a grant for novel research on Complex and Distributed Cyber-Physical Systems (CPS). The grant will fund a four-year research project in which they hope to devise a method to explore and find optimal designs for CPS. Todor Stefanov, Associate Professor at the Leiden Institute of Advanced…

Leiden Professor Marc Koper will be carrying out research on the chemical process underlying tin coating in order to optimise the quality of tin coatings. He has been awarded a subsidy of 285,000 euros from the STW Technology Foundation and Tata Steel.

David Versluis successfully simulated an infant gut virtually. This is crucial for research on improvements in formula milk. Currently, such research primarily relies on diaper contents, which is not optimal. Versluis defended his doctoral thesis on April 23.

This thesis investigates how quantum, quantum-inspired, and hybrid quantum-classical computation can enhance key points of the automated machine learning (AutoML) pipeline under the constraints of noisy intermediate-scale quantum (NISQ) devices.

The emergence of complex diseases resulting from abnormal cell-cell signaling and the spread of infectious diseases caused by pathogens are significant threats to humanity. Unraveling the dynamic mechanisms underlying cell-cell signaling and infectious disease spreading is crucial for effective disease…

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