Filamentous Actinobacteria, such as Streptomyces, produce a plethora of chemically diverse bioactive metabolites that have found applications across medicine, agriculture and biotechnology.

The symposium is open to all registered participants and consists of a one-day programme and a poster session.

Promotor: Prof.dr. A. P. IJzerman, Co-Promotor: Dr. L.H. Heitman

Promotor: P.G.L. Klinkhamer, Co-Promotores: K. Vrieling, P.P.J. Mulder

Promotores: Prof.dr. J. Kuiper, Prof.dr. P.H.A. Quax

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The current resurgence of whooping cough is alarming, and improved pertussis vaccines are thought to offer a solution. Outer membrane vesicle vaccines (omvPV) are potential vaccine candidates, but omvPV-induced humoral responses have not yet been characterized in detail.

G protein-coupled receptors (GPCRs), one of the largest families of membrane proteins, are responsive to a diverse set of physiological endogenous ligands including hormones and neurotransmitters.

β-Lactamases are enzymes that can break down β-lactam substrates, such as antibiotics, preventing the use of these antibiotics for the treatment of various infectious diseases. However, some compounds, β-lactamase inhibitors, can block these enzymes allowing for possible treatments using a combination…

This book examines the role of memory in animation, as well as the ways in which the medium of animation can function as a technology of remembering and forgetting. By doing so, it establishes a platform for the cross-fertilization between the burgeoning fields of animation studies and memory studie…

Structure-affinity relationship (SAR) and structure-kinetics relationship (SKR) studies were combined to investigate a series of biphenyl anthranilic acid agonists for the HCA2 receptor.

In most applications, electrocatalysts exhibit a large surface area to volume ratio, for example using nanoparticles.

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Lipid nanoparticles (LNPs) have enabled the success of mRNA vaccines but remain limited in broader therapeutic use by challenges in delivery efficiency, targeting, and mechanistic understanding.

Animal Sciences’ contributions to the Host-Microbe Interactions research theme focus on the interaction of animal hosts with pathogenic microbes but also the beneficial role of the gut microbiome.

PhD defence

Key publications of the Analytical BioSciences and Metabolomics group

Atherosclerosis is a progressive disease resulting in the formation of an arterial plaque. Despite lipid lowering, recurrent cardiovascular events remain a risk. While atherosclerosis is primarily lipid-driven, the immune system plays a critical role in the pathophysiology.

We perform multidisciplinary research at molecular, cellular, and organismal levels of animal biology to increase fundamental understanding of health and disease.

Due to the modern techniques of combinatorial chemistry and high-throughput screening, data on the biological activity of many millions of compounds is known. However, it is still very difficult to transfer this data into knowledge: if we know that compounds A and B bind to a certain protein with high…

This research delves into the unique cultural approach of the Tenggerese people, an Indigenous community in East Java, Indonesia, regarding elderly care. It focuses on their traditional practices of bakti (‘filial piety’) and sayan (‘mutual aid’), deeply ingrained in the community's lifestyle and va…

The different kinds of cultural perspectives on health and disease of the participants are related to their knowledge, beliefs, values and practices manifested in various forms of lifestyle in Indonesia. The cultural diversity of the population is also related to differences in health behaviour.

Promotor: Prof.dr. J. Memelink

Promotor: A.P. IJzerman Co-promotor: L.H. Heitman

Promotor: A. Kros

This thesis focuses on developing wafer-scale two-dimensional (2D) materials by combining synthesis, transfer, characterization, and device integration of graphene, hexagonal boron nitride (h-BN), and BN-doped amorphous carbon.

Single-layer graphene (SLG) has attracted considerable interest as a proton exchange membrane for direct methanol fuel cells (DMFCs), owing to its atomic thickness, mechanical robustness, and unique proton permeability.

The two-year Bioinformatics programme (120 EC) includes mandatory core courses and electives, as well as a Master's Thesis Research Project. PLEASE NOTE: The specialisation Bioinformatics will no longer accept new students after February 2026. If you're starting date is September 2026 or later, we…

Dutch political party VVD wants to set up a 'Mini Schengen zone' to control immigration better. But that is easier said than done, says Professor of European Law, Jorrit Rijpma.

Last Friday, more than a dozen people died during the storming of Spain’s North African enclave of Melilla. A dramatic incident, but certainly not the first time that refugees and migrants have used force to try to enter Melilla.

On Wednesday 23 September, the European Commission presented its new migration pact, where EU countries will have to improve cooperation in receiving and allocating migrants. Does this mean the end of refugee camps?

Europe is still trying to control migration to the continent. In doing so, it has to navigate between humanitarian ideals and public support.

Jorrit Rijpma responds in Dutch newspaper the Volkskrant to attention surrounding the reintroduction of border controls in the Schengen area.

Jorrit Rijpma visited Minsk (Belarus) on 11 and 12 September upon invitation by Nuffic Neso Russia

Eco-innovations like more economical cars do not generate the environmental benefits predicted by the manufacturers. This is the result of the so-called rebound effect, concludes Leiden industrial ecologist David Font Vivanco on the basis of new algorithms. PhD defence 3 March.

The research article ‘The life history of an enslaved African’ is one of the top 20 read Archaeometry articles in the period of January 2017 to December 2018.

Jorrit Rijpma, Associate Professor of EU law at the Europa Institute of Leiden Law School, has been named Jean Monnet Chair by the European Commission.

Beautiful microscopic specimens play the leading role in the course 'Biodiversity Plant' for first-year Biology students. Normally these are put back in storage right after the course. But not this year!

From the 11th of May Ewa Snaar-Jagalska has been appointed Professor in the field of cellular tumor biology within the Faculty of Science at the Institute of Biology Leiden. Her research focuses on the cellular tumor biology and human cancer modeling in zebrafish

The Urban Studies bachelor’s programme is based on two learning trajectories. One is dedicated to knowledge related to urban issues, while the other focuses on a wide range of practical and academic skills.

Industrial Ecology is the science of sustainability, a discipline which is vital to solving today’s environmental problems. In this two-year MSc programme, we are committed to training students who will go on to play instrumental roles in addressing and positively impacting the world’s sustainability…