Bacteria carry countless hidden treasures in their DNA: fragments that could hold the key to new medicines. But how do you pick out the most promising ones from millions of options? ‘Look at the switches that turn genes on and off,’ says molecular biologist Gilles van Wezel.

The thesis “De publieke prijs. Een onderzoek naar de verdeling van publiek geld via prijsvragen” (The public prize. A study of the allocation of public funds by way of competitions) was awarded the faculty Jongbloed prize 2016-2017 on 12 January.

Coronavirus is generating a great deal of uncertainty throughout the world. Fortunately, there are some bright spots, such as the residents of Italian cities who are in quarantine trying to keep everyone's spirits up with their clapping and singing. Closer to home, Leiden historian Suze Zijlstra took…

European Commissioner for Competition, Margrethe Vestager, gave a warning in the Europa Lecture on 14 June about large companies that abuse their power. 'An honest society begins with honest markets.'

Universities are there for future generations; how can we make sure we pass them on intact? Leiden academics responded to the address given by Cambridge professor Stefan Collini at the opening of the academic year.

Professor of Psychiatry Anne Speckens studied medicine in Leiden and did her psychiatry training there too. She opened the Radboudumc Center for Mindfulness in Nijmegen. What does she do there and how does she look back on her time as a student?

In the Phenomix Medical Delta Field Lab, which was officially opened on Thursday 9 July, scientists, healthcare institutions and businesses work together to develop innovative applications in the field of metabolomics. This research field makes it possible to determine which drugs will be effective…

Since 2008 every half a year an SBB student starts with an internship for Merck Serono Ventures in Geneva. Head of the company Roel Bulthuis selects and works with the SBB interns and shares his experiences as an employer. He is very pleased.

One of the holy grails of drug research is to be able to assess the safety of chemicals and pharmaceuticals without using laboratory animals. Researchers from Leiden University, among others, now receive a grant from the National Science Agenda to pursue that goal.

Destroying proteins from the Golgi apparatus of the cell in a controlled manner. That is the focus of chemist Marta Artola’s pioneering research. By developing a groundbreaking technology to target specific proteins in the Golgi, Artola aims to unlock new ways for drug development. For this ambitious…

How can Europe lead the way in vaccine development that is fast and for all? To answer this pressing question, Professor of Vaccinology Meta Roestenberg is holding a panel session on 14 July at the EuroScience Open Forum in Leiden.

Strengthening our contacts with Indonesia and exploring new opportunities for academic partnerships. These were the aims of a four-day visit to Jakarta and Yokyakarta at the end of February by a delegation from Leiden University.

Beads are among the oldest types of human artistic expression. Even so, the small ornaments have a bad status record regarding archaeological investigation. PhD candidate Mette Langbroek, usually at home studying early medieval beads, had the opportunity to work on a publication and exhibition on 5000…

From artificial intelligence to letters from the Dutch East Indies and from breast-cancer gene BRCA-1 to the collaboration between government and opposition: nine researchers from Leiden University have been awarded a Vidi grant for their research.

The Casimir Research School and the Graduate School Experimental Plant Sciences will be participating in the first Graduate Programme. This was announced on Wednesday 12 August by Minister Plasterk (Ministry of Education, Culture and Science). Leiden University is a partner in both schools. Nine Dutch…

The death of his grandfather in 1988 motivates Changsheng Wu to become a scientist. In 2016, he is awarded the C.J. Kok Jury Award for his thesis on novel antibiotics. Two years later, he will become a Professor at Shangdong University, at the age of 30 years.

Whispp, a Leiden-based speech technology start-up, is developing an app to help people who stutter express themselves more freely. Among those working together with Joris Castermans and his team at Whispp, are researchers and students from the Leiden University Centre for Linguistics (LUCL).

Care robots, medical treatments, deepfakes and self-driving cars all with the aid of artificial intelligence (AI). The BrAInpower exhibition at Rijksmuseum Boerhaave shows spectacular applications of AI and explains how it can make such huge leaps. Bas Haring, Professor of Public Understanding of Science,…

Portraits of six Leiden professors for whom 8 February 2016 was the first time that they took part in the procession of Leiden professors at the Dies Natalis.

‘Let us not forget the power of genuine engagement,’ dean Sarah de Rijcke stressed at the New Year's Reception on 7 January 2025, which was also attended by Rector Magnificus Hester Bijl and addressed the Faculty of Social Sciences.

Skåne University Hospital, Lund University and Leiden University Medical Center will work together to expand their research, teaching and development relating to Advanced Therapy Medicinal Products. That is the essence of a Memorandum of Understanding signed at SciLifeLab near Stockholm on Wednesday…

I am an associate professor in health psychology here at the Faculty of Social and Behavioural Sciences. My main line of work is health behaviour and behaviour change, so trying to understand why people do what they do including clearly unhealthy things. I have done a lot of work on personal goals and…

The doctor suggests opting for a treatment that is better for the environment. How do patients react to this? Doctors and psychologists together discovered that this has little impact on patient confidence in the doctor.

Multidrug-resistant pathogens and worldwide pandemics are increasing, making infectious diseases more prevalent. To develop new treatments, deeper knowledge of the interaction between bacteria and human cells is required. Ariane Briegel recently became a Medical Delta professor and studies such path…

Organs and tissues grown in the lab may in the future be able to cure people with organ failures. Micha Drukker, professor of Stem Cells, Developmental Biology and Technology for Innovative Drug Research, is convinced that the use of stem cells will make this possible. He will deliver his inaugural…

There are more molecules that could conceivably be candidate drugs than there are stars in the universe. How can we ever efficiently identify those molecules? Professor of AI and Medicinal Chemistry, Gerard van Westen: ‘I’m going to use artificial intelligence as the co-pilot to make an automated search.’…

Your local city park may be improving your health, according to a new paper led by Leiden environmental scientist Roy Remme. In Proceedings of the National Academy of Sciences Remme and his colleagues describe how access to nature increases people’s physical activity—and therefore overall health—in…

David Versluis successfully simulated an infant gut virtually. This is crucial for research on improvements in formula milk. Currently, such research primarily relies on diaper contents, which is not optimal. Versluis defended his doctoral thesis on April 23.

As of 1 May 2018, Nicole de Voogd has been appointed as Professor by special appointment Global change and marine ecosystems at the Institute of Environmental Sciences (CML). She is currently senior researcher at Naturalis Biodiversity Center in the field of tropical marine ecosystems.

The Leiden Institute of Chemistry (LIC) is to be joined by a further two talented young chemists. Bela Bode and Michele Pavanello have each won a Marie Curie subsidy. Bode will be studying electron transport in photosynthesis and Pavanello will be using computer models to study charge transport in large…

Sometimes an idea seems so logical and elegant at first glance, that you later wonder why no one thought of it before. Two researchers from LACDR have teamed up to develop a completely synthetic alternative to antibodies—one that mimics their size, shape and function, but which is cheaper, more stable,…

Thanks to a clever research method, progress is being made in the quest for better tuberculosis medications. Within an American consortium that received a 30 million dollars grant, Leiden researcher Rob van Wijk plays a significant role. ‘The next breakthrough in tuberculosis research will come much…

What does the future of quantum look like? Vedran Dunjko (Assistant professor at LIACS and LION) is co-founder of the applied quantum algorithms (aQa) leiden interdepartmental initiative research that will investigate this. They are part of the Quantum Delta NL consortium that was recently awarded substantial…

Dutch researchers are joining forces to conduct research together with a series of societal partners to keep the biological clock healthy in our modern 24-hour society. The BioClock consortium will receive a research grant of no less than 9.7 million euros for this. It is one of the projects that receive…

How can we prevent drug-induced liver and kidney damage? PhD candidates Marije Niemeijer and Lukas Wijaya investigated what happens in the cells during the onset of this damage: a stress response. Both focused on a different subtopic and made some interesting discoveries.

Bringing together institutes and research groups, how do you do that? The Faculty of Science set up a joint research theme and financed three PhD positions. After four years, the profiling programme Endocannabinoids expires. ‘It really brought us together, and the collaborations remain.’

Immunologist Leender Trouw specialises in the complement system, which is part of the immune system. In some diseases drugs help activate or inhibit this system. This is best done ‘in the right place at the right time’ − the title of his inaugural lecture.

‘By cleverly combining new techniques for analysing DNA at the level of individual molecules, we can achieve real breakthroughs in research into conditions such as dementia,’ predicts Professor John van Noort. Together with four leading biophysics research groups, he has written a review article in…

Herman Spaink knows of many substances that may help combat tuberculosis. Lab space to study them safely is very limited in Leiden. A brand-new lab at Universitas Gadjah Mada in Indonesia will soon provide a solution. About time, says Spaink, ‘The disease is on the rise and is becoming less sensitive…

In order to better understand the course of Alzheimer’s disease, Frédérique Kok believes that a strategic and structured approach is needed: the Mastermind research approach. With her LUF grant, Kok wants to generate high-quality data to build a mathematical model that can recognize the onset of the…

How do fats and enzymes in the brain contribute to multiple sclerosis? In his PhD research, Daan van der Vliet combined chemistry and neuroscience to gain new insights into how brain disorders develop.

The antibiotic EVG7, developed in Leiden, has proven capable of fighting the dangerous gut bacterium C. difficile with only a minimal dose. What’s more, the bacterium is far less likely to return, a major issue with existing antibiotics. The research was published in Nature Communications.

How do biological cells join forces to form a structure? In her PhD research, Daphne Nesenberend uses mathematics to show how forces and cooperation between cells create structure – and how simulations and experiments can reinforce each other.

From molecular ping-pong to cassava in the Amazon, and from extraterrestrial life to special antibodies. Twenty-five researchers from Leiden University have been awarded a Veni grant from the NWO. A grant of up to 250,000 euros will give them the opportunity to further elaborate their own ideas over…

PhD defence

Computers are increasingly able to accomplish tasks that are difficult for human experts, such as diagnosing diseases or detecting credit card fraud. While the earliest examples of computational thinking can be traced back to the 13th century, according to Holger Hoos, Leiden Professor of Machine Learning,…

Ten Leiden social and behavioural scientists have successfully applied for the NWO Open Competition. With this Open Competition, NWO gives researchers the chance to start small, high-risk, innovative or promising research projects.

In one in four criminal cases in the Netherlands, the court receives a report on the state of the defendant’s mental health. How is that information used exactly and what are the consequences? Scientific research has been lacking in this area. The PhD research of Roosmarijn van Es is a first step in…

More effective diagnosis and prognosis than ever, with less intrusive medical screening? Scientists from Leiden, Delft and Rotterdam are well on the way to achieving just that. Imaging professors Serge Rombouts and Wiro Niessen are working on an extremely rigorous, self-learning adviser for radiologists.…