958 search results for “cryo electron microscopy” in the Public website
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A physicochemical study of Medieval and Post-Medieval ceramics from the Aegean
Archaeometric analysis of glazed pottery assemblages from the Early Byzantine to the Early Modern periods in the Aegean.
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Nanoparticulate Impurities in Pharmaceutical-Grade Sugars and their Interference with Light Scattering-Based Analysis of Protein Formulations
PURPOSE: In the present study we investigated the root-cause of an interference signal (100-200 nm) of sugar-containing solutions in dynamic light scattering (DLS) and nanoparticle tracking analysis (NTA) and its consequences for the analysis of particles in biopharmaceutical drug products.
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NL-BioImaging AM
NL-BioImaging AM is a distributed research infrastructure aimed at promoting progress in the most cutting edge microscopy technologies and providing open access to these technologies to a broad community of academic and industrial users. All Netherlands bio(medical) microscopy centers participate.
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Towards artificial photosynthesis on the lipid bilayer of liposomes
Artificial photosynthesis has recognised potential to produce green and sustainable fuels from earth-abundant resources such as water, carbon dioxide (CO2), and sunlight.
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Biological, Soft and Complex Systems
The research groups within the biological, soft and complex systems research area study the physics of a broad range of biological and soft materials. This spans both experimental and theoretical research.
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Summer School: Frontiers of Modern Physics
This is the physics summer school of Leiden University. It is part of the Leiden Institute of Physics (LION). The summer school is intended for Bachelor (BSc) students in physics. It covers topics from quantum matter and optics, to biological & soft matter physics and cosmology and theoretical physics.…
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Optical Near-Field Electron Microscopy
PhD defence
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Spin-label EPR Approaches to Protein Interactions
Promotor: Prof.dr. E.J.J. Groenen
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A semisynthetic peptide-metalloporphyrin responsive matrix for artificial photosynthesis
This thesis is concerned with the constitution of chiral responsive matrix assemblies that may undergo light-driven conformational changes and self-select vibrations to develop vibronic states for driving semi-classical coherent transfer with nearly 100% yield in a lossless NCAP process.
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Between air and electricity : microphones and loudspeakers as musical instruments
This thesis investigated how microphones and loudspeakers could become musical instruments.
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The Chara plasma membrane system : an ancestral model for plasma membrane transport in plant cells
Multicellular giant algae Chara species have been widely used in physiological studies for decades.
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Opening Gorlaeus Building celebrated grandly
Confetti, stilt walkers and the new Einstein Fountain. On Monday, 2 September, the Gorlaeus Building of the Faculty of Science was festively opened. Together with Constantijn van Oranje, our students cut the ribbon. Dean Jasper Knoester: ‘The building is ready, now it is up to our students and researchers…
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Merijn de BakkerFaculty of Science
m.a.g.de.bakker@biology.leidenuniv.nl |
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Leiden research project on circular electronics receives 3.8 million euros from NWO
Fewer CO2 emissions, less airborne viral transmission, and a more sustainable form of food production: seven consortia of researchers and societal partners will put a budget of 32 million euros towards developing technological innovations. Important Leiden research on circular electronics by Prof. Dr.…
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Insulating phenomenon in superconductor
Leiden physicist Milan Allan and his group have discovered an apparent paradox within a material that has zero electrical resistance. They measured trapped charges, while charges should in theory keep flowing in the absence of resistance. The discovery could provide a missing piece of one of the big…
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Multiple Paths. Towards a Performance Practice in Computer Music
This thesis proposes multiple paths towards the development of a performance practice in Computer Music.
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The origins of friction and the growth of graphene, investigated at the atomic scale
Promotor: J.W.M. Frenken
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Stress-induced protein dynamic and growth arrest in C. elegans during development
During post-embryonic development into adults, animals face an environment that fluctuates constantly. For example, in nutrient availability, temperature, and osmolarity (e.g., salt concentration).
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New funding for advanced microscopy using gold nanorods
A consortium of researchers from the Leiden Institute of Physics (LION), the Institute of Biology Leiden (IBL), and the Leiden Institute of Chemistry (LIC) received a FOM program grant to develop a novel way of studying individual proteins inside a cell using gold nanorods.
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Aleydis Nissen publishes a feature article on the South Korean electronics industry
Aleydis Nissen published a feature article on the South Korean electronics industry in Eos magazine. The Pascal Decroos Fund sponsored this article.
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Fermions and Bosons: Excitons in strongly correlated materials
Promotors: Prof.dr. J. Zaanen, Prof.dr.ir. H. Hilgenkamp
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How Oncode-PACT is bringing new cancer medicines closer with 325 million in Growth Fund money
How can you ensure that more experimental drugs reach the finish line? At the moment, only one in twenty cancer drugs that are tested on humans makes it to the market. This is an enormous loss for patients and society. With a grant from the National Growth Fund, Oncode-PACT aims to efficiently select…
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Solution to distortion effect STM scanning
STM scanning experiments on poorly conducting materials are challenging, and can cause a distortion effect. A new model corrects for this effect, allowing physicists to better study materials in their quest to understand unconventional superconductivity. Publication in Physical Review B as Editor’s…
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Comparative wood anatomy and evolution of Apocynaceae and Sapotaceae
In my research, I used a comparative wood anatomical approach to address wood evolution of the (largely) tropical flowering plant families Apocynaceae and Sapotaceae.
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Atomic Insights into Hydrodesulfurization
Hydrodesulfurization (HDS) is an ubiquitous part of oil refining that ensures that fuels are cleaned of impurities and environment release of pollutants such as SOx and NOx gasses are minimized.
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Network flow algorithms for discrete tomography
Promotor: R. Tijdeman, Co-promotor: H.J.J. te Riele
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Parkinson’s protein α-synuclein: membrane interactions and fibril structure
The thesis describes the use of electron paramagnetic resonance (EPR) spectroscopy, in continuous wave and pulse modes, to address the interaction of α-Synuclein (αS) with membranes and the aggregation of αS.
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From droplets in the freezer to the inception of a potent new antibiotic
What started as an idea during a social gathering led to an unexpected breakthrough in research on resistant bacteria. Biologists and chemists from Leiden developed a new substance that proves to be effective against bacteria resistant to antibiotics. They published their discovery in Nature Chemist…
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Jasper’s Day – Six bike rides and a safari
On Monday 27 October, Jasper goes on safari in the Van Steenis building. And will he manage to stay dry more often than he gets soaked cycling between meetings? You’ll find out – along with the rest of Jasper’s day – in this column.
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Towards artificial photosynthesis: resolving supramolecular packing of artificial antennae chromophores through a hybrid approach
Promotor: H.J.M. de Groot
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The heart of oxygenic photosynthesis illuminated
Promotor: H.J.M. de Groot, Co-Promotor: A. Alia
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Bachelor Projects
Bachelor projects are available in
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Charge transport properties of Ru-complex molecules: the influence of humidity
I will give a general introduction to the field of molecular electronics, its history, methods and challenges. I will also introduce the subject of my investigation and provide a brief outlook to the remainder of our thesis.
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Surface and Interface Science
The nanoscale structure of a catalyst under reaction conditions determines its activity, selectivity, and stability. For the production of sustainable energy and materials, new catalysts are needed. By understanding the structure-activity relationships of catalysts under reaction conditions, insight…
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Environmental and health impact of informal e-waste recycling
The majority (80%) of e-waste generated globally are recycled informally in developing countries.
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The versatility of asymmetric aminoethyl-tetrazines in bioorthogonal chemistry
This thesis describes the synthesis, analysis of various tetrazine bearing compounds and use in bioorthogonal chemistry.
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Unfolding secrets of catalysts
To construct catalysts that can produce fuels from CO2 innumerable times, we need to learn much more about how catalysis works. Irene Groot is conducting groundbreaking research into catalysis at the atomic level.
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The Musical Work, Free Improvisation, and Live Electronics: Towards an Integrated Musical Paradigm.
Composer, bass player and ACPA alumnus Ilya Ziblat Shay presented a paper at the Music Weekend and Midlands New Music Symposium, organised by Nottingham Forum for Artistic Research.
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Understanding the Surface Structure of Catalysts and 2D Materials at the Atomic Scale
The work in this thesis demonstrates how to obtain an atomic-scale picture of a diverse set of complex surface structures observed using STM, under disparate conditions.
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New Year's Reception Faculty of Science
Conference
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Taking control of charge transfer: strategic design for solar cells
Promotor: Huub J.M. de Groot, Co-promotor: Francesco Buda
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Teaching
Research projects for students of the University of Leiden and other Dutch Universities are often available at the MacBio group. The research lines are also described in the Research section. For details of specific projects contact the supervisor (Ubbink, Dame, Boyle, Jeuken or Wentink).
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Pablo IlgemannFaculty of Science
p.m.ilgemann@cml.leidenuniv.nl | 071 5272727
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Jörg MeyerFaculty of Science
j.meyer@chem.leidenuniv.nl | 071 5275569
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Core Facilities
Core Facilities are shared resources that provide access to instruments, technologies and services to researchers across the Institute of Biology. They are staffed by scientists with vast experience in their field, ensuring that all researchers can count not only on the latest available technology…
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Milan Allan Lab - Understanding Quantum Matter
We are a dynamic research group at the Leiden Institute of Physics. Our aim is to explore and understand quantum materials, including strange metals, high-temperature superconductors, and quantum critical electron matter.
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Hybrid vesicles
Synthetic cells, also known as artificial cells or protocells, have wide ranging applications from drug delivery vectors to cell models. In biotechnology they can function as micro- or nanoreactors with possible applications in biocatalysis and photocatalysis. Phospholipids are by far the most commonly…
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Synthetic cells
Synthetic or artificial cells are vesicles, often lipid vesicles, with wide ranging applications from drug delivery to nanoreactors in biocatalysis. We are developing polymer-lipid hybrid vesicles for applications in compartmentalised biocatalysis, in which the polymer has been shown to greatly enhance…
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Synthetic, Physical and Computational Chemistry of Propeller-shaped Polycyclic Aromatic Hydrocarbons
This thesis systematically studies the physicochemical properties of non-planar, propeller-shaped, polycyclic aromatic hydrocarbons. The synthesis of several so-called propellerenes is described on a gram scale, using optimized procedures aimed at using less hazardous reagents and reducing the amount…
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Why Leiden University?
The Physics and Quantum Matter and Optics specialisation is one of the two programmes Leiden offers in experimental physics. The programme can be tailored to individual needs and interests.