3,072 search results for “cell mobility” in the Public website
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Dangerous microbes in lower level safety lab? A new technique could make it possible
Researchers need to work in specialized environments when they work with dangerous bacteria and viruses. These microbes spread easily, so only in labs with a high biosafety levels they can be studied. Unfortunately, to look at the microbes properly, expensive microscopes are needed that are not always…
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Looking at the big world of microbiology through the smallest lenses
Antoni van Leeuwenhoek, the father of microbiology, died 300 years ago. 2023 has therefore been designated the Antoni van Leeuwenhoek year. The new Unimaginable exhibition in Rijksmuseum Boerhaave is about the amazing world that Van Leeuwenhoek made visible. What was so special about the way he worked?…
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Making better use of our natural resources
The availability of natural resources, the energy transition, the importance of circularity and our dependence on China. This and more is what Professor of Industrial Ecology René Kleijn's inaugural lecture is about.
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Using statistics to prevent the loss of blood donors
The Sanquin blood bank gathers data on every donation. Around 720,000 donations are made every year. ‘That generates a mountain of highly valuable data,’ says Leiden PhD candidate Marieke Vinkenoog.
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'Working with PhD candidates gives me energy'
Erik Danen is the new Dean of the Graduate School from 1 January. He is a professor at the Leiden Academic Centre for Drug Research and conducts research into cancer drugs. Danen is really looking forward to it: ‘PhD candidates are a special group: that's what I like to dedicate myself to.’
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Eight researchers to travel abroad on Rubicon grant
Eight young researchers from Leiden University have received a Rubicon grant from the Dutch Research Council (NWO). This will allow them to conduct research at a top institute or university abroad.
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New SPARXS technique reveals DNA behaviour at unprecedented speed
Studying how single DNA molecules behave helps us to better understand genetic disorders and design better drugs. Until now however, examining DNA molecules one-by-one was a slow process. Biophysicists from Delft University of Technology and Leiden University developed a technique that speeds up screening…
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Sugar chemistry – Wouter Remmerswaal’s unrelenting pursuit of understanding
The dark matter of biology: clumps of sugar molecules that, for example, form sugary webs around pathogens. We know very little about them. Wouter Remmerswaal threw all his talent into the challenge – both in the lab and as a modeller – and succeeded. He received his PhD on 12th September.
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We finally understand how oxygen reacts on platinum
Platinum is a widely used catalyst, but its precise mechanism largely remains a mystery to scientists. Ludo Juurlink has now demonstrated for the first time how oxygen reacts on the platinum surface. Together with PhD students Kun Cao and Richard van Lent and international colleagues he publishes his…
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Six Leiden researchers receive ERC Starting Grant
Six researchers from Leiden University have received an ERC starting grant. This grant of on average 1.5m euros will enable the researchers to launch their own project, form their own research team and develop their best ideas.
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The role of bubble formation in sustainable hydrogen production
The sustainable production of hydrogen could potentially be made more efficient by adding a cleverly chosen salt to the process. Researchers at the Leiden Institute of Chemistry (LIC), in collaboration with physicists at the University of Twente, have discovered that the type of salt present in the…
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These are the seven Veni winners of the Faculty of Science
The Faculty of Science has received no less than seven Veni grants this year. Camila Correa, Max van Duijn, Stéphanie van der Pas, Sergii Pud, Mónica Varela Álvarez, Joseph Callingham, and Melissa McClure will receive a maximum of 250,000 euros to further develop their own research ideas over a three-year…
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New technique for Imaging Charge Transport in a Graphene Layered Cake
Leiden Physicists have developed a new technique to visualize electrical conductance in sheet-like nano materials. It shows great promise for devices based on a new family of materials—the ‘Van der Waals materials’. The physicists, who won the 2015 Dutch Vacuum Society prize for their work, present…
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DNA folded in compliant helix
In an Advance Online Publication biophysicist John van Noort and others show using magnetic tweezers that DNA is folded in compliant helices of chromatin. This allows enzymes access to the DNA needed for gene expression. Van Noort's research group made the discovery in close partnership with researchers…
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Robert Smit receives his PhD with distinction. ‘I am happy to be back in the lab’
An all-optical transistor, a molecule-sized sensor and a new kind of single-photon source for quantum communication. All dreamed applications of fundamental physics that are one step closer thanks to Robert Smit. On 12 June, he defended his PhD thesis with distinction.
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Personalised medicine? Then you’ll need to look beyond genetics
Why does a medicine work well for one person, but cause side effects in another? Research by Laura de Jong shows that it’s not just our DNA that matters – other medicines and illnesses can also affect how our bodies respond.
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Cracking the code: why platinum electrodes corrode
An atomic vandal has finally been caught! Scientists from Leiden University and the Department of Energy’s SLAC National Laboratory have uncovered the mysterious cause behind the rapid corrosion of platinum electrodes. This breakthrough paves the way for more affordable green hydrogen production and…
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Discoverer of the Year bridges science and medicine
Fascinated by science since high school, Alireza Mashaghi Tabari is driven to explore new ways of thinking in medicine. With a strong academic network, he educates students and gives public lectures. For his research at LACDR, he won the C.J. Kok Public Award 2018, making him the Faculty of Science's…
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Vidis for nine Leiden researchers
Nine talented Leiden researchers have been awarded a Vidi subsidy by the Netherlands Organisation for Scientific Research (NWO). Vidis are intended for researchers with several years of research experience who want to set up or expand their own line of research.
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Hundreds of fossil tree species belong to a single species
Paleobotanist Menno Booi discovered that 250 previously described fossil tree species are objectively not distinguishable; they belong to only one single species.
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How do children's kidneys eliminate drugs?
What dose of medicine do you give a child? That depends to a large extent on how quickly their kidneys remove the drug from the blood. For ethical reasons it is impossible to measure this directly in little patients. PhD candidate Sinziana Cristea combined different types of modelling and lots of data…
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Nutrition and fasting for the brain: why the Keto diet shows promise
Autism, Alzheimer’s, and bipolar disorder: can the development of these mental health conditions be influenced by the ketogenic diet? Increasingly, research suggests it might. 'For those it helps, it can be life-changing,' says neuroscientist Eline Dekeyster.
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Leiden scientists develop topological barcodes for folded molecules
The team of Alireza Mashaghi at the Leiden Academic Centre for Drug Research has found a way to determine and classify the shape of proteins. Their new theory defines the topology of proteins as a simple and precise barcode that allows the identification of all types of folds. ‘This barcode enables…
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Leiden celebrates establishment of new Chair in Science Based Business
By delivering his inaugural lecture titled ‘Where Science Meets Business,’ Simcha Jong accepted his appointment as Leiden’s first Professor of Science Based Business. In his lecture in the Large Auditorium of the Academy Building, Simcha argued that broad universities with a focus on fundamental research,…
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‘Make science communication more work and less hobby’
Young researchers met this month for the fifth Science Communication Summer School. ‘This is the first time some participants get to meet other researchers who also enjoy science communication. It’s great to see’, says Julia Cramer, one of the coordinators.
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‘Children’s healthcare rights deserve more attention’
‘Children’s rights are somewhat of a poor relation’, says Professor of Law and Health Mirjam Sombroek-van Doorm. In her inaugural lecture, she will emphasise how more attention needs to be paid to children’s rights in current thinking on law and health.
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Awaken sleeping antibiotics with ERC Advanced grant
To facilitate the search for new antibiotics. That is the aim of Gilles van Wezel, professor molecular biotechnology at the Institute of Biology Leiden (IBL). He wants to do this by looking at similarities in the DNA of antibiotic-producing bacteria. Van Wezel has been awarded an ERC Advanced grant…
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Bacteria inside plant roots battle fungal disease
Two bacterial species team up inside the plant root system to rescue their host from fungal infection. This was discovered by a team of microbiologists and bioinformaticians from the Netherlands Institute of Ecology, Wageningen University, and the Institute of Biology Leiden. They also identified the…
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New potential cancer drugs and where to find them
Cancer research generates massive amounts of data, but traditional tools often fail to fully harness their potential. How can we unlock this data to provide better treatments for cancer patients? PhD candidate Marina Gorostiola González explored this by using advanced data analysis techniques to guide…
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Studying ferritin: ‘we hope this will eventually give more insight into Alzheimer's’
Martina Huber, Jacqueline Labra Munoz research Alzheimer's disease. They study ferritine, iron storage in the brain. An inbalance of iron could play a role in this form of dementia.
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Teachers' Academy fellows making teaching more attractive and more effective
On 29 October, seven innovative lecturers from different faculties will join the existing ten fellows of the Leiden Teachers' Academy. The current fellows have been engaged for the past year in implementing their innovation projects. How are these progressing?
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Online education in the lecture hall
Everything around us is in motion. Students, the University, technology, society, the labour market and the world. These developments provide an impetus to experiment with new forms of education. This article samples a small selection of the many dozens of innovative educational projects. What is striking…
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NKI-AVL and LUMC are joining forces in immunotherapy
Strengthening a cancer patient's own immune system so that the body itself can better destroy cancer cells. This is at the heart of immunotherapy, the most promising progress in cancer treatment in recent years. In order to drive this development further, the Netherlands Cancer Institute-Antoni van…
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New cellular imaging paves way for cancer treatment
A new technique using fluorescent imaging to track the actions of enzymes might aid drug design for new anti-cancer, inflammation and kidney disease treatments. Researchers at the University of York and Leiden University have published these findings in Nature Chemical Biology.
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Stories from women in physics: ‘I want to understand how the world works’
For the International Day of Women and Girls in Science, women students and researchers from physics talk about what inspires them about their work. From quantum to cosmology and biophysics, their curiosity about how nature works is what connects these women. What do these 5 scientists want to share…
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PhD-vacancy at the IBL on the neurogenomics of vocal learning
This project on the role of FoxPs in vocal perception and production learning is part of nine PhD-positions funded by the NWO Gravitation Programme which was granted to the Dutch Research Consortium 'Language in Interaction'
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‘Doing a PhD is never boring!’ How Guido Stam built a microscope that can measure bacteria without causing harm
A microscope with incredible sharpness that leaves samples unharmed – Guido Stam helped develop one. During his PhD research, he combined light and electrons to study biological samples. ‘We can now measure things that simply weren’t possible before.’
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From bubbles to fuel: could this special soap film soon enable artificial photosynthesis?
A soap film with chemically distinct sides: it's the latest breakthrough in the research led by chemist Sylvestre Bonnet. This unique soap film, along with an innovative device capable of continuously producing new soap films, forms a crucial piece in the puzzle for the development of artificial pho…
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Consensus, bias and polarisation: How mathematicians study opinions
How do opinions form and change in large groups of people? That's not just a sociological question, it's a mathematical one. PhD candidate Federico Capannoli studied opinion dynamics. He defended his thesis on November 19.
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The hunt for selective drugs
How do you ensure that a drug has an effect on the right protein – and nothing else? Chemist Anthe Janssen explored various methods for determining the selectivity of potential medicines. He also looked at the substance BIA 10-2474, after a man died in a French clinical trial in 2016. PhD defence on…
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The first of April was the official start of Phase II of the collaborative “PCAD4Cod”-project on the effect of sound on fish populations.
The first of April was the official start of Phase II of the collaborative “PCAD4Cod”-project on the effect of sound on fish populations. Hans Slabbekoorn, associate professor at the IBL, is the principal investigator and collaborates with three PhD-students, Dr. Erwin Winter, (Wageningen Marine Research),…
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A computational tool that will transform bacterial genome analysis
Whether a microbe is beneficial or harmful to a plant can now be predicted with high accuracy thanks to bacLIFE. This bioinformatic tool with an intuitive interface makes it much easier to unlock the secrets of bacterial genomes. A group of Leiden biologists presented it in Nature Communications.
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The surgeon who wants to make her operations unnecessary
Lotje Zuur sometimes has to perform disfiguring operations. As a head and neck surgeon, she removes parts of the mouth, throat or face of people with cancer. Now a promising treatment may make such operations unnecessary. What would this mean for patients? This is what her inaugural speech on 19 September…
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Decomposing tears in order to detect Dry Eye Disease
By measuring proteins in tears, ophthalmologists can more easily diagnose dry eyes (Dry Eye Disease). Peter Raus, a Belgian ophthalmologist and PhD student at the Institute of Biology Leiden, developed a new method for protein determination in tear fluid. The technique is also promising for the early…
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Ben Wielstra about newts, bizarre evolution and Naturalis
Newts of which half of the offspring die before birth. Evolutionary biologist Ben Wielstra is investigating how this can exist in nature. In his research he collaborates with Naturalis Biodiversity Center.
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Hans Slabbekoorn appointed professor: 'There are still gaps in our knowledge'.
Hans Slabbekoorn is specialised in animal sounds. On 1 July, he was appointed professor of Acoustic ecology and behaviour. A great honour, according to the new professor. ‘This job never gets boring, whether I am investigating the urban jungle or marine noise.’
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Artificial intelligence as the co-pilot for drug discovery
There are more molecules that could conceivably be candidate drugs than there are stars in the universe. How can we ever efficiently identify those molecules? Professor of AI and Medicinal Chemistry, Gerard van Westen: ‘I’m going to use artificial intelligence as the co-pilot to make an automated search.’…
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Untangling the Evolution of a Balanced Lethal System
Ben Wielstra strives to unravel the evolution of balanced lethal systems. On 1 February he started his own lab at the Institute of Biology Leiden. Wielstra is one of five researchers at Leiden University who has been awarded an ERC Starting Grant in 2018 by the European Research Council. ERC Starting…
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FameLab: young scientists take the stage
In FameLab contestants explain their research to the public in a three-minute presentation – without using PowerPoint or other presentation tools. The Leiden heats of this international communications competition will be held on 7 March. Anyone is welcome to come and watch!
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With 30 million dollars, this consortium aims to tackle tuberculosis
Thanks to a clever research method, progress is being made in the quest for better tuberculosis medications. Within an American consortium that received a 30 million dollars grant, Leiden researcher Rob van Wijk plays a significant role. ‘The next breakthrough in tuberculosis research will come much…