How many men and women die per year at the hands of others? What are the motives behind these killings? Are there as many homicides today as years ago? How can we explain the rise and fall of homicides over time? And: What is the influence of (early) childhood and adolescence on the likelihood to commit…

This article describes the phenomenon of firearms violence and the importance of including non-lethal firearms violence in understanding this phenomenon.

Because of their large surface area and immunological competence, mucosal tissues are attractive administration and target sites for vaccination.

The group Clinical Neurodevelopmental Sciences has expertise in individual differences in child development, in particular the development of psychopathology, ranging from mild to severe neurodevelopmental disorders.

Do recent developments in the European security architecture signal the end of multilateral cooperation, or the beginning of a new era with emerging forms of international security collaboration?

The last decades it is increasingly recognized that acute as well as chronic postoperative pain is an important problem. Treatment and prevention of postoperative pain is a challenge, especially in special patient populations where there is only limited guidance on how to optimally use opioids.

Pharmaceutical companies, governments and the general public have become increasingly aware that animal models used in drug testing lack vital aspects to serve as an accurate representation of human biology. As models of the human body should become more physiologically relevant, animal models no longer…

In Luganda, the widest spoken minority language in East African country Uganda, the word for photographs is Ebifananyi. However, ebifananyi does not, contrary to the etymology of the word photographs, relate to light writings. Ebifananyi instead means things that look like something else. Ebifananyi…

On 5 September, Elize de Mul defended the thesis 'Digital Döppelgangers: identity in the Culture of Imagination'. The doctoral research was supervised by Simone van der Hof and Esther Keymolen.

Why do certain incidents of serious violence end lethally whereas others do not? What role do personal characteristics of offenders and victims play and how do immediate situational factors influence outcomes?

Promotor: Jan van der Greef; Co-promotors: Mei Wang; Eduard van Wijk

According to the amyloid cascade hypothesis, accumulation of beta-amyloid (Aβ) peptides initiates the pathological cascade in Alzheimer's disease (AD).

If you wish to know exactly what is going on in a healthy or sick human body, and at various levels such as molecule, cell, tissue, organ, larger systems and a person as a whole? Do you wish to learn how to do research which contributes to diagnoses, treatment and prevention of diseases? Then the bachelor…

Misinformation has emerged as a major societal concern. But why do citizens contribute to the dissemination of falsehoods online?

The research described in this thesis shows that hypercholesterolemia, a well-established risk factor for atherosclerosis, can impact skin lipid pool and barrier function already at young age. In the field of atherosclerosis, we showed that the small peptide Lyp-1 can be used as a targeting molecule…

The Institute of Security and Global Affairs (ISGA) is a scientific institute that specialises in security issues.

This article presents a systematic review aiming to provide a comprehensive overview of cybersecurity training methods and assess their effectiveness.

Promotor: J.W.M. Frenken

Promotor: Prof.dr. R. Verpoorte, , Co-Promotor: Young Hae Choi

Marieke Liem, Professor Social Resilience and Security at Leiden University, and Katharina Krüsselmann, PhD candidate at Leiden University and Manuel Eisner mapped the flow of homicide cases with the help of a systematic review.

In this article, Wout Broekema, Wouter Jong, and Sara Perlstein explore the design and assessment of crisis inquiries from a learning perspective.

Binnen de masteropleiding Education and Child Studies kun je verschillende typen stages lopen.

Systems pharmacology aims to apply techniques from systems biology to pharmacological models.

Promotor: C.A.J. Knibbe, Co-promotores: H.P.A. van Dongen, B. van Ramshorst

Proteases degrade matrix molecules in the atherosclerotic plaque, thereby reducing atherosclerotic plaque stability. Mast cells, that contain proteases such as tryptase and chymase, have been identified at the site of rupture in specimens of human coronary arteries and their number in the plaque was…

Technological advances have an impact on our daily lives. They have also been employed by governments to manage border security, especially at controversial border crossings. Fences, heat sensors, heat cameras, drones and other hi-tech equipment that are currently being tested collectively produce a…

This article introduces the concept of Repertoires of Comparison (RoCs) to explain how certain comparisons become deeply embedded in social and political life.

Intergenerational transmission refers to the complex and dynamic process with which values, ideas and behaviors are transmitted across generations. We are specifically interested in the intergenerational transmission of behaviors and beliefs that might result in harm to the individuals involved or society…

In recent years, the use of primary data in terrorism research has increased. In order to maximise the benefits of this trend, we want to encourage terrorism scholars to implement open science practices more systematically. This article therefore presents different avenues towards open and reproducible…

Prematurely born neonates require, amongst others, pharmaceutical therapy. Dosing guidelines for these therapies are often based on data from term born neonates or older infants, while these are not necessarily similar to prematurely born neonates.

There is accumulating evidence for an increase in severe global drought events. In particular, Europe experienced several severe droughts in 2003, 2015, and 2018 (unprecedented in the past 2,110 years). Such droughts have caused serious and far-reaching impacts on terrestrial ecosystems.

In populations with a seed-bank, individuals can temporarily become dormant and refrain from reproduction until they can become active again. The repository of all dormant individuals in the population is called the seed-bank. Seed-banks are observed in many taxa, including plants, bacteria and other…

It is the aim of this project to better understand how the physical properties of lipids influences the structure and overall barrier function of the skin.

Biopolymer sequencing with graphene edge-based tunnel junctions has the potential to overcome current limitations with the third generation of sequencing based on biological nanopores.

Inactivating mutations in BRCA1 or BRCA2 genes predispose to several types of cancer.

Homicide engenders broad moral concerns in society, and its aftermath can be understood as a barometer for criminal justice policy. Of all homicides committed, however, only some lead to arrest, to prosecution and ultimately to conviction in court.

Dr. Pauline Aarten tries to find answers of the impact a road traffic accident has on the victims and surviving relatives and how we can improve their position.

Does Artifical Light at Night (ALAN) disrupt seasonal physiological and behavioral patterns in migrating freshwater fish?

In this article, Marieke Liem and Kim Moeller revisit Goldstein’s framework on the drugs-violence nexus

Promotor: Prof.dr. T. Hankemeier, Co-promotor: T.H. Reijmers

This new article by Monica Kaminska is part of a special issue for Journal of Cybersecurity, based on a selection of contributions from THe Hague Program for Cyber Norms' 2019 Conference.

In this article, Bart Schuurman and Sarah Louise Carthy explore the distinctions between radicalised individuals and the general population

Promotor: Prof.dr. F.S. de Boer, Co-promotor: D. Clarke

This thesis describes the structural and biochemical characterization of the β-lactamase BlaC from Mycobacterium tuberculosis (Mtb), and the Alr and YlmE proteins from Streptomyces coelicolor A3(2).Mtb is the main cause of tuberculosis.

Filamentous Actinobacteria, such as Streptomyces, produce a plethora of chemically diverse bioactive metabolites that have found applications across medicine, agriculture and biotechnology.

On 1 February 2018 Nathalie-Sharon Koster defended her doctoral thesis ‘Crime victims and the police’. The doctoral research was supervised by Professor J.P. van der Leun and M.J.J. Kunst.

This article investigates how parenthood serves as a critical turning point for young people in Latin America, influencing their criminal trajectories.

This article provides an in‐depth assessment of lone actor terrorists’ attack planning and preparation.

Developmental and Educational psychology is concerned with the developmental course and dynamics of cognition, self-regulation, and emotional competence, and the implications for educational and clinical practice.

The HOPES study is one of the largest investigations of this kind to date! By studying existing brain scans and data collected form over 4,000 14-25 year olds, the project team hopes to identify specific changes in the brain that make young people vulnerable to suicidal thoughts and behaviours.