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Sarah de Rijcke has been awarded Wellcome funding to study and promote responsible research practices

Atherosclerosis is the most prominent underlying pathology of cardiovascular disease and an important cause of major adverse cardiovascular events.

The potential of liposomal cancer vaccines

Key publications of the Biologics Formulation group

Promotores: Prof.dr. E.A.L. Biessen, Prof.dr. T.J.C. van Berkel

Promotor: W. Jiskoot, Co-promotor: A. Hawe

Cardiovascular disease is the leading cause of death worldwide.

Promotor: C.A.J. Knibbe, Co-promotor: J.J. Boelens, R.G.M. Bredius

Animal Sciences’ contributions to the Host-Microbe Interactions research theme focus on the interaction of animal hosts with pathogenic microbes but also the beneficial role of the gut microbiome.

In our globalised economy, goods and services are frequently produced abroad. Is it the producer or the consumer that should be held responsible for greenhouse gas emissions associated with production? Together with colleagues from Berlin, Hauke Ward of the Institute of Environmental Sciences (CML)…

The current COVID-19 vaccination campaign involves injecting the vaccine into muscle tissue, but injecting a smaller amount of vaccine in the skin might also provide good protection. The #wakeuptocorona crowdfunding campaign has enabled Anna Roukens (LUMC) to examine the safety and efficacy of vaccination…

Leiden professor of Cellular Immunology of Parasitic Infections Maria Yazdanbakhsh receives the prestigious NWO Spinoza Prize this year. This, in many ways, border-crossing scientist contributes with her research to more effective vaccines against parasitic infections and better medication for inflammatory…

On March 5, CWTS and the Leiden University Data Science Research Programme will organize the symposium ‘Fairness and Transparency, towards responsible data science’.

The shift from response to recovery is now noticeable as the world moves past the paralyzing effects of the COVID-19 pandemic. This book explores responses to the pandemic by international, regional, and local institutions, multilateral action, and crisis prevention efforts at different levels of governance,…

The United Nations Office for Disarmament Affairs (UNODA) has published the 2017 issue in their Civil Society and Disarmament series, titled Voluntary, Non-Binding Norms for Responsible State Behaviour in the Use of Information and Communications Technology: A Commentary. The series aims to provide…

The Project “Excellence in science and innovation for Europe by adopting the concept of Responsible Research and Innovation (NewHoRRIzon)” sets out to promote the acceptance of RRI in Horizon 2020 (H2020) and beyond. It will work out the conceptual and operational basis to fully integrate RRI into European…

In this article Vanessa Newby discusses how the ANZUS states of United States, Australia, and New Zealand that sit on the fringes of the Asia-Pacific, are increasingly using their armed forces to deliver Humanitarian Aid and Disaster Response (HADR) as a way of engaging with the region.

What are we referring to when we talk about ‘good work’? And what does it mean to be a good employer? Helen Pluut and Merel Cornax address these questions in a recently published editorial.

Anyone in Leiden wanting to join a student association has plenty to choose from. But the risk of alcohol abuse is a very real one. Leiden University, Leiden University of Applied Sciences and dozens of student associations have signed a new alcohol covenant that promises they will do their best to…

We have followed the UK referendum of Thursday, 23 June 2016, with great interest and indeed concern.

How can you increase the effectiveness of inspectors using responsible artificial intelligence (AI)? This is the question the Innovation Center for Artificial Intelligence (ICAI) Lab AI4Oversight is tackling. By developing algorithms and methods, they try to provide optimal support for, for example,…

Physics and Engineering Approaches to Biomedicine and Pharmacology

International organisations that represent collaborations between States are becoming increasingly more powerful, and they have an increasing impact on our daily lives. For example, the European Court of Human Rights in Strasburg established that minors have a right to legal aid immediately following…

In this project we think about the relationship between territory and contagion. Tracing the historical, political, and conceptual linkages between territorial bordering and migration on the one hand and disease related phenomena like contagion, immunity, and inoculation on the other, we ask how the…

Many Humanities scholars keep a blog of their own. This summer, we’re putting these in the spotlight. For this week’s interview, we sat down with dr. Florian Schneider of the Politics East Asia blog.

Light can be used to apply forces on single cells. Focused lasers have been used by physicists to tweeze particles and to manipulate them. These so called “optical tweezers” can be used as mechanical phenotyping tools for characterising the mechanics of materials and living objects.

With cancer, a person’s body cells grow uncontrollably. Putting together a detailed picture of how this comes about makes it possible to develop efficient therapies. Researchers at the Leiden University Medical Centre (LUMC) and Leiden University are working together to gain a better understanding…

Tuberculosis is a major global health problem caused by the Mycobacterium tuberculosis complex, claiming more than a million lives annually.

The Translational Immuno-Pharmacology group works on translating the efficacy of anti-infective therapy from preclinical (e.g. in vivo) to clinical, and is led by Rob van Wijk. Infectious diseases, such as tuberculosis, are in constant need of new therapies that work better, faster, and with less risk…

Glycoconjugate vaccines are composed of microbial poly- or oligosaccharides covalently linked to a carrier protein.

Dr. Foks obtained this fellowship for the project “Can promotion of efferocytosis induce regression of atherosclerosis?”, in which she aims to identify novel targets to promote regression of atherosclerosis. This research grant allows her to initiate independent research for the next three years.

The image of the European Union (EU) as a remote law-making machine is widespread. Quite often journalists and politicians deliberately depict ‘Brussels’ as bureaucratic, even undemocratic, bypassing its citizens. And many of us buy into that image. Nikoleta Yordanova, Anastasia Ershova and Aleksandra…

This thesis focuses on the application of lipid-based nanomedicine in drug delivery, including small molecular antitumor drugs and biomacromolecules including mRNA, and evaluates their biological performance.

The aim of the REACT Study is to examine whether baseline inflammation, and/or neuro-immune responses to stress in a sample of adolescents with experiences of childhood adversity predicts: the perception of stress, social behaviour and general mental and physical health during and after the COVID-19…

The Ghent Rolin-Jaequemyns International Law Institute (GRILI) is a research institute within the Faculty of Law at Ghent University. Founded in 2015 at the initiative of Prof. Tom Ruys, the Institute brings together the existing expertise within the law school in the broader international law domai…

The Leiden Centre of Science and Techonology Studies has developed 10 principles that are intended to guide the responsible use of university rankings.

PhD defence

Leiden researchers have developed a groundbreaking model to advance cancer immunotherapy. Using a 3D printer, they create mini-tumors within an environment that closely mimics human tissue. They have also developed a method to monitor real-time interactions of these mini-tumours with immune cells during…

From 5 – 7 November the The Hague Program for Cyber Norms will take place at Het Spaansche Hof in the Hague. The theme this year is Behaviour in Cyberspace: Novel Horizons.

Pharmacologist Amanda Foks is one of the ten talented scientists who received a Dekker grant from the Hartstichting. She receives €427,000 to find a way to rejuvenate immune cells to prevent infarcts. Foks was nominated as Discoverer of the Year in 2016.

An overview of the research at the Biologics Formulation group

At the division of Biopharmaceutics, we aim to develop and test new therapeutic approaches to limit or even prevent the development of atherosclerosis in order to reduce the number of acute cardiovascular syndromes such as myocardial infarction or stroke.

In STAYAHEAD data-intensive approaches are being developed to ”decode the human immunome” with a focus on a global vaccine strategy. They have developed a rapid mass spectrometric test to analyse in real-time large numbers of variants of SARS-CoV-2 and the host immune response, and use these data to…

The Leiden University Medical Center (LUMC) is committed to improving healthcare and the health of individuals. The LUMC staff put this mission into practice on a daily basis with their leading research, cutting-edge teaching and optimal, innovative healthcare.