Salma Balazadeh, Víctor Carrión, and Jos Raaijmakers, biologists at the Institute of Biology Leiden (IBL), have successfully applied for an NWO grant and got awarded 730.000 euros. The board of NWO Domain Applied and Engineering Sciences awarded funding for their project within the Open Technology Programme…

Bacteria whirl around in the mouths of most people, forming dental plaques and sometimes causing nasty gum infections. Treponema denticola might be a dangerous pathogen, but not much is known about this bacterium. It was up to Ariane Briegel and her research group to change that.

Using artificial intelligence to find new antibiotics. With that, researchers from Leiden University are nominated by magazine KIJK for the Best Tech-idea of 2021. From September 14 onwards people can vote to crown one of the nominees as the winner.

'What nature made isn’t necessarily an optimized medicine to use in the human body,’ says Professor of Biological Chemistry Nathaniel Martin. That’s why a group of Leiden researchers is making a chemistry-based improved version of the frequently used antibiotic vancomycin. They received an NWO NACTAR…

Taking probiotics can help reduce negative feelings. This is shown by research by Katerina Johnson and Laura Steenbergen published in the journal npj Mental Health Research. They also investigated which people benefit most from these ‘good’ bacteria.

The challenge is considerable, but so is the satisfaction when it succeeds: creating complex sugar molecules that play a role in biology.

Biologist Nataliia Machushynets felt like she was ‘looking for a needle in a haystack’, trying to find new antibiotics to help solve the problem of resistance. During her PhD research, she did find what she was looking for, in the soil beneath our feet.

Identifying novel antibiotic compounds to tackle antibiotic-resistant bacteria. Researchers from Leiden University and VU Amsterdam will unite through a project now funded by NWO’s Open Technology Programme (OTP), which awarded the collaboration nearly one million euros.

Leiden's iGEM team has won high honours at the Grand Jamboree in Paris. The biology students came second in the Overgraduate category with their project PHAse Out. They also took home awards for Best Biomanufacturing Project, Best Wiki and Best Entrepreneurship as well as a Gold Medal. To top it all…

The European Research Council (ERC) has awarded Nathaniel Martin a Proof of Concept (PoC) grant. With it, his group aims to make a dangerous but potent antibiotic less toxic. He receives €150.000.

In De Kookshow, Universiteit Van Nederland explores the scientific world behind food. Ever wondered which senses influence how tasty you find something? And why do you always have room for pudding after a meal? Leiden historian Kim Beerden is among the scholars providing answers.

To facilitate the search for new antibiotics. That is the aim of Gilles van Wezel, professor molecular biotechnology at the Institute of Biology Leiden (IBL). He wants to do this by looking at similarities in the DNA of antibiotic-producing bacteria. Van Wezel has been awarded an ERC Advanced grant…

More and more people worldwide have infections caused by bacteria that are resistant to many types of antibiotic. Why is this and how big of a problem is it?

Four researchers from Leiden University have been awarded NWO Open Competition grants in the Science domain. This is for research into subjects such as immune cells in tumours, antibiotic resistance and magnetic semiconductors.

Everything biobased: Plastic, medicine and fuel. It seems like a futuristic utopia. But for how long? A collaboration of researchers now proposes an idea to accelerate the development process. By combining machine learning and laboratory automation, this biobased ideal may become a reality rather sooner…

Effectively treating a severe case of pneumonia is often challenging. Identifying the pathogen behind it can be difficult. PhD candidate Ilona den Hartog tried something new: ‘We searched for answers in substances our own body produces.’ PhD defence on 17 September.

The dark matter of biology: clumps of sugar molecules that, for example, form sugary webs around pathogens. We know very little about them. Wouter Remmerswaal threw all his talent into the challenge – both in the lab and as a modeller – and succeeded. He received his PhD on 12th September.

Good research means looking beyond disciplinary boundaries, said Professor of Molecular and Cellular Biochemistry Remus Dame in his inaugural lecture on 10 May. Processes that take place on DNA shouldn’t only be researched in a test tube but also in living cells, for instance.

Herman Spaink knows of many substances that may help combat tuberculosis. Lab space to study them safely is very limited in Leiden. A brand-new lab at Universitas Gadjah Mada in Indonesia will soon provide a solution. About time, says Spaink, ‘The disease is on the rise and is becoming less sensitive…

Antibiotic resistance is a common problem among patients. The European Project TIPAT trains pharmacologists, microbiologists and immunologists of six universities in interdisciplinary thinking. The ultimate goal is to develop better treatment guidelines to combat resistance. Coen van Hasselt of the…

Why are mycobacteria such successful pathogens? And are there defence mechanisms in the body that help reduce an infection? To find out, Annemarie Meijer has been awarded the NWO Open Competition ENW-XL grant. She will not explore this quest alone. Five other leading Dutch research groups are participating…

Two Leiden Science researchers received an NWO-XS grant for their research. Both projects are highly promising, but also high-risk. Macrophages that trap bacteria and data storage made from 2D materials convinced the board of their potential.

Tracking mucus-eating bacteria, mapping the complexity of planetary nebulae and a signalling pathway in cancer. These three Leiden projects have been awarded Open Competition Science-M funding by the Dutch Research Council.

From a new generation of antibiotics and more-effective vaccines to a map of dark matter and new light on Hindu traditions. Four researchers from Leiden University have received a prestigious €2.5m ERC Advanced Grant to develop their research.

De crèche en het klaslokaal zijn misschien wel de meest gunstige plekken voor ziekteverwekkers. Toch is er relatief weinig bekend over hoe kinderen reageren op virussen en bacteriën en hoe het komt dat sommige kinderen veel beter beschermd zijn dan anderen. Simon Jochems, onderzoeker aan het Leids Universitair…

“Is it possible to restore antibiotic sensitivity in resistant bacteria?” Dr. Tingjie Guo wondered. “Watch me and learn”, phage responded. Dr. Tingjie Guo received an open competition XS domain ENW grant from the Dutch Research Council (NWO) to investigate the evolutionary trade-off of antimicrobial…

She studied biology in Leiden and never left. Now, as Professor of Immunobiology, Annemarie Meijer has taken on the role of the new confidential counsell for for PhD candidates. It's a role that suits her perfectly: she has extensive experience in the research world and has guided dozens of PhD candidates.…

An international research team is to search for invisible life in the Galápagos Islands. The diversity of bacteria and other microscopic organisms may not be evident to the naked eye, but it is essential to nature. To the islands' giant daisies, for instance: unique endemic plants that are currently…

Human resources

The opportunity to explore a new, exciting research topic. That is how Lennart Schada von Borzyskowski describes his successful application for the NWO XS grant. It comprises 50,000 euros, which the researcher from the Institute of Biology Leiden (IBL) will spend on investigating a more sustainable…

Sixteen researchers at Leiden University are to receive a Veni grant from the Netherlands Organisation for Scientific Research (NWO). These awards offer promising young researchers the opportunity to further develop their own ideas over a period of three years.

What is the best way to restore dune ecosystems? The project TERRA-Dunes researches the role of soil microbes in the development of natural dune areas. Recently, the project went into a new phase: planting 412 oak seedlings grown in different type of soils.

Paco Barona Gomez is the newest associate professor at the Institute of Biology Leiden (IBL). The Mexican researcher is fascinated by the evolution of natural products: compounds made by microbes, but also plants and animals. ‘It’s like we investigate chemical dark matter.’

Dutch mosquitos are more resilient to saltwater than previously thought. Environmental scientist Sam Boerlijst discovered this during his PhD research at the Hortus botanicus. This knowledge is crucial for understanding how mosquito-borne disease transmission might change in the future.

In the complex academic playing field, it is crucial that researchers and research support professionals know how to find each other. At Leiden University, these collaborations are indispensable too, say professor Gilles van Wezel and project manager Mariana Avalos Garcia. ‘Without support, this project…

In Sci-Fi comic book Resist NOW!, wondrous adventures will illustrate possibilities to combat antimicrobial resistance. But the comic book will only be produced if enough money is raised to make the project into reality.

Four university medical centres, including the LUMC, are joining forces to increase pandemic preparedness in the Netherlands.

What hidden nature is there in our cities and how can we use such organisms? This is what the HiddenBiodiversity project will be exploring over the next four years. The project’s kick-off meeting was held at the Hortus botanicus on Monday 26 September.

The Dutch Research Council (NWO) has granted four grants to Leiden humanities scholars. They get to spend this money on research on a topic of their choice, without thematic preconditions.

Leiden University joins the Just Transitions for AMR Working Group, an interdisciplinary team of social science and humanities researchers who are exploring ways to mitigate the growing threat of antimicrobial resistance in a just and equitable manner, with due consideration to the human rights of present…

Op zaterdag 3 juni vindt de Museumnacht Leiden plaats. Ook dit jaar zijn Leidse wetenschappers en studenten onderdeel van de programmering.

From medicines from snake venom to supercrops and the origin of words. Thirteen researchers from Leiden University will receive Open Competition XS grants from the Dutch Research Council (NWO).

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PhD defence

Sander van Kasteren only noticed some small, subtle changes since he was appointed professor on 1 May. Still, he has to get used to the idea, even though he had been working towards the professorship for a few years. ‘I don't quite see myself as a professor yet.'

Due to the increasing resistance to certain antibiotics, the life-threatening condition sepsis is becoming harder to treat. For her PhD project, Leiden pharmacologist Feiyan Liu used mathematical modeling to find out how antibiotics can be used more effectively to cure sepsis.

Ilze Bot wants to reduce the prevalence of cardiovascular diseases. Her research focuses on mast cells, which protect us from infections but can also make us ill.

The Dutch East India Company (VOC) took healthcare seriously, albeit mainly for business reasons. Former GP Ton Zwaard’s PhD research reveals that although healthcare in Asia was well organised, the VOC faced persistent problems for two centuries.

Through various initiatives, Leiden University is trying to make people aware of the importance of biodiversity: the cultivation of a wide variety of micro-organisms, animals and plant species. This is important because in the Netherlands biodiversity has declined from about 40 percent in 1900 to about…

From pipetting in the lab to shining in front of the camera at a global student event. With 8.000 viewers watching the livestream, Marjolein Crooijmans presented the iGEM Giant Jamboree in Paris.