The genetic material of currently living Europeans is partly of Neandertal origin. Were our ancestors successful because they were hybridising and interacting with the local populations they encountered when migrating into new places? This subject takes centre stage in a beautiful documentary produced…

From malaria parasites as a vaccine to how top-level bureaucrats reach their decisions: seven researchers from Leiden University have received a Vidi grant from the Dutch Research Council (NWO). This 800,000-euro grant will enable them to develop their own innovative line of research over the next five…

A major new study of ancient DNA has traced the movement of people into southern Britain during the Bronze Age. In the largest such analysis published to date, scientists examined the DNA of nearly 800 ancient individuals. Publication in Nature on December 22, 2021.

SAILS and CAIRELab, the LUMC’s AI expertise centre, recently held an event that gave healthcare professionals and computer scientists the chance to meet. The meeting proved fertile ground for new collaborations.

Does medicine make patients feel better or worse? We are getting better at predicting this from people’s DNA profiles, says Professor Jesse Swen. ‘It never fails to fascinate me how one DNA base pair can have such a huge effect on treatment with medication and the outcome.’

Imagine scanning lion dung or a mouse dropping and instantly knowing exactly what and how much the animal has eaten. Thanks to new DNA techniques, this is becoming increasingly feasible. PhD student Kevin Groen tested how effective these techniques are at unraveling the diets of wild animals.

Tuberculosis bacteria survive by hiding in our immune cells. In her PhD research, biologist Salomé Muñoz Sánchez explores how boosting the body’s own defenses might outsmart this deadly pathogen. Her work reveals two key proteins that help immune cells destroy the bacteria.

Not experiments and lab coats, but computers and artificial intelligence: this year's Nobel Prize in Chemistry went to the inventors of the groundbreaking AI model, AlphaFold. This programme accurately predicts protein structures based on their genetic code—a crucial step in understanding biological…

The Board of Governors is pleased to announce that Professor Cisca Wijmenga has been appointed by outgoing Minister of Education, Culture and Science Robbert Dijkgraaf as its new member.

RARE-NL, a new collaboration between university hospitals, hopes to find treatments for rare diseases. Professor Teun van Gelder is representing the LUMC in the initiative.

There seem to be genes that influence how our brains develop over time. A large international consortium has discovered this with an extensive study. The results of the study were recently published in Nature Neuroscience.

Leiden's iGEM team has won high honours at the Grand Jamboree in Paris. The biology students came second in the Overgraduate category with their project PHAse Out. They also took home awards for Best Biomanufacturing Project, Best Wiki and Best Entrepreneurship as well as a Gold Medal. To top it all…

Sixteen researchers at Leiden University are to receive a Veni grant from the Netherlands Organisation for Scientific Research (NWO). These awards offer promising young researchers the opportunity to further develop their own ideas over a period of three years.

Ten Leiden researchers have been awarded a Veni grant by the Dutch Research Council (NWO). The grant, of up to 280,000 euros, will enable them to elaborate their ideas over a period of three years.

A group of biology students are working on a solution to the world’s plastics problem by getting bacteria to make biodegradable plastic.

Bacteria carry countless hidden treasures in their DNA: fragments that could hold the key to new medicines. But how do you pick out the most promising ones from millions of options? ‘Look at the switches that turn genes on and off,’ says molecular biologist Gilles van Wezel.

If an echo (or ultrasound) shows that a foetus has a heart or other defect, parents face difficult decisions. Then an idea of their child’s shorter and longer-term future is literally a matter of life and death. Haak will argue in her inaugural lecture that the cohort studies of rare diseases that are…

Several consortia in which Leiden University is involved have been awarded Dutch Research Agenda funding. Leiden is the coordinator of five of these consortia. These five consortia will receive grants worth a total of almost 24 million euros. They relate to interdisciplinary projects that will bring…

Rapid developments in DNA techniques allow researchers to find out more and more about human genetics. An international group of scientists has drawn up five ethical guidelines to ensure that this DNA research is better regulated. Leiden archaeologist Marie Soressi – one of the signatories - explains…

Researchers at LUMC have made a breakthrough in understanding PALB2 mutations, an important cause of hereditary breast cancer.

Studying how single DNA molecules behave helps us to better understand genetic disorders and design better drugs. Until now however, examining DNA molecules one-by-one was a slow process. Biophysicists from Delft University of Technology and Leiden University developed a technique that speeds up screening…

Researchers from Leiden University Medical Center (LUMC) have discovered how malaria parasites escape the immune system of mosquitoes. The so-called QC enzyme changes proteins on the outside of the malaria parasite such that the immune cells are unable to recognise the parasite. As a result, the parasite…

From historical understandings to new treatments: during the Public Day of the Leiden Institute for Brain & Cognition, curious visitors learned how rapidly research into brain disorders is evolving. ‘I found the neurosurgery and the research on organoids on chips particularly fascinating.’

In a new study published in PLOS One, Leiden archaeologist Anastasia Nikulina, together with an international team from France, Denmark, the United Kingdom and the Netherlands, challenges the long-held belief that early humans had minimal impact on their environment before the rise of farming.

Microorganisms that temporarily ‘go to sleep’ play an important role in the evolution and survival of a population. Mathematician Shubhamoy Nandan conducted research on the effect of this characteristic called ‘dormancy’ in a novel mathematical model.

Leiden University has awarded its prestigious University Medal to Emeritus Professor Lex van der Eb. As a pioneer in genetics and molecular biology, he received this honour for his services to science and his key role in the development of the Leiden Bio Science Park (LBSP).

The Leiden University Medical Center (LUMC), the Danstem Institute from the University of Copenhagen and the Murdoch Children’s Research Institute in Melbourne have received 300m euros from the Novo Nordisk foundation. The aim of this new international consortium is to bring stem-cell based therapies…

Professor of Fungal Genetics and Biotechnology Arthur Ram explains how fungi can help us be more sustainable.

Leiden biologists have found a mutation in flour beetles that allows them to speed up their development. The study has been published in Nature Ecology and Evolution.

Many children experience trauma and if they are unable to deal with it properly, it can have a huge personal and societal effect. Building resilience in vulnerable children and young people should therefore have the highest priority. This is the message of Anne-Laura van Harmelen, Professor of Brain,…

New research has revealed that one of Europe’s largest prehistoric mass graves records the deliberate killing of women and children, showing how gender- and age-selective violence was used to disrupt communities and assert power in the Early Iron Age. Leiden archaeologist Jason Laffoon was involved…

In a one-hour interview on Dutch radio programme Sleutelstad, Anne-Laura van Harmelen talks about her research into the role friendships in adolescents' well-being, the resilience paradox and the role of social, hormonal and genetic factors in stress-levels and resilience.

Uncovering ageing processes in the brain and research on the use of the word ‘that’. Thanks to a Rubicon Grant, two Leiden researchers who were recently awarded their PhDs will be able to conduct research at a research institute abroad.

We are congratulating Maaike van der Lee, PhD candidate at LUMC-KFT, for winning the national PhD competition 2021 at the FIGON Dutch Medicine Days. During this national competition, 8 researchers from the major university cities in the Netherlands present their work in the field of innovative medicine…

What are you supposed to do if something goes or has gone wrong? Whether it be a break-in, an accident or an unsafe situation of any other kind, or a data breach or a cyber-attack; please read how to report each type of incident below.

What are you supposed to do if something goes or has gone wrong? Whether it be a break-in, an accident or an unsafe situation of any other kind, or data breach or cyber-attack; please read how to report each type of incident below.

Eleven researchers from Leiden University have been awarded an Open Competition Domain Science ENW XS grant by the Dutch Research Council for their research projects. They are researching how to make software faster and greener, improve cancer detection and reduce anxiety by manipulating the biological…

During the spring of 2021, a group of eight biology students from Leiden set out into the dunes in search of amphibians. Using DNA, they determined the geographic origin of the animals. And guess what? In many cases they discovered exotic populations of animals that do not naturally belong in The Netherlands.…

An international research team is to search for invisible life in the Galápagos Islands. The diversity of bacteria and other microscopic organisms may not be evident to the naked eye, but it is essential to nature. To the islands' giant daisies, for instance: unique endemic plants that are currently…

Since the publication of the article in the interdisciplinary journal Nature, over 200 news outlets have showcased the pioneering research.

Personality is genetic in zebrafish: risk-taking parents have risk-taking children. These are the findings of research by Christian Tudorache and his team published in BMC Neuroscience.

Professor Meta Roestenberg has been awarded the Mercator Sapiens Stimulus 2025 by the Royal Holland Society of Sciences and Humanities (KHMW). The prize of EUR 1 million will allow Roestenberg and her team to further develop an innovative malaria vaccine.

The KNAW has rewarded 11 Leiden scientists for their commitment to science communication, by awarding them 10,000 euros each from the ‘Appreciated!’ fund.

The opportunity to explore a new, exciting research topic. That is how Lennart Schada von Borzyskowski describes his successful application for the NWO XS grant. It comprises 50,000 euros, which the researcher from the Institute of Biology Leiden (IBL) will spend on investigating a more sustainable…

The Rob Schilperoort Memorial will be unveiled at the Leiden Bio Science Park on Saturday 16 September. This gigantic gate stands at the entrance to the park, which is also named after Schilperoort, its founder.

The risk of a brain tumour recurring can be predicted more accurately by counting the number of immune cells in the tumour under a microscope. These are the findings from research conducted by LUMC, Erasmus MC and Heidelberg University.

On 11 November Professor of Gastroenterology and Hepatology, Monique van Leerdam will deliver her inaugural lecture entitled, ‘Aiming for Prevention’. Van Leerdam, who specialises in hereditary tumours, was appointed professor in July 2020. In her inaugural lecture she will discuss the importance of…

How can we view societal challenges from a different perspective? At the EuroScience Open Forum (ESOF), Robert Zwijnenberg, Emeritus Professor of Art and Science Interactions, will call for more collaboration between artists and scientists.

Autism, Alzheimer’s, and bipolar disorder: can the development of these mental health conditions be influenced by the ketogenic diet? Increasingly, research suggests it might. 'For those it helps, it can be life-changing,' says neuroscientist Eline Dekeyster.