Now that university buildings have closed, most staff members have started working from home. How are Faculty of Science colleagues faring in their new offices?

Marlien van Mever delved into the analysis of tiny samples, cerebrospinal fluid from transgenic mouse models for example. She validated methods that can now be used to study brain diseases such as migraine and epilepsy. Van Mever will receive her PhD on 14 June.

This year, two Leiden master students will be awarded a KNMP Student Award. Both Wisse van Os and Jip Linthorst will receive 1,000 euros from the Royal Dutch Pharmacists Association (KNMP) as a reward for their excellent study results, motivation and commitment.

Leiden University is involved in five new NWO Gravitation projects. Two relate to mental disorder and the remaining three to a healthy lifestyle, the combination of human and artificial intelligence, and the special relationship between plants and microbes.

Ilze Bot and Johan Kuiper have published in The Lancet: Study unveils how stress may increase risk of heart disease and stroke. Aso: The National Dutch newspaper 'NRC' has mentioned them in a column

Human cells are protecting their proteins from unfolding and aggregating. That's what biophysicist Alireza Mashaghi and his team discovered after seven years of in-depth research into the folding mechanisms of proteins. With an unprecedented approach, the team was able to study the folding of a single…

A staggering 6.5 billion chicks are killed worldwide every year. These are generally male chicks that are of no economic value. In Ovo has developed technology that can quickly determine the sex of a chick, to ensure that only female chicks are hatched. The first 150,000 chicks have now hatched in this…

When you think of physics, do you think only of complicated formulas? You’re not the only one. Therefore, every year, the Leiden Insitute of Physics organises the LION Image Award to show another side of physics: beautiful images about intriguing science. The winner of the 2022 photo competition captured…

Leiden researchers have developed a groundbreaking model to advance cancer immunotherapy. Using a 3D printer, they create mini-tumors within an environment that closely mimics human tissue. They have also developed a method to monitor real-time interactions of these mini-tumours with immune cells during…

Finding structure in disordered proteins and developing drugs for undruggable diseases: it might sound like mission impossible, but pharmacologist Alireza Mashaghi and his team are right on top of it. Their project was awarded by NWO through the Open Competition Domain Science -XS, a competition that…

Scientists in Leiden are looking for signals in blood samples to predict whether patients will develop serious COVID-19 symptoms or not. Based on that knowledge, they will be able to propose targeted therapies to prevent serious symptoms. They hope to come up with the first results within the week.

Not taking into account the saturation of drug targets can lead to wrong conclusions about the duration of a drug's action. This is what former PhD candidate Wilbert de Witte writes together with the Leiden professors of pharmacology Meindert Danhof, Piet van der Graaf, and Liesbeth de Lange in Nature…

A record number of 83 teams collected a record sum of 10,566.37 euros on 29 September during the Leiden Science Run. The full sum goes to the Foundation for Refugee Students UAF.

Not experiments and lab coats, but computers and artificial intelligence: this year's Nobel Prize in Chemistry went to the inventors of the groundbreaking AI model, AlphaFold. This programme accurately predicts protein structures based on their genetic code—a crucial step in understanding biological…

Marie Curie once said: I have no dress except the one I wear every day. If you are going to be kind enough to give me one, please let it be practical and dark so that I can put it on afterwards to go to the laboratory.

Leiden researchers have carried out successful tests using a new method of packaging a cancer vaccine in nano-particles. The new vaccine has induced a strong immune reaction in mice. The researchers believe that this method can make an important contribution to the treatment of cancer. Their findings…

When you become very good at one thing, that sometimes comes at the expense of something else. Such trade-offs also apply to bacteria. When becoming more resistant to one antibiotic, bacteria can sometimes become more sensitive to another. Linda Aulin, PhD candidate in the pharmacology group of Coen…

Four green research institutes in Leiden are joining forces to integrate evolution and biodiversity research, at local and at the national level. Pivot in this collaboration is Frederic Lens.

Why does a medicine work well for one person, but cause side effects in another? Research by Laura de Jong shows that it’s not just our DNA that matters – other medicines and illnesses can also affect how our bodies respond.

Gianne Derks is the MI’s new scientific director from 1 May. She has worked abroad longer than in the Netherlands and, after more than 27 years in Surrey, she dreams in English. Who is this new director and who or what managed to entice her to make the move to Leiden?

‘Be yourself. Be as gay, queer, trans as you can and show the world you exist.’ These rousing words from Looi van Kessel marked the start of the third Pride Leiden for the university boat, with the theme: ‘450 years of being yourself’.

Nine talented Leiden researchers have been awarded a Vidi subsidy by the Netherlands Organisation for Scientific Research (NWO). Vidis are intended for researchers with several years of research experience who want to set up or expand their own line of research.

What dose of medicine do you give a child? That depends to a large extent on how quickly their kidneys remove the drug from the blood. For ethical reasons it is impossible to measure this directly in little patients. PhD candidate Sinziana Cristea combined different types of modelling and lots of data…

The team of Alireza Mashaghi at the Leiden Academic Centre for Drug Research has found a way to determine and classify the shape of proteins. Their new theory defines the topology of proteins as a simple and precise barcode that allows the identification of all types of folds. ‘This barcode enables…

Tuberculosis stands as one of the most lethal infectious diseases worldwide. A significant challenge in combatting tuberculosis lies in the emergence of antibiotic resistance triggered by genetic alterations, commonly known as mutations. These mutations can diminish the responsiveness to antibiotics,…

To better prepare students for their laboratory education, a team of education experts and students have created a collection of interactive videos. After launching their website labprep.video, the material is now available to everyone in higher education. Project leader Marjo de Graauw: ‘We also created…

Predicting whether someone will fall ill and which treatment will benefit them most: that is the aim of the techniques that Professor of Analytical Biosciences Thomas Hankemeier and his research group are developing at Leiden University. In order to scale up and further develop this technology, he works…

Cancer research generates massive amounts of data, but traditional tools often fail to fully harness their potential. How can we unlock this data to provide better treatments for cancer patients? PhD candidate Marina Gorostiola González explored this by using advanced data analysis techniques to guide…

Eleven talented Leiden researchers with several years of research experience have been awarded a Vidi subsidy to set up or expand their own line of research.

With a call for dialogue and collaboration, vice dean Bart de Smit kicked off the new academic year for the Faculty of Science on Tuesday 3 September. Theoretical physicist Carlo Beenakker outlined the possibilities of quantum as a disruptive technology.

Ten Leiden researchers have been awarded a Veni grant by the Dutch Research Council (NWO). The grant, of up to 280,000 euros, will enable them to elaborate their ideas over a period of three years.

A valuable community of female researchers, providing solicited and unsolicited advice to the Board of the Faculty of Science. Those are the strengths of women’s network RISE. On 11 September the network presented its second biennial report.

How is it that some covid-19 patients are affected much worse than others? Can we predict beforehand which of them will develop critical symptoms Professor Thomas Hankemeier, together with a diverse consortium of universities, academic hospitals and industrial partners, is looking for the answers to…

Liposomes – nano-sized spheres composed of fatty molecules – are very promising for vaccination. Bio-pharmaceutical scientist Naomi Benne discovered that the immune response in animal models can be steered by varying the charge of the liposomes. She obtained her PhD degree on 8 September for this research,…

When children wean off from heavy medication, they often experience withdrawal symptoms. The severity of these symptoms is often difficult to predict. Pharmacologist Bas Goulooze developed a computer model to determine the best weaning strategy for each child. His research has now been published in…

PhD student Esmee Koedoot studied the underlying processes responsible for metastases in a dangerous type of breast cancer. She hopes to find new possibilities to fight the disease. In December 2019 she obtained her doctorate cum laude.

Easily detecting chemical substances that indicate whether or not someone is ill, or measuring how healthy the environment is, and directly linking that result to that person. In a nutshell, this is what researchers within the Dutch National Research Agenda (NWA) want to achieve in the ‘Measuring and…

Leiden University and the Leiden Bio Science Park can make a significant contribution to the earning capacity of the Netherlands. This is the finding of the National Investment Agenda presented today.

Theoretical physicist Luca Giomi receives a 2 million euro ERC Consolidator Grant for research into flowing cells in a strange hexatic phase, which is half fluid, half solid.

During the Faculty of Science New Year's reception, Daniël Rozen was named Discoverer of the year 2015. Nienke van der Marel and Koen van der Maaden both won the prize for the best dissertation and Jeroen van Smeden was named Best Teacher of 2015.

Fighting against cancer, antibiotic resistance and disposable plastics: Ahmed Ali, Fredj Ben Bdira, and Valerio Barbarossa receive a LUF grant for their innovative and socially relevant research. These grants for academic talent are often an important step towards grants by NWO and other grant insti…

Organs and tissues grown in the lab may in the future be able to cure people with organ failures. Micha Drukker, professor of Stem Cells, Developmental Biology and Technology for Innovative Drug Research, is convinced that the use of stem cells will make this possible. He will deliver his inaugural…

The prestigious journal Science Translational Medicine has published a study by researchers from the Institute of Biology Leiden (IBL) on a potent new antibiotic that can overcome resistance. ‘The idea was to tweak the original antibiotic and create a next-generation drug’, says Nathaniel Martin, professor…

An international group of scientists has discovered that certain cells of our immune system – the so-called T cells – communicate with each other and work together as a team. To fight an infection they stimulate each other’s growth, but at the same time, they inhibit each other when there is a surplus…

Erik Danen is looking at how to inhibit tumours that do not respond well to medicine – and he is making some headway. The Professor of Cancer Drug Target Discovery studies the interaction between tumour cells and their surroundings. Inaugural lecture on Friday 10 May.

There are more molecules that could conceivably be candidate drugs than there are stars in the universe. How can we ever efficiently identify those molecules? Professor of AI and Medicinal Chemistry, Gerard van Westen: ‘I’m going to use artificial intelligence as the co-pilot to make an automated search.’…

About one and a half million people worldwide die each year from tuberculosis. For thirty years, therapy with antibiotics has been the same, while it takes far too long and can lead to resistant pathogens. Leiden researchers from four institutes are now joining forces to develop more effective and efficient…

Want to explore a different specialist field? Or maybe study a topic from your programme in more depth? This summer Leiden University is again offering a broad selection of Summer Schools.

The Master of Medicine at Leiden University Medical Center (LUMC) has won the national biennial award for best educational innovation in medical teaching. It was awarded the prize by the Netherlands Association for Medical Education (NVMO) for its MasterMinds Challenge (MMC).

Lecturers Marjo de Graauw and Malte Riemann have both received a Comenius Teaching Fellowship.