117 search results for “metabolic nanoparticles” in the Staff website
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Improving safety assessment of nanoparticles
How safe are the nanoparticles in transparent sunscreen, anti-odour socks and bacteria-resistant plasters? Although microbes are present on all organisms, the tools that estimate the safety of nanomaterials still hardly take them into account. Bregje Brinkmann explored the role of these microbes during…
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The effect of nanoparticles on our planet
‘Solar panels, toothpaste and sport socks. What do these things have in common?’ Martina Vijver, professor of ecotoxicology begins her TEDx-talk. Watch her online lecture if you want to learn more about the effects of nano-particles on our environment and health.
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Publication on the design of multifunctionalized nanoparticles
Despite considerable progress in the design of multifunctionalized nanoparticles (NPs) that selectively target specific cell types, their systemic application often results in unwanted liver accumulation. The exact mechanisms for this general observation are still unclear.
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Hans AertsFaculty of Science
j.m.f.g.aerts@lic.leidenuniv.nl | +31 71 527 4771
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Camille SouamaSocial & Behavioural Sciences
c.p.souama@fsw.leidenuniv.nl | +31 71 527 2727
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Special nanoparticles for cancer therapy! Will you help?
Developing a better treatment for patients with head and neck cancer, that is what Binanox, The 2022 iGEM Leiden team, want to achieve. They hope to raise at least 10,000 euros for this cause. Support their crowdfunding campaign today.
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How drugs work better when encapsulated in nanoparticles
Chemist Tobias Bauer discovered ways to improve drugs by encapsulating them. Packages with iron nanoparticles, for example, can stimulate immune cells. Bauer will receive his PhD on 9 June.
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Alexa SchrickelSocial & Behavioural Sciences
a.schrickel@fsw.leidenuniv.nl | 071 5272727
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Lennart Schada von BorzyskowskiFaculty of Science
l.schada.von.borzyskowski@biology.leidenuniv.nl | 071 5274278
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Nanoparticles: shapeshifters that pass along the food chain and end up in the brain
Nanomaterials can pass much further along the food chain than was previously thought. The particles can change shape and size in each organism, enabling them to pass on to the next one in the chain. Researchers from the Institute of Environmental Sciences discovered this accidentally when using a novel…
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Leiden Scientists: 'Environmental risks of new pesticides with nanoparticles insufficiently examined'
The environmental risks of new pesticides containing nanoparticles are inadequately researched, according to four Leiden scientists in the scientific journal Environmental Science & Technology. They call for an examination of the long-term and environmental effects of pesticides containing nanoparti…
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Eline DekeysterSocial & Behavioural Sciences
e.a.g.dekeyster@fsw.leidenuniv.nl | +31 71 527 2727
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Rik MomFaculty of Science
r.v.mom@lic.leidenuniv.nl | +31 71 527 4221
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Review paper on the potential impact drug-metabolizing enzymes on brain exposure
PhD candidate Mengxu Zhang (Division of Systems Pharmacology and Pharmacy) published a comprehensive and important review on “The potential impact of CYP and UGT drug-metabolizing enzymes on brain target site drug exposure” in Drug Metabolism Reviews.
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Eline Dekeyster in Podcast Metabolic Mind: Can ketogenic therapy help with autism and mental health?
Could ketogenic therapy change the future of autism spectrum disorder (ASD) treatment? Bret Scher sits down with Eline Dekeyster to explore how nutritional ketosis may support individuals with autism and other brain-based conditions.
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What makes us ill?
Genes predict whether you have a propensity for an illness but environmental factors often have the last word: nutrition, air pollution, lifestyle, stress. The exposome as both culprit and chance. Large-scale research is being carried out into this at Leiden. Thomas Hankemeier, Professor of Analytical…
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Malene NeustrupFaculty of Science
m.a.neustrup@lacdr.leidenuniv.nl | +31 71 527 4570
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Aleksandrina SkvortsovaSocial & Behavioural Sciences
a.skvortsova@fsw.leidenuniv.nl | +31 71 527 2727
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Sandra IrmischFaculty of Science
s.irmisch@biology.leidenuniv.nl | +31 71 527 2727
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Miranda van EckFaculty of Science
eck_m@lacdr.leidenuniv.nl | 071 5276238
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Leiden biologists find nanoplastics in developing heart
Nanoplastics can accumulate in developing hearts, according to a study by biologist Meiru Wang from Leiden University. Her research on chicken embryos sheds new light on how these tiny plastic particles pose a threat to our health.
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Robert VerpoorteFaculty of Science
verpoort@chem.leidenuniv.nl | +31 71 527 4528
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Targeting the immune system to inhibit atherosclerosis
A new treatment for atherosclerosis showed promising results in isolated cells but proved to be less effective in initial animal tests. Bachelor student Biopharmaceutical Sciences Willemijn van der Heijden aimed to understand why. She investigated whether the formation of a protein layer around the…
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Laura de JongFaculty of Science
l.m.de.jong@lacdr.leidenuniv.nl | 071 5272727
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New easy-to-use tuberculosis vaccine patch in development
Researchers from Leiden have developed a promising TB vaccine that users can self-administer via a special patch. This could be beneficial for countries with limited health services, says PhD candidate Malene Neustrup.
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Irene GrootFaculty of Science
i.m.n.groot@lic.leidenuniv.nl | +31 71 527 7361
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Phase Separation in Lipid-based Nanoparticles
PhD defence
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Nanoparticles and Microfluidics for Future Tuberculosis Vaccines
PhD defence
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Chao DuFaculty of Science
c.du@biology.leidenuniv.nl | +31 71 527 4947
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Developmental effects of polystyrene nanoparticles in the chicken embryo
PhD defence
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Microglial lipid metabolism: a delicate balance
PhD defence
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Life after the Grand Jamboree: Wrapping-up iGEM
‘A challenging rollercoaster, but also a very bonding and insightful experience,’ that’s how the team of iGEM Leiden 2022 wraps up their participation in the iGEM contest. The contest for synthetic biology climaxed during the Grand Jamboree in Paris. The team ended up in the top 10 of over 360 teams…
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Tomer FishmanFaculty of Science
t.fishman@cml.leidenuniv.nl | +31 71 527 2727
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Shiza AslamFaculty of Science
s.aslam@cml.leidenuniv.nl | +31 71 527 2727
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Liposome-based vaccines for immune modulation: from antigen selection to nanoparticle design
PhD defence
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Elena EgorovaFaculty of Science
e.a.egorova@lic.leidenuniv.nl | +31 71 527 4234
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Modelling the Interactions of Advanced Micro- and Nanoparticles with Novel Entities
PhD defence
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Toxicity, bioaccumulation and trophic transfer of engineered nanoparticles in the aquatic environment
PhD defence
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Kanchana Kallakkudi PandianFaculty of Science
k.kallakkudi.pandian@lacdr.leidenuniv.nl | +31 71 527 2727
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The development of molecular tools for investigating NAD+ metabolism and signalling
PhD defence
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Design and Synthesis of Click Lipids as Tools to Study Immune Cell Metabolism
PhD defence
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A chemical biology approach to explore lipid metabolism in neurological disorders
PhD defence
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Exploring the metabolism and toxicity of amino sugars and 2- deoxyglucose in Streptomyces
PhD defence
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Microstructural and Metabolic Alterations in the Zebrafish Brain Induced by Toll-Like Receptor 2 Deficiency
PhD defence
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The impact of non-genetic factors on drug metabolism: towards better phenotype predictions
PhD defence
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Application of zebrafish and murine models in lipoprotein metabolism and atherosclerosis research
PhD defence
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Quantitative and miniaturised assays for structure-resolved lipidomics in metabolic disease
PhD defence
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Can we make bioplastics with artificial photosynthesis?
Mimicking photosynthesis to produce bioplastics sustainably and efficiently. Researchers from the Institute of Biology Leiden (IBL) and the Leiden Institute of Chemistry (LIC) will assess this new approach. ‘An exciting opportunity to explore a new, appealing research topic in a collaboration between…
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Nutrition and fasting for the brain: why the Keto diet shows promise
Autism, Alzheimer’s, and bipolar disorder: can the development of these mental health conditions be influenced by the ketogenic diet? Increasingly, research suggests it might. 'For those it helps, it can be life-changing,' says neuroscientist Eline Dekeyster.
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Nature Communications paper on therapeutic melanoma inhibition by local micelle-mediated cyclic nucleotide repression
Cancer immunotherapy represents a significant breakthrough in cancer treatment. However, tumors have numerous mechanisms by which they evade destruction by the immune system. It is therefore necessary to decipher and reverse these mechanisms in order to improve immunotherapies.