Classical statistical methods, such as p-values, are difficult for researchers to apply correctly. They for example do not allow drawing conclusions from a study early, or for extending a study with extra research groups that want to make their data available later.

What is the impact of Ramadan on patients with a bipolar disorder? What does it mean to be sensitive to psychiatric patients' religious beliefs? Driss Moussaoui, a Moroccan psychiatrist, talks about this in a video interview with Leiden University's Islam Centre LUCIS.

LUMC Curium and the Dutch National Youth Council (NJR) have been working on integrating young people’s lived experiences of mental health problems in medical research and training. The aim is to broaden doctors' and researchers’ perspectives and improve the care offered.

Piercing through the skull with an ice pick, administering electric shocks without an anaesthetic, or applying leeches to the uterus: these may seem like medieval methods of torture, but they are in fact therapies used in medicine. Willem van der Does writes about all of them in his new book. ‘Physicians…

The person who cried out at Dam Square on Remembrance Day in 2010. For Michiel van der Wolf this marked the rise of a new phenomenon: that of ‘confused people’. Because since that Remembrance Day, the number of reports of ‘confused people’ in the Netherlands has increased rapidly in the statistics.…

Money laundering, fraud, DNA testing: current affairs is key in this master’s programme. 'Forensische Criminologie' provides specialist expertise related to the criminal justice system - from forensic psychiatry to criminalistics.

What are the social and neural mechanisms that contribute to fluctuations in self-esteem in healthy adolescents and adolescents with depression?

Social anxiety runs in families, but the neurobiology underlying this genetic vulnerability is until now largely unknown. The unique Leiden Family Lab study on Social Anxiety Disorder (LFLSAD) aims to broaden our knowledge with respect to this genetic susceptibility.

Disclaimer: Manuscripts related to the Resilience Center are for academic purposes only and are not intended for mass distribution or copying. Please refer to applicable laws for fair use, including copyright holders' restrictions on publications.

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The key question addressed in this family study is whether the psychophysiological and neurocognitive abnormalities often reported in SAD patients are heritable and can thus be found in family members of SAD patients as well. Determination of heritability of these deficiencies is essential for endophenotyping.…

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Elk jaar organiseert het LIBC in samenwerking met de gemeente Leiden een Publieksdag over hersenonderzoek.

Leiden alumni find work in all kinds of interesting places. We gather the stories of our alumni and publish then regularly in our alumni newsletter and in Leidraad magazine. You can find all their stories on this page. They give a good impression of what life is like for Leiden alumni after they have…

Together with researchers from over the world, the ENIGMA-Anxiety Working Group endeavors to unravel the neurobiology of anxiety disorders and related constructs.

Professor of Psychiatry Anne Speckens studied medicine in Leiden and did her psychiatry training there too. She opened the Radboudumc Center for Mindfulness in Nijmegen. What does she do there and how does she look back on her time as a student?

In his book The magic of healing, Willem van der Does talks about 14 pioneers in the history of psychiatry. These pioneers all had one thing in common: they started with a radical idea which led to great enthusiasm.

Mental health issues in the Dutch court: The criminal court as a border guard between the regular Mental Health System and the Criminal Justice system?

PhD defence

This GUTS Special Issue focuses on the dynamic relationship between neurobiological development and social experiences in shaping young people's engagement and contributions to society. It explores how young individuals grow up in an increasingly complex world and how various factors – such as family…

Are the types of school non-attendance which have been evidenced in typically developing youth also found among children and adolescents with an intellectual disability (ID)? If so, which types are most prevalent and thus in greatest need of attention, and what factors (child, family, school/environmental)…

Members of our research team give different types of presentations and lectures.

Electronic versions of our publications can be obtained by sending an e-mail to Esther van den Bos: bosejvanden@fsw.leidenuniv.nl

Neuroimaging research has greatly advanced our insights on how the brain is organized. Now is the time for the next step: Imagine what would be possible when we cannot only map brain-functioning, but use neuroimaging to voluntarily regulate brain-activity!

The Leiden | Islam interview series contains short documentary-style videos including interview flashes with leading scholars in the field of Islam and Muslim societies. With this series, LUCIS aims to show the value of unconventional insights related to Islam and Muslim societies, and to relate them…

The overarching aim of this theme is to increase our understanding of the mechanisms underlying altered cognitive, affective, and social behavior in relation to mental health problems.

How to come to valid risk stratification of alcohol use disorder?

The Editors of PAIR are always interested in suggestions for themed editions. Anyone wishing to propose a theme and/or to assist as a ‘guest editor’ should contact one of the editors of PAIR.

We examine the effect of social learning on emotional competence in children and adolescents with a typical or atypical development.

There are effective treatments for people with autism, says Wouter Staal, professor of Autism Spectrum Disorders, in his inaugural lecture on 4 May. However, it is not yet clear which treatment is most effective for which individual.

Meet the people of the Resilience Center

The brain structure of young people with conduct disorder differs significantly from that of their typically developing peers. This is the conclusion of an international study that analysed more than two thousand MRI scans, recently published in The Lancet Psychiatry. Dr Moji Aghajani, one of the principal…

Somatic symptoms, such as pain, itch, and fatigue have been shown to have a bidirectional relationship with mental symptoms. Although acute somatic symptoms serve some adaptive properties, chronic symptoms can instead lead to interference in daily activities and lower quality of life.

While many healthcare professionals indicate that they frequently use placebo effects and their mechanisms, there is little formal training on how to deal with placebo and nocebo effects in clinical practice. This project aims to address this gap between scientific knowledge on placebo and nocebo effects…

Adoptees in the Netherlands generally do not use more medication than their non-adopted peers.

Positive expectations can influence sensations of itch and evoke placebo effects, whereas negative expectations can trigger nocebo effects in itch. There is evidence that placebo effects can occur even when people know that they are taking a placebo. Little is known about how these so-called open-label…

In the Dutch healthcare system, only MHC psychologists (GZ-psychologen) are licensed to practice psychology unsupervised.

Psychologist Ilse van de Groep found that people react more aggressively when receiving negative feedback. However, if people already exhibit persistent antisocial behavior they do not respond even more aggressively to negative feedback.This research earned her the Koningsheide Prize 2022 for the scientific…

Autism, Alzheimer’s, and bipolar disorder: can the development of these mental health conditions be influenced by the ketogenic diet? Increasingly, research suggests it might. 'For those it helps, it can be life-changing,' says neuroscientist Eline Dekeyster.

For Humans of Psychology, students and staff will be put into the spotlight. At our institute prizes are won, exiting research is conducted, knowledge is harnessed, public meeting are organised and open science is highlighted. Take a look behind the scenes.