Medicines can work even if they have no active ingredient. The first international scientific conference on placebos will take place in Leiden from 2 to 4 April. Placebo researcher Andrea Evers, who is also chairing the conference, answers some pressing questions.

It is becoming increasingly clear that the placebo effect has a great influence on medical treatment. An international, interdisciplinary team of researchers led by Professor of Health Psychology Andrea Evers from Leiden University has now written a first set of guidelines on how to apply the placebo…

PhD candidate Dennis Wander searches for the best of both worlds. That is to say: a cancer drug that is effective and also has minimal side effects. To this end, he makes new molecules inspired by two existing medicines. And not without result: ‘We have created a new variant that is very promising.’…

Health psychologist Aleksandrina Skvortsova has made clever use of the Pavlov effect to link the ‘cuddle’ hormone oxytocin with the placebo effect. This effect can alter the level of oxytocin in the body, making it possible for people to reduce the amount of medicine they need while still feeling good.…

This thesis has shed light on some of the ways in which the local electrolyte composition can differ from the bulk and how these changes in the local reaction environment can determine the activity and/or selectivity of two important electrocatalytic reactions, namely, electrochemical CO2 reduction…

Recent studies have shown that Dutch secondary school pupils experience a great deal of stress from school work, and between 2001 and 2007 the number of adolescents experiencing school stress even doubled. The study carried out by Simone Vogelaar focuses on stress factors and the effectiveness of the…

Research conducted at Leiden has established that guts-on-chips respond in the same way to aspirin as real human organs do. This is a sign that these model organs are good predictors of the effect of medical drugs on the human body. Publication in Nature Communications on 15 August.

Spatial analysis on the basis of material culture has always been one of the major topics in archaeological research. Designating Place analyses the urban space of Roman Ostia and Pompeii in different ways, namely via geophysical analysis, spatial analysis, iconographic analysis and epigraphic analy…

How can theatricality act as a mediating process between public space and public as ‘audience’? Does the presence of an observer change the nature of the observed and if so, how?

The tuk-tuk of the European City Of Science Leiden 2022 sent science on its way to the neighbourhood. On the Vijf Meiplein in Leiden, Andrea Evers' placebo team pitched its tent to everyone who wanted to know more about the effect of words and expectations. Experience the day of the placebo effect in…

According to the LUMC, patients experience 30% fewer serious side effects when medication doses are tailored to their DNA.

On 20 October 2021 Michael Ramsden defended the thesis 'The Role of the United Nations General Assembly in Advancing Accountability for Atrocity Crimes: Legal Powers and Effects'. The doctoral research was supervised by Prof. N.M. Blokker.

This article examines leadership encouragement and psychological safety as antecedents of prosocial rule-breaking (PSRB) behaviour.

This thesis focusses on the temperature structure in protoplanetary disks. The relation between structures seen in the dust and gas-phase molecules is investigated.

Tuberculosis (TB) is a major global health problem caused by the bacterium Mycobacterium tuberculosis (Mtb). In 2015, there were estimated to be 10.4 million new cases and 1.8 million deaths ascribed to TB, making it one of the top 10 causes of death worldwide. Unfortunately, the only current registered…

In this thesis I examine how soil biotic and abiotic characteristics change and interact throughout the course of afforestation and how they subsequently impact tree performance.

More collaboration, combining data and asking the right questions. These are a few of the recommendations that policymakers and researchers formulated at the conference 'Data gedreven Beleidsontwikkeling' on 28 November 2017.

The trial of Dutch rapper Ali B is receiving massive media attention. Party due to himself, the trial can be followed by the public. How will this affect the upcoming verdict? Dutch newspaper ‘De Volkskrant’ spoke to legal scholars and experts including Jan de Keijser.

First author Scott Waitukaitis and principal investigator Martin van Hecke have made the cover of Nature Physics with their publication on a newly discovered effect. The Elastic Leidenfrost effect explains why hydrogel balls jump around on a hot plate making high pitched sounds.

In their article; The Effects of Legal Measures to Empower Supervisory Directors: Evidence from a Financial Distress Perspective, Santen and De Bos discuss the relationship between the corporate governance structure of a company and its financial performance. Until now studies predominantly hypothesize…

How can you increase the effectiveness of inspectors using responsible artificial intelligence (AI)? This is the question the Innovation Center for Artificial Intelligence (ICAI) Lab AI4Oversight is tackling. By developing algorithms and methods, they try to provide optimal support for, for example,…

On 22 January, Annemarie Madani-Abbing will defend her dissertation 'Art therapy and anxiety' regarding her research into the effectiveness of anthroposophic art therapy in treating anxiety in women. We asked her about her research and what it was like to combine a job outside academia with studying…

A coronavirus booster shot provides a better immune response against COVID-19 than a single vaccine dose. mRNA boosters are the most effective upon receiving Janssen. These are the results of a collaborative study between several organisations, including the Leiden University Medical Center (LUMC).…

Promotor: A. Achúcarro, Co-promotor: A. Boyarsky

Researchers Indu Khatri, Frank Staal and Jacques van Dongen from Leiden University Medical Center (LUMC) have published a perspective article in Frontiers in Immunology about coronavirus and its characteristic ‘spike protein.’ They predict which antibodies would provide the best protection against the…

The LeidenGlobal Course ‘Discipline and Place' for ResMA and PhD students highlights the interaction of the disciplinary theory and the method with realities, representations, and issues of place, with lectures by fourteen LeidenGlobal experts. Registration is open until September 6th.

The organizing committee has decided that the conference will take place fully online. We hope to provide more information about the particular online circumstances of the conference in January and how this decision may affect the format of the conference, as well as the registration fees.

Rare-earth materials are prime candidates for storing quantum information, because the undesirable interaction with their environment is extremely weak. Consequently however, this lack of interaction implies a very small response to light, making it hard to read and write data. Leiden physicists have…

Primary Objective: The primary aim of the proposed RCT is to evaluate whether LF-TLP in blended form as an indicated prevention for anxiety complaints is more (cost-) effective than TAU according to the NHG guideline Anxiety. We hypothesize that in comparison to TAU, LF-TLP will result in a significantly…

Nausea, neurologic pain and hair loss: some of the severe side effects of chemotherapy. Not necessary, biochemist Liyan Zhang showed. Together with Leiden biologists and others, she achieved great results with a drug that is only active in combination with light. Zhang will defend her PhD on 4 July.

The latest research from the Leiden outdoor laboratory ‘Living Lab’ shows that the insecticide thiacloprid strongly influences even the most common and robust dragonfly species in the Netherlands. The study was published in the Journal of Applied Ecology.

A consortium led by Eefje Cuppen, Professor Governance of Sustainability at the Institute of Public Administration, has been granted NWO funding for a research project looking into the social, societal, and technical aspects of the energy transition.

Human measures to protect lions have an impact on the genetic health of populations. Leiden and Kenyan scientists discovered this by analysing the DNA of 171 Kenyan lions. ‘By fencing reserves, for example, the chance of inbreeding increases.’ With the knowledge and tools from the research, management…

The last time they visited Campus The Hague was back in March, the pupils from The Hague department of ICM Weekend School. On Sunday 13 September, they were finally able to continue their lessons, corona proof. A report of the kick-off for the new school year for third-year pupils and their parents,…

One of the objections to the Comprehensive Economic and Trade Agreement between Canada and Europe (Ceta) is that countries would be surrendering national sovereignty to multinationals which will obstruct effective climate policy. But compared to other trade agreements, CETA is an improvement.

A discovery made in Leiden helps not only to make natural gas from CO2 but also to store renewable energy. Research by Professor Marc Koper and PhD student Jing Shen shows how this process can be implemented in a cost-effective and controllable way. Nature Communications, 2 september 2015.

Following the Mangold and Kücükdeveci case law of the CJEU, the horizontal direct effect of EU general principles and of provisions of the Charter of Fundamental Rights became a hotly debated issue.

Advanced sensing techniques require graphene with high quality and well-controlled surface chemistry.

Extremely painful chronic cluster headaches – sometimes referred to as ‘suicide headaches’ – can be prevented by stimulating the occipital nerve in the back of the head, according to research conducted by Professor Emeritus of Neurology Michel Ferrari from Leiden University Medical Center (LUMC). The…

A child who receives fewer nutrients in the womb than their identical twin brother or sister is more likely to have developmental problems later in life. This is what researchers from the Leiden University Medical Center (LUMC) write in The Lancet Child & Adolescent Health. This study shows that unfavourable…

Discovering effective new drugs is a long, expensive and uncertain process. Laura Heitman wants to improve this by finding out more about how drugs bind to proteins that play a role in disease. She calls it ‘drug discovery 3.0’. Inaugural lecture on 9 December.

The aim of this study is to identify the side effects during treatment with methylphenidate and to investigate how children experience the use of the medication (such as Ritalin, Concerta and Medikinet).

People who have negative expectations about a treatment actually experience more pain. Merve Karacaoglu discovered in her PhD research that anxious and pessimistic individuals are particularly susceptible to this nocebo effect. However, this sensitivity comes with a silver lining.

Patients on patient forums share all sorts of things about their illness: from side effects and advice to messages of support. PhD candidate Anne Dirkson uses artificial intelligence (AI) to retrieve this information. ‘Ninety per cent of the side effects weren’t officially registered.’

Researchers of the Leiden University Medical Centre (LUMC) and the Leiden Institute of Chemistry have made an important discovery about the commonly used anti-cancer drug doxorubicin. They have found a way to reduce its side effects without sacrificing the effectiveness of the medication. This is encouraging…

Since the beginning of September, it is a fact: our faculty has a new strategic plan. The plan outlines what we will collectively commit to in the coming years. Is that important? For sure, say our directors Suzanne van der Pluijm (Operations) and Bart de Smit (Education). ‘The purpose of a strategic…

‘Discipline and Place’ is a lecture series offered by LeidenGlobal to PhD and Research MA students in the Fall of 2020. It gives students an opportunity to reflect on the broader field of the Social Sciences and the Humanities – including Archaeology and Law – and to position their own research accordingly.…

The Life in Custody (LIC) Study comprises a large-scale research project into prison climate and the quality of prison life in Dutch prisons.